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Identifier: 15679023

GI number: 15679023

Start: 918054

End: 918875

Strand: Direct

Name: Not Available

Synonym: MTH1005

Alternate gene names: 15679023

Gene position: 918054-918875 (Clockwise)

Preceding gene: 15679022

Following gene: 15679024

Centisome position: 52.42

GC content: 52.8

Gene sequence:

>822_bases
TTGATTTTAATGGACCCCGAAGAAACCGGGAAGGCCCCCGAGATCAGGGCCCTTAAATCCAGGGCAGTGAACAGGGTTGA
TTCCGACCTCGGCCGGATGGAGGCTGTTAAAAGATTGAAGGGTGTTGAGGACCGGCGGGTCGGTAGCGAGGTCTTTGATG
AGCTGACCCTCAAAACCCTCTACAAGCTGGCGAATTCAGGTTACCTTGCTGTTCTCAATGGTGCTGTGAGTACCGGGAAG
GAGGCCAATGTCTTCAAGGGCATCACAGACACCGACGACTTCGTTGCAGTCAAGATCTACCGGGTGGCCACATCCGACTT
CAAGAAGATGCAGTACTACATCCAGGGGGACCCCAGATTCAAGGTCAGGACAACAAACAGGCGCCAGCTGGTCCAGGCCT
GGGTTAACAAGGAATTCCGGAACCTTAAGAGGGCACTTGAGGCAGGGGTCCGTGTACCGGAACCGGTCACTGCAAGGGAC
AATGTGCTCATAATGGAATTCATTGGGAAGGATGGTGTTCCGGCGCCCACCATGCGGGACGCCCCACCAGAGGACCCTGA
GGAAGCCCTTGAGACAATAATTGAATACATGCACCGCCTCTATAAGGGAGCCCGGCTTGTCCATGGGGATCTATCATTCT
TCAACATACTCAACCATTGCGGTGAACCCGTGATAATAGATGTATCCCAGGCAATGGTGCTTGACCATCCCCTTGCCGGC
GAACTCCTTGAAAGGGACATAGAGAACATAATACGTGACTTCAGAAGGATAGGAGTTTCTGTAAGTGCAGATTATATCCG
GGAGAGGATAACCGGAAAGTGA

Upstream 100 bases:

>100_bases
CCTGGGAGTTCCAGAGCGAAGAGAAGGCTGATATCGTCTGGAGATACACACGTACAGAGTCAAACTGGCTCGAAAGGAAG
GGTTACCTTAAACTGTAAAG

Downstream 100 bases:

>100_bases
ACATGAAGAACCGGGAAAACATATATACTGTAGAAAAAAACCAGTATGATGTTAGGGGTCTCTACAGGGAATAAACAGCA
GATCCATAGGCCAGGAAGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MILMDPEETGKAPEIRALKSRAVNRVDSDLGRMEAVKRLKGVEDRRVGSEVFDELTLKTLYKLANSGYLAVLNGAVSTGK
EANVFKGITDTDDFVAVKIYRVATSDFKKMQYYIQGDPRFKVRTTNRRQLVQAWVNKEFRNLKRALEAGVRVPEPVTARD
NVLIMEFIGKDGVPAPTMRDAPPEDPEEALETIIEYMHRLYKGARLVHGDLSFFNILNHCGEPVIIDVSQAMVLDHPLAG
ELLERDIENIIRDFRRIGVSVSADYIRERITGK

Sequences:

>Translated_273_residues
MILMDPEETGKAPEIRALKSRAVNRVDSDLGRMEAVKRLKGVEDRRVGSEVFDELTLKTLYKLANSGYLAVLNGAVSTGK
EANVFKGITDTDDFVAVKIYRVATSDFKKMQYYIQGDPRFKVRTTNRRQLVQAWVNKEFRNLKRALEAGVRVPEPVTARD
NVLIMEFIGKDGVPAPTMRDAPPEDPEEALETIIEYMHRLYKGARLVHGDLSFFNILNHCGEPVIIDVSQAMVLDHPLAG
ELLERDIENIIRDFRRIGVSVSADYIRERITGK
>Mature_273_residues
MILMDPEETGKAPEIRALKSRAVNRVDSDLGRMEAVKRLKGVEDRRVGSEVFDELTLKTLYKLANSGYLAVLNGAVSTGK
EANVFKGITDTDDFVAVKIYRVATSDFKKMQYYIQGDPRFKVRTTNRRQLVQAWVNKEFRNLKRALEAGVRVPEPVTARD
NVLIMEFIGKDGVPAPTMRDAPPEDPEEALETIIEYMHRLYKGARLVHGDLSFFNILNHCGEPVIIDVSQAMVLDHPLAG
ELLERDIENIIRDFRRIGVSVSADYIRERITGK

Specific function: Unknown

COG id: COG1718

COG function: function code TD; Serine/threonine protein kinase involved in cell cycle control

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI23510356, Length=244, Percent_Identity=40.1639344262295, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI22325377, Length=237, Percent_Identity=35.0210970464135, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI23510358, Length=134, Percent_Identity=45.5223880597015, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI229331971, Length=250, Percent_Identity=25.2, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI229331967, Length=250, Percent_Identity=25.2, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532073, Length=229, Percent_Identity=42.3580786026201, Blast_Score=175, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17556977, Length=246, Percent_Identity=36.1788617886179, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71989043, Length=147, Percent_Identity=40.8163265306122, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6324693, Length=272, Percent_Identity=32.3529411764706, Blast_Score=147, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324122, Length=260, Percent_Identity=23.8461538461538, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24662811, Length=229, Percent_Identity=39.7379912663755, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21356879, Length=229, Percent_Identity=39.7379912663755, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI19920700, Length=240, Percent_Identity=36.6666666666667, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24649986, Length=258, Percent_Identity=23.6434108527132, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR018934
- InterPro:   IPR000687
- InterPro:   IPR018935
- InterPro:   IPR008266 [H]

Pfam domain/function: PF01163 RIO1 [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 30892; Mature: 30892

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMDPEETGKAPEIRALKSRAVNRVDSDLGRMEAVKRLKGVEDRRVGSEVFDELTLKTL
CEEECCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
YKLANSGYLAVLNGAVSTGKEANVFKGITDTDDFVAVKIYRVATSDFKKMQYYIQGDPRF
HHHHCCCEEEEEECCCCCCCCCHHHCCCCCCCCEEEEEEEHHHHHHHHHHEEEECCCCEE
KVRTTNRRQLVQAWVNKEFRNLKRALEAGVRVPEPVTARDNVLIMEFIGKDGVPAPTMRD
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
APPEDPEEALETIIEYMHRLYKGARLVHGDLSFFNILNHCGEPVIIDVSQAMVLDHPLAG
CCCCCHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCEEEECHHHHHHCCCHHH
ELLERDIENIIRDFRRIGVSVSADYIRERITGK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MILMDPEETGKAPEIRALKSRAVNRVDSDLGRMEAVKRLKGVEDRRVGSEVFDELTLKTL
CEEECCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
YKLANSGYLAVLNGAVSTGKEANVFKGITDTDDFVAVKIYRVATSDFKKMQYYIQGDPRF
HHHHCCCEEEEEECCCCCCCCCHHHCCCCCCCCEEEEEEEHHHHHHHHHHEEEECCCCEE
KVRTTNRRQLVQAWVNKEFRNLKRALEAGVRVPEPVTARDNVLIMEFIGKDGVPAPTMRD
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
APPEDPEEALETIIEYMHRLYKGARLVHGDLSFFNILNHCGEPVIIDVSQAMVLDHPLAG
CCCCCHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCEEEECHHHHHHCCCHHH
ELLERDIENIIRDFRRIGVSVSADYIRERITGK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]