| Definition | Methanothermobacter thermautotrophicus str. Delta H chromosome, complete genome. |
|---|---|
| Accession | NC_000916 |
| Length | 1,751,377 |
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Identifier: 15678647
GI number: 15678647
Start: 552991
End: 555240
Strand: Direct
Name: Not Available
Synonym: MTH619
Alternate gene names: 15678647
Gene position: 552991-555240 (Clockwise)
Preceding gene: 15678645
Following gene: 15678648
Centisome position: 31.57
GC content: 48.76
Gene sequence:
>2250_bases ATGGATAGGAACCTCAAGATATTCATAACGGTGATGTTAATTCTTTCAGTCATATCCCAGTTCCTGCCCTTTAAAAGGGA TGCTGTCTCACTTATAAACGTCATAACAAACCTTGCAGCCTTCATGGGACTTTCATATGCCTGCATATACTCCAGGAAGG TTTACCCGCACCTTTACCTCACGTTGCTCCTTCTATCCGCTGCCCAGTTCTTTTCATTCCTCGGAGACTTCACCTGGTTC ATACTTGAGAGTATACTGTCCCTGAATCCCTTCCCATCAGTTGCAGACCTGTTCTACCTCCTCTATTACCCCATCTTCGC AGCCGGCATATTCACAATACCCATCAAAAGATACTCTGACCTTAGATCAATCATAGACCTGCTGATAATCCTCGTGGCCT CTGCATCTGCCGCCTGGGTCTTCCTCCTTGAGCCCACAGTTTTTGCAGGAGGAGATTTCACAGAGGTCCTGGTATCAACA CTGTATGTCCTGGGCGATCTCCTCATAGTCTTCATGATAATGGACCTCATAATAAACAAGCTGGGGCACCTCAGATCAAG GACCCTCCACGTGTTCCTTGCAAGCATAATCATCCTCCTTGCAGCAGATATATCCTTCACATACCAGAACCTTACAGGAA TTTATGCTGGAGGAACACCCCAGGACCTCCTCTGGGCATTCAGTTACATTCTCCTCCTCATTGCAGTGAATGAATTCTTT AAGGAGGACTGGTCAAAGCCCTTATATGTTGAAAAAAAGGTCACAGCTGTCACATACACCCCCTATATCTTTATAATACT GTTCTATCTCTTAACGGCCTACAGCGTGATTAAGGGTGGTGCTGAAAAATCCACCGTGCTCTTAGTGTCCCTTGGATTCA TAATAGTCCTCTTCATTCTGAGGCAGCACCTTTCCATGAAGGAAAACATGGCCCTCCTCAATGATGTTGAGAATGAAAGG AGGAGGGCTGAAAATTACCTGGAGGTGGCGGGGTCCCTCATAATGGTCCTCGATGAGAAAACCCGTGTGAAGCTCATAAA CAGGAGGGGCCTTGAAATCCTTGAGTGTGACGCAGGGGAAGTCGCAGGGAAAAACTGGTTCATGACCTTCGTACCCCCTG AAGACAGGGGGTGGCGGGAAAAGCTATACACCGAAAAGATCAGCTCCGGGAGTAAGGGTTATCATCTGACCGGTGAGATA CTCACATGTAAGGGCGACAGGAAAACCGTCACATGGCACGTTGTATTCCTCAGGGAGGATGGTGAATTCAGGGGCAGCAT AATCTCAGGGGATGACATCACAGAACTCCAGAGAGCCACAAGGGCCCTCGAGATGAGTGAGATGAGGTACAGGGAGATAT TTGAACTCGCCCCTAGCCCGATAATATCGGTTGGTGATGACCTGATCATAAGGGACTGTAACAGGAGGGCTGAATCCGTT CTGGGCTACCAGAGAGGGGAGCTGATTGGAAGGAACCTGATGGACCTCATACACCCCGAGGATGCAGGAGAGGACTTTGA AGGGGAAAGAAGGCTCCTGAGATCAAATGGAGATGTCATATACGCCGATATAGGGGTCGCCCGGGTTGGGGATGAACGTA TAATCATAATCGAGGACCAGACAGAGATACGCAGGTCCCTCCAGGAGAAGGAACTCCTCCTGAGGGAGATACACCACCGG GTCAAGAACAACCTCCAGATAATATCAAGCCTGCTGAGCATACAGGAGCGTCAGCTGGAGTCAGAGGAACTTTCAGATGT CCTGAGAGAGAGCCGTGAGCGTATAAGGTCCATAGCCCTTGTCCATGAGCACCTCTACAGATCAACAAACCTCAGAACAA TAAGGATCAGGAATTACCTCAACAACATCCTCTCAAAGCTGAGCCAGGGACAGACCCATGGGAAGGATGTGAGGATCAGC TCCAGCATAGAGGACCTTGAATTCAACCTTGAGACCAGTCTCCCCATTGGTCTCATGGTCAACGAACTTGTGAGTAACTC CCTCAAGCACTCAGGGGCAGATAACATAACCGTTGAGCTCAGATCCCTCAACGGGACCCTTGAACTTACCGTGAAGGATG ATGGGATAGGCCTTGAATCACCGGAGGTCCTGGAGAAATCCGGAAGCATGGGCTGGTACCTTATACGGGCCCTGACAGAC CAGCTTGATGGTGAACTGAAAATAGAAACAGAGGATGGTCTATCTGTAAGTTTAAGGTTCAGGGAACTTGGATACAGAGA AAGGTACTGA
Upstream 100 bases:
>100_bases ATCAAGGTGTACATACACTTAAATGTTTCAGCTTCATGAATATTAATCAAGGTGTACATACACTCAAATTGTTTCATGAA TTATTAAATGGGGAGTCACG
Downstream 100 bases:
>100_bases GGGGATGGTTATGGAGTTCCGGATAACAGAGCGAGTACCGACTGCATCGCCTGGAATGTCCAGCCAGGATGCCCTCGAGA TGATAAGAAGGAAGATGGGC
Product: sensory transduction histidine kinase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 749; Mature: 749
Protein sequence:
>749_residues MDRNLKIFITVMLILSVISQFLPFKRDAVSLINVITNLAAFMGLSYACIYSRKVYPHLYLTLLLLSAAQFFSFLGDFTWF ILESILSLNPFPSVADLFYLLYYPIFAAGIFTIPIKRYSDLRSIIDLLIILVASASAAWVFLLEPTVFAGGDFTEVLVST LYVLGDLLIVFMIMDLIINKLGHLRSRTLHVFLASIIILLAADISFTYQNLTGIYAGGTPQDLLWAFSYILLLIAVNEFF KEDWSKPLYVEKKVTAVTYTPYIFIILFYLLTAYSVIKGGAEKSTVLLVSLGFIIVLFILRQHLSMKENMALLNDVENER RRAENYLEVAGSLIMVLDEKTRVKLINRRGLEILECDAGEVAGKNWFMTFVPPEDRGWREKLYTEKISSGSKGYHLTGEI LTCKGDRKTVTWHVVFLREDGEFRGSIISGDDITELQRATRALEMSEMRYREIFELAPSPIISVGDDLIIRDCNRRAESV LGYQRGELIGRNLMDLIHPEDAGEDFEGERRLLRSNGDVIYADIGVARVGDERIIIIEDQTEIRRSLQEKELLLREIHHR VKNNLQIISSLLSIQERQLESEELSDVLRESRERIRSIALVHEHLYRSTNLRTIRIRNYLNNILSKLSQGQTHGKDVRIS SSIEDLEFNLETSLPIGLMVNELVSNSLKHSGADNITVELRSLNGTLELTVKDDGIGLESPEVLEKSGSMGWYLIRALTD QLDGELKIETEDGLSVSLRFRELGYRERY
Sequences:
>Translated_749_residues MDRNLKIFITVMLILSVISQFLPFKRDAVSLINVITNLAAFMGLSYACIYSRKVYPHLYLTLLLLSAAQFFSFLGDFTWF ILESILSLNPFPSVADLFYLLYYPIFAAGIFTIPIKRYSDLRSIIDLLIILVASASAAWVFLLEPTVFAGGDFTEVLVST LYVLGDLLIVFMIMDLIINKLGHLRSRTLHVFLASIIILLAADISFTYQNLTGIYAGGTPQDLLWAFSYILLLIAVNEFF KEDWSKPLYVEKKVTAVTYTPYIFIILFYLLTAYSVIKGGAEKSTVLLVSLGFIIVLFILRQHLSMKENMALLNDVENER RRAENYLEVAGSLIMVLDEKTRVKLINRRGLEILECDAGEVAGKNWFMTFVPPEDRGWREKLYTEKISSGSKGYHLTGEI LTCKGDRKTVTWHVVFLREDGEFRGSIISGDDITELQRATRALEMSEMRYREIFELAPSPIISVGDDLIIRDCNRRAESV LGYQRGELIGRNLMDLIHPEDAGEDFEGERRLLRSNGDVIYADIGVARVGDERIIIIEDQTEIRRSLQEKELLLREIHHR VKNNLQIISSLLSIQERQLESEELSDVLRESRERIRSIALVHEHLYRSTNLRTIRIRNYLNNILSKLSQGQTHGKDVRIS SSIEDLEFNLETSLPIGLMVNELVSNSLKHSGADNITVELRSLNGTLELTVKDDGIGLESPEVLEKSGSMGWYLIRALTD QLDGELKIETEDGLSVSLRFRELGYRERY >Mature_749_residues MDRNLKIFITVMLILSVISQFLPFKRDAVSLINVITNLAAFMGLSYACIYSRKVYPHLYLTLLLLSAAQFFSFLGDFTWF ILESILSLNPFPSVADLFYLLYYPIFAAGIFTIPIKRYSDLRSIIDLLIILVASASAAWVFLLEPTVFAGGDFTEVLVST LYVLGDLLIVFMIMDLIINKLGHLRSRTLHVFLASIIILLAADISFTYQNLTGIYAGGTPQDLLWAFSYILLLIAVNEFF KEDWSKPLYVEKKVTAVTYTPYIFIILFYLLTAYSVIKGGAEKSTVLLVSLGFIIVLFILRQHLSMKENMALLNDVENER RRAENYLEVAGSLIMVLDEKTRVKLINRRGLEILECDAGEVAGKNWFMTFVPPEDRGWREKLYTEKISSGSKGYHLTGEI LTCKGDRKTVTWHVVFLREDGEFRGSIISGDDITELQRATRALEMSEMRYREIFELAPSPIISVGDDLIIRDCNRRAESV LGYQRGELIGRNLMDLIHPEDAGEDFEGERRLLRSNGDVIYADIGVARVGDERIIIIEDQTEIRRSLQEKELLLREIHHR VKNNLQIISSLLSIQERQLESEELSDVLRESRERIRSIALVHEHLYRSTNLRTIRIRNYLNNILSKLSQGQTHGKDVRIS SSIEDLEFNLETSLPIGLMVNELVSNSLKHSGADNITVELRSLNGTLELTVKDDGIGLESPEVLEKSGSMGWYLIRALTD QLDGELKIETEDGLSVSLRFRELGYRERY
Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 histidine kinase domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR022066 - InterPro: IPR011495 - InterPro: IPR005467 [H]
Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 85354; Mature: 85354
Theoretical pI: Translated: 5.25; Mature: 5.25
Prosite motif: PS50112 PAS ; PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDRNLKIFITVMLILSVISQFLPFKRDAVSLINVITNLAAFMGLSYACIYSRKVYPHLYL CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHH TLLLLSAAQFFSFLGDFTWFILESILSLNPFPSVADLFYLLYYPIFAAGIFTIPIKRYSD HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH LRSIIDLLIILVASASAAWVFLLEPTVFAGGDFTEVLVSTLYVLGDLLIVFMIMDLIINK HHHHHHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH LGHLRSRTLHVFLASIIILLAADISFTYQNLTGIYAGGTPQDLLWAFSYILLLIAVNEFF HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH KEDWSKPLYVEKKVTAVTYTPYIFIILFYLLTAYSVIKGGAEKSTVLLVSLGFIIVLFIL HHHCCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH RQHLSMKENMALLNDVENERRRAENYLEVAGSLIMVLDEKTRVKLINRRGLEILECDAGE HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCEEEECCCCC VAGKNWFMTFVPPEDRGWREKLYTEKISSGSKGYHLTGEILTCKGDRKTVTWHVVFLRED CCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEECEEEEECCCCEEEEEEEEEEEEC GEFRGSIISGDDITELQRATRALEMSEMRYREIFELAPSPIISVGDDLIIRDCNRRAESV CCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH LGYQRGELIGRNLMDLIHPEDAGEDFEGERRLLRSNGDVIYADIGVARVGDERIIIIEDQ HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEECCEEEECCCEEEEEECH TEIRRSLQEKELLLREIHHRVKNNLQIISSLLSIQERQLESEELSDVLRESRERIRSIAL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH VHEHLYRSTNLRTIRIRNYLNNILSKLSQGQTHGKDVRISSSIEDLEFNLETSLPIGLMV HHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHEECCCCCCCHHHHH NELVSNSLKHSGADNITVELRSLNGTLELTVKDDGIGLESPEVLEKSGSMGWYLIRALTD HHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHH QLDGELKIETEDGLSVSLRFRELGYRERY HCCCCEEEEECCCCEEEEEEHHCCCCCCC >Mature Secondary Structure MDRNLKIFITVMLILSVISQFLPFKRDAVSLINVITNLAAFMGLSYACIYSRKVYPHLYL CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHH TLLLLSAAQFFSFLGDFTWFILESILSLNPFPSVADLFYLLYYPIFAAGIFTIPIKRYSD HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH LRSIIDLLIILVASASAAWVFLLEPTVFAGGDFTEVLVSTLYVLGDLLIVFMIMDLIINK HHHHHHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH LGHLRSRTLHVFLASIIILLAADISFTYQNLTGIYAGGTPQDLLWAFSYILLLIAVNEFF HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH KEDWSKPLYVEKKVTAVTYTPYIFIILFYLLTAYSVIKGGAEKSTVLLVSLGFIIVLFIL HHHCCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH RQHLSMKENMALLNDVENERRRAENYLEVAGSLIMVLDEKTRVKLINRRGLEILECDAGE HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCEEEECCCCC VAGKNWFMTFVPPEDRGWREKLYTEKISSGSKGYHLTGEILTCKGDRKTVTWHVVFLRED CCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEECEEEEECCCCEEEEEEEEEEEEC GEFRGSIISGDDITELQRATRALEMSEMRYREIFELAPSPIISVGDDLIIRDCNRRAESV CCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH LGYQRGELIGRNLMDLIHPEDAGEDFEGERRLLRSNGDVIYADIGVARVGDERIIIIEDQ HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEECCEEEECCCEEEEEECH TEIRRSLQEKELLLREIHHRVKNNLQIISSLLSIQERQLESEELSDVLRESRERIRSIAL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH VHEHLYRSTNLRTIRIRNYLNNILSKLSQGQTHGKDVRISSSIEDLEFNLETSLPIGLMV HHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCEEECCCHHHHEECCCCCCCHHHHH NELVSNSLKHSGADNITVELRSLNGTLELTVKDDGIGLESPEVLEKSGSMGWYLIRALTD HHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHH QLDGELKIETEDGLSVSLRFRELGYRERY HCCCCEEEEECCCCEEEEEEHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]