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Identifier: 15678843

GI number: 15678843

Start: 746136

End: 746342

Strand: Direct

Name: Not Available

Synonym: MTH821

Alternate gene names: 15678843

Gene position: 746136-746342 (Clockwise)

Preceding gene: 15678841

Following gene: 15678844

Centisome position: 42.6

GC content: 42.03

Gene sequence:

>207_bases
ATGGCTGAATTACCAATTGCACCAGTAGGTAGAATAATAAAAAATGCCGGTGCCCAGAGAATAAGTGATGATGCAAAAGA
GGCTTTAGCAAAGGCCCTTGAAGAAATGGGTGAAGAAATCTCACGCAAAGCCGTTGAACTTGCAAAACACGCCGGCAGAA
AAACTGTTAAAGCCACAGACATAGAAATGGCCGCTAAACAGTTATAA

Upstream 100 bases:

>100_bases
CACACCCATTCAACCCCATATGGTCCATGTGGTCCATTAATCACCCGTAACCAATAAATTTAAATATTAGAGCGTACCAG
CTTAATTTGGAGGTGAAATT

Downstream 100 bases:

>100_bases
TTAGATCTTATTACTACTATTTATTTATTTTTAGGGACACTGCAAATTTTAATCTAATTTTAGGGCCTCTACTTCCTGAT
TGTATCTCCATTCCCCTTCT

Product: histone HMtA1

Products: NA

Alternate protein names: Archaeal histone A1

Number of amino acids: Translated: 68; Mature: 67

Protein sequence:

>68_residues
MAELPIAPVGRIIKNAGAQRISDDAKEALAKALEEMGEEISRKAVELAKHAGRKTVKATDIEMAAKQL

Sequences:

>Translated_68_residues
MAELPIAPVGRIIKNAGAQRISDDAKEALAKALEEMGEEISRKAVELAKHAGRKTVKATDIEMAAKQL
>Mature_67_residues
AELPIAPVGRIIKNAGAQRISDDAKEALAKALEEMGEEISRKAVELAKHAGRKTVKATDIEMAAKQL

Specific function: Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils

COG id: COG2036

COG function: function code B; Histones H3 and H4

Gene ontology:

Cell location: Cytoplasm (Potential). Chromosome (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal histone HMF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HMT1_METTH (P50483)

Other databases:

- EMBL:   M90086
- EMBL:   AE000666
- PIR:   G69209
- RefSeq:   NP_275960.1
- ProteinModelPortal:   P50483
- SMR:   P50483
- STRING:   P50483
- GeneID:   1471229
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH821
- NMPDR:   fig|187420.1.peg.815
- eggNOG:   arNOG12578
- HOGENOM:   HBG392052
- OMA:   IRTAGAH
- ProtClustDB:   CLSK798004
- BioCyc:   MTHE187420:MTH821-MONOMER
- GO:   GO:0005694
- GO:   GO:0005737
- InterPro:   IPR003958
- InterPro:   IPR009072
- Gene3D:   G3DSA:1.10.20.10

Pfam domain/function: PF00808 CBFD_NFYB_HMF; SSF47113 Histone-fold

EC number: NA

Molecular weight: Translated: 7284; Mature: 7152

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELPIAPVGRIIKNAGAQRISDDAKEALAKALEEMGEEISRKAVELAKHAGRKTVKATD
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IEMAAKQL
HHHHHHCC
>Mature Secondary Structure 
AELPIAPVGRIIKNAGAQRISDDAKEALAKALEEMGEEISRKAVELAKHAGRKTVKATD
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IEMAAKQL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1459937; 9371463