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Identifier: 15679052

GI number: 15679052

Start: 944752

End: 945612

Strand: Direct

Name: Not Available

Synonym: MTH1034

Alternate gene names: 15679052

Gene position: 944752-945612 (Clockwise)

Preceding gene: 15679051

Following gene: 15679053

Centisome position: 53.94

GC content: 50.17

Gene sequence:

>861_bases
ATGGAAAAAAGAGAAAACCCTTACCTCAGGTATCTCAGAAGGGAGAGGCTTCCACACATATTCTGTGCAGGATGTGGTAA
TGGAATAGTCCTCAACAGTTTCTTCAAGGGCATGGAGATGGCCGGCATTGACTTTGATAACATTGCAATGGTTTCAGGTA
TAGGCTGCTCCTCAAGGATTCCAGGTTACGTTAACTGTGACTCACTCCACACAACCCATGGAAGGCCCATATCCTTTGCA
ACCGGTCTCAAGCTAGGGAACCCCTCACTTGACGTGGTTGTATTCACAGGGGATGGTGACGCCGCAGCCATAGGAGGTAA
TCACCTCATCCATGGTGCCAGGCGGAACATCGACATGACGGTGATCTGTATCAACAACAGCATATATGGGATGACAGGCG
GTCAGATAAGCCCAACTTTCCCGGAGGGTAGCTATGGGAGTACCGCACCATATGGAGCTCTTGAGGATCCATTTGACCTT
GCAGAGCTTGTAACCGCTGCCGGGGCAAGTTATGTGGCCCGATGGACCACCGCACATCCCCTCCAGCTTGCAAACTCCAT
AAAGAAGGGGCTGAAGAACAGGGGTTTCTCATTCATAGAGGCCATATCCCAGTGCCCCACCTACTTCGGGAGGAAAAACA
GGATGCGCTCCCCGGTGGAGATGATGAGGTTCATGAAGGAGAACAGCCTTAACAGGAGGAAGGCCCTTAAGATGGAACCA
GATGAAGTTGAGGGTAAAATCATAGTTGGAGAATTTGCAAACAGGCCACAGCCTGAACTCTGCGAAAAGATCTGCAGTAT
GGTTGATGAGAAGTCAGGCAGGGCCCTTGATATGATCAGATCAGCTTACCGGGATGATTGA

Upstream 100 bases:

>100_bases
ATGGCTGAGGTTGAACTCCTCCCGAAGATTGGTGGGGAGATCCACAGGCCAGAGGAGATCCTCAACATGATCTTGAAGAT
GAACAGATAGGAGTGTTTAG

Downstream 100 bases:

>100_bases
AGTGAGAAAGGAAATCAGAATAGCTGGATTCGGTGGACAGGGAGTTATACTTGCAGGCATAGTCCTTGGTAAGGCTGCAA
GTCTCTATGATGGTCTATAC

Product: 2-oxoglutarate ferredoxin oxidoreductase subunit beta

Products: NA

Alternate protein names: 2-ketoglutarate oxidoreductase beta chain; KOR; 2-oxoglutarate-ferredoxin oxidoreductase subunit beta

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MEKRENPYLRYLRRERLPHIFCAGCGNGIVLNSFFKGMEMAGIDFDNIAMVSGIGCSSRIPGYVNCDSLHTTHGRPISFA
TGLKLGNPSLDVVVFTGDGDAAAIGGNHLIHGARRNIDMTVICINNSIYGMTGGQISPTFPEGSYGSTAPYGALEDPFDL
AELVTAAGASYVARWTTAHPLQLANSIKKGLKNRGFSFIEAISQCPTYFGRKNRMRSPVEMMRFMKENSLNRRKALKMEP
DEVEGKIIVGEFANRPQPELCEKICSMVDEKSGRALDMIRSAYRDD

Sequences:

>Translated_286_residues
MEKRENPYLRYLRRERLPHIFCAGCGNGIVLNSFFKGMEMAGIDFDNIAMVSGIGCSSRIPGYVNCDSLHTTHGRPISFA
TGLKLGNPSLDVVVFTGDGDAAAIGGNHLIHGARRNIDMTVICINNSIYGMTGGQISPTFPEGSYGSTAPYGALEDPFDL
AELVTAAGASYVARWTTAHPLQLANSIKKGLKNRGFSFIEAISQCPTYFGRKNRMRSPVEMMRFMKENSLNRRKALKMEP
DEVEGKIIVGEFANRPQPELCEKICSMVDEKSGRALDMIRSAYRDD
>Mature_286_residues
MEKRENPYLRYLRRERLPHIFCAGCGNGIVLNSFFKGMEMAGIDFDNIAMVSGIGCSSRIPGYVNCDSLHTTHGRPISFA
TGLKLGNPSLDVVVFTGDGDAAAIGGNHLIHGARRNIDMTVICINNSIYGMTGGQISPTFPEGSYGSTAPYGALEDPFDL
AELVTAAGASYVARWTTAHPLQLANSIKKGLKNRGFSFIEAISQCPTYFGRKNRMRSPVEMMRFMKENSLNRRKALKMEP
DEVEGKIIVGEFANRPQPELCEKICSMVDEKSGRALDMIRSAYRDD

Specific function: Unknown

COG id: COG1013

COG function: function code C; Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KORB_METTH (O27113)

Other databases:

- EMBL:   AE000666
- PIR:   A69005
- RefSeq:   NP_276169.1
- ProteinModelPortal:   O27113
- STRING:   O27113
- GeneID:   1471442
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1034
- NMPDR:   fig|187420.1.peg.1024
- eggNOG:   arNOG04645
- HOGENOM:   HBG308756
- OMA:   THGRAIP
- ProtClustDB:   PRK05778
- BioCyc:   MTHE187420:MTH1034-MONOMER
- BRENDA:   1.2.7.3
- InterPro:   IPR011766

Pfam domain/function: PF02775 TPP_enzyme_C

EC number: =1.2.7.3

Molecular weight: Translated: 31476; Mature: 31476

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRENPYLRYLRRERLPHIFCAGCGNGIVLNSFFKGMEMAGIDFDNIAMVSGIGCSSRI
CCCCCCHHHHHHHHHCCCEEEEECCCCCEEHHHHHCCHHCCCCCCCCCCEEECCCCCCCC
PGYVNCDSLHTTHGRPISFATGLKLGNPSLDVVVFTGDGDAAAIGGNHLIHGARRNIDMT
CCEEECCCCCCCCCCCEEHCCCCEECCCCEEEEEEECCCCEEEECCCCEEECCCCCCCEE
VICINNSIYGMTGGQISPTFPEGSYGSTAPYGALEDPFDLAELVTAAGASYVARWTTAHP
EEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCH
LQLANSIKKGLKNRGFSFIEAISQCPTYFGRKNRMRSPVEMMRFMKENSLNRRKALKMEP
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHCCCCCC
DEVEGKIIVGEFANRPQPELCEKICSMVDEKSGRALDMIRSAYRDD
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MEKRENPYLRYLRRERLPHIFCAGCGNGIVLNSFFKGMEMAGIDFDNIAMVSGIGCSSRI
CCCCCCHHHHHHHHHCCCEEEEECCCCCEEHHHHHCCHHCCCCCCCCCCEEECCCCCCCC
PGYVNCDSLHTTHGRPISFATGLKLGNPSLDVVVFTGDGDAAAIGGNHLIHGARRNIDMT
CCEEECCCCCCCCCCCEEHCCCCEECCCCEEEEEEECCCCEEEECCCCEEECCCCCCCEE
VICINNSIYGMTGGQISPTFPEGSYGSTAPYGALEDPFDLAELVTAAGASYVARWTTAHP
EEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCH
LQLANSIKKGLKNRGFSFIEAISQCPTYFGRKNRMRSPVEMMRFMKENSLNRRKALKMEP
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHCCCCCC
DEVEGKIIVGEFANRPQPELCEKICSMVDEKSGRALDMIRSAYRDD
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463