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Identifier: 15679329

GI number: 15679329

Start: 1196831

End: 1197421

Strand: Direct

Name: Not Available

Synonym: MTH1329

Alternate gene names: 15679329

Gene position: 1196831-1197421 (Clockwise)

Preceding gene: 15679328

Following gene: 15679330

Centisome position: 68.34

GC content: 51.61

Gene sequence:

>591_bases
ATGAAAATGATAAGATACGGTGAAATTAAAATAAAGACCTGCGAAAACGTCTATGAACCAGCAGAGGACACCTTCCTCCT
TGCAGATAACCTGGATGTCAGGGAGGGTGATCGTGTCCTTGAAATAGGTACAGGAACAGGACTTGTTGCCATAAGAGCAT
CAGAGAAGGGAGATGTGACTGCAACCGATGTGAATCCCGCCGCAGTTAAGTGCACGCAGGAGAATGCCATTATCAATGGA
GTTGAACTCAGGGTCCTGCAGGGGGACCTCTTTGACCCGGTTGAGGGCGAAAAATTTGACGTCATCCTCTTCAACACACC
CTACCTTCCAGCCACCGGGGATGATGCCACAGGGGATGTCCTGGACCTCGCCTGGAATGGGGGCCCCGACGGCAGGATGG
TTATAGACAGGTTCCTTGATGAGGTCCCGGCACACCTGAAACCTGGGGGGAGGGTCCAGCTGGTGCAGTCCTCCCTCTCC
GATACAGAGAAGACCCTCCAGAAACTGGCAGATATGGGCTTTGATGCGTCGGTTACTGCAAGTGAGAGGTACTTCTTTGA
GGAGATAGTCCTGATAACAGCCATGATTTAA

Upstream 100 bases:

>100_bases
GACGTTACAGCCCCTCCCTCATCCTTGCCCACAGGATCGCAAGGGCCCTGGGAAGGGAGCATATCGAGGATATCTTCATC
CTTGATGAGGACGGTGCAAA

Downstream 100 bases:

>100_bases
TAAAAAAATTTTATAACCACCACTGAGCTGGTGTGTCATGTTTTTCCAGTTTTTTTAATCGCCCATCGATTTATGGCGAG
TCCCCCGTTTATATACCTAC

Product: methyltransferase related protein

Products: NA

Alternate protein names: M.MjaHemkP [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKMIRYGEIKIKTCENVYEPAEDTFLLADNLDVREGDRVLEIGTGTGLVAIRASEKGDVTATDVNPAAVKCTQENAIING
VELRVLQGDLFDPVEGEKFDVILFNTPYLPATGDDATGDVLDLAWNGGPDGRMVIDRFLDEVPAHLKPGGRVQLVQSSLS
DTEKTLQKLADMGFDASVTASERYFFEEIVLITAMI

Sequences:

>Translated_196_residues
MKMIRYGEIKIKTCENVYEPAEDTFLLADNLDVREGDRVLEIGTGTGLVAIRASEKGDVTATDVNPAAVKCTQENAIING
VELRVLQGDLFDPVEGEKFDVILFNTPYLPATGDDATGDVLDLAWNGGPDGRMVIDRFLDEVPAHLKPGGRVQLVQSSLS
DTEKTLQKLADMGFDASVTASERYFFEEIVLITAMI
>Mature_196_residues
MKMIRYGEIKIKTCENVYEPAEDTFLLADNLDVREGDRVLEIGTGTGLVAIRASEKGDVTATDVNPAAVKCTQENAIING
VELRVLQGDLFDPVEGEKFDVILFNTPYLPATGDDATGDVLDLAWNGGPDGRMVIDRFLDEVPAHLKPGGRVQLVQSSLS
DTEKTLQKLADMGFDASVTASERYFFEEIVLITAMI

Specific function: Putative protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Homo sapiens, GI87159829, Length=190, Percent_Identity=34.2105263157895, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI87159831, Length=187, Percent_Identity=30.4812834224599, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193204212, Length=192, Percent_Identity=36.4583333333333, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320344, Length=184, Percent_Identity=32.0652173913043, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI78706836, Length=185, Percent_Identity=32.4324324324324, Blast_Score=87, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004557
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 21399; Mature: 21399

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMIRYGEIKIKTCENVYEPAEDTFLLADNLDVREGDRVLEIGTGTGLVAIRASEKGDVT
CCCEEECCEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCEE
ATDVNPAAVKCTQENAIINGVELRVLQGDLFDPVEGEKFDVILFNTPYLPATGDDATGDV
EECCCCCEEEEECCCCEECCEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCE
LDLAWNGGPDGRMVIDRFLDEVPAHLKPGGRVQLVQSSLSDTEKTLQKLADMGFDASVTA
EEEEECCCCCCHHHHHHHHHHCCHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEC
SERYFFEEIVLITAMI
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKMIRYGEIKIKTCENVYEPAEDTFLLADNLDVREGDRVLEIGTGTGLVAIRASEKGDVT
CCCEEECCEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCEE
ATDVNPAAVKCTQENAIINGVELRVLQGDLFDPVEGEKFDVILFNTPYLPATGDDATGDV
EECCCCCEEEEECCCCEECCEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCE
LDLAWNGGPDGRMVIDRFLDEVPAHLKPGGRVQLVQSSLSDTEKTLQKLADMGFDASVTA
EEEEECCCCCCHHHHHHHHHHCCHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEEC
SERYFFEEIVLITAMI
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]