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Identifier: 15678677

GI number: 15678677

Start: 575619

End: 576101

Strand: Direct

Name: Not Available

Synonym: MTH650

Alternate gene names: NA

Gene position: 575619-576101 (Clockwise)

Preceding gene: 15678668

Following gene: 15678678

Centisome position: 32.87

GC content: 51.14

Gene sequence:

>483_bases
GTGACTGTGAAGATCAGGAAGAGGTACCATATAAAGAAGAAGAAGCTCAGGGAGATACGGGGGCAGATTGGAGACTACTC
CTCCCTGATACCTGAAAAGGCCACGGTTGAAATCATTGAGACTGATGATAACAACATCATACTGGTTAATGGGGAGCCAC
TCCTCATGTTCATTGACGACAGGGTTGTCCCGACCCTGAGGGGCGCCCTGAAGATGGAAATAGATAGGGGATATGTGGTC
GTTGACATGGGGGCCGTCAGGTTCCTTGCAAACGGGGCCGATGTCATGAGCCCCGGTATAGTTGACGCCGACCCTGAGAT
ATCTGAGAACGACACCGTCGTTGTGGTGGATGAGAGAAACCGCAGACCCCTTGCAGTGGGTATAAGCCTCATAAGTGGAC
CTGAAATGGTTGAAAGAGATTCAGGAAAGGCTGTTAAGACCATCCACCACATCGGAGATGCCATCTGGGAACTGGAGGTC
TAG

Upstream 100 bases:

>100_bases
AAATGAGCTATAGATATACTTGCAGAAGAGTTTAAATGAGTCAATGATGGTAAAGCAGATTAAGGAACAGACTGCAGACC
ATTCATAAAATGAACAGGGT

Downstream 100 bases:

>100_bases
TGTTGGTTGAGCTGAACCTCGACGCCGGGAACATAATCTCAGAGGATGTCCACAGGATCGGGATACTGGCAGTGGGGTCA
CACCTCGAGAACCATGGCCC

Product: putative RNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTVKIRKRYHIKKKKLREIRGQIGDYSSLIPEKATVEIIETDDNNIILVNGEPLLMFIDDRVVPTLRGALKMEIDRGYVV
VDMGAVRFLANGADVMSPGIVDADPEISENDTVVVVDERNRRPLAVGISLISGPEMVERDSGKAVKTIHHIGDAIWELEV

Sequences:

>Translated_160_residues
MTVKIRKRYHIKKKKLREIRGQIGDYSSLIPEKATVEIIETDDNNIILVNGEPLLMFIDDRVVPTLRGALKMEIDRGYVV
VDMGAVRFLANGADVMSPGIVDADPEISENDTVVVVDERNRRPLAVGISLISGPEMVERDSGKAVKTIHHIGDAIWELEV
>Mature_159_residues
TVKIRKRYHIKKKKLREIRGQIGDYSSLIPEKATVEIIETDDNNIILVNGEPLLMFIDDRVVPTLRGALKMEIDRGYVVV
DMGAVRFLANGADVMSPGIVDADPEISENDTVVVVDERNRRPLAVGISLISGPEMVERDSGKAVKTIHHIGDAIWELEV

Specific function: Unknown

COG id: COG2016

COG function: function code J; Predicted RNA-binding protein (contains PUA domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PUA domain [H]

Homologues:

Organism=Homo sapiens, GI7662502, Length=157, Percent_Identity=27.3885350318471, Blast_Score=67, Evalue=8e-12,
Organism=Homo sapiens, GI212276121, Length=157, Percent_Identity=27.3885350318471, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25153759, Length=137, Percent_Identity=26.2773722627737, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320844, Length=139, Percent_Identity=31.6546762589928, Blast_Score=81, Evalue=9e-17,
Organism=Drosophila melanogaster, GI18858169, Length=135, Percent_Identity=31.1111111111111, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022430
- InterPro:   IPR015266
- InterPro:   IPR002478
- InterPro:   IPR015947
- InterPro:   IPR016437
- InterPro:   IPR004521 [H]

Pfam domain/function: PF01472 PUA [H]

EC number: NA

Molecular weight: Translated: 17831; Mature: 17700

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50890 PUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKIRKRYHIKKKKLREIRGQIGDYSSLIPEKATVEIIETDDNNIILVNGEPLLMFIDD
CEEEECHHHCHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCCEEEECCCEEEEEECC
RVVPTLRGALKMEIDRGYVVVDMGAVRFLANGADVMSPGIVDADPEISENDTVVVVDERN
CCCCHHCCEEEEEECCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
RRPLAVGISLISGPEMVERDSGKAVKTIHHIGDAIWELEV
CCEEEEEEEEECCCCCEECCCCCHHHHHHHHCCEEEEECC
>Mature Secondary Structure 
TVKIRKRYHIKKKKLREIRGQIGDYSSLIPEKATVEIIETDDNNIILVNGEPLLMFIDD
EEEECHHHCHHHHHHHHHHHCCCCHHHHCCCCCEEEEEEECCCCEEEECCCEEEEEECC
RVVPTLRGALKMEIDRGYVVVDMGAVRFLANGADVMSPGIVDADPEISENDTVVVVDERN
CCCCHHCCEEEEEECCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
RRPLAVGISLISGPEMVERDSGKAVKTIHHIGDAIWELEV
CCEEEEEEEEECCCCCEECCCCCHHHHHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]