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Identifier: 15678634

GI number: 15678634

Start: 542052

End: 542861

Strand: Direct

Name: Not Available

Synonym: MTH606

Alternate gene names: 15678634

Gene position: 542052-542861 (Clockwise)

Preceding gene: 15678633

Following gene: 15678635

Centisome position: 30.95

GC content: 51.6

Gene sequence:

>810_bases
GTGATGGGCTTGCTGGAGTTGCTGCAGTACCAGTTCATGAGGAACGCGGCTGTCGCAGCCATACTTGTAAGTATAGCTTG
CGGTGCAGTTGGGAGCTACGTTGTAACAAAGAGGATAGTGTCAATAAGTGGCGGCATATCCCATGCAGCCTTTGGTGGCG
TGGGCCTCGGCTACTTCCTCGGGGTGAACCCGATCACATCTGCCATACCCTTCACGGTGGCTGCAGCCCTTACGATGGGT
GCAGTGACACGGAGGACCCGTATAAGTGAGGACACTGCAATAGGGGTGCTCTGGTCCGCAGGGATGGCCCTGGGTATACT
TTTCATAAACCTCAGCCCGGGCTATGCACCGGACCTCTTCAGCTACCTCTTCGGTAACATACTCATGGTAGACAACGGGG
ACCTCTGGACCATGCTGGTGCTTGACCTCATCATAATATCAAGTGCCCTCCTGTTCAACAGGGAGTTCGTTGCCATCTGC
TTTGATGAGGAGTACGCCGAGGTTCTGGGTGTCCCTGTCGACGCCTTCTACCTGTACCTCCTTGTCCTTGTTGCCATAAG
TGTTGTGGTTCTCATAAAGGCTGCCGGAATAATACTTGTGATGGCCCTCCTAACAATCCCTGCAGCACTTGCAAAGGATT
TCAGTTCAGATATGGCTGATATAATGGTTAAGGCATCGGCTATAGGTATAATCACGGCCCTCGCAGGCCTCTGGATCTCA
TATATATTCAACGTATCTTCAGGTGCAGTTATAGTGCTGGTCCTCACAGCTCTCTTTGGTGCTGTTCAGTTCATCAAAAG
ACGGTTTTGA

Upstream 100 bases:

>100_bases
GAAATGCTGAATTCCCGGTATCCGAGTACAATGAGAAGATGACAGCATCAGCTGAATCACAGATACTGAATCCTTATGAC
GTGAACGATCCAAGGAAGGA

Downstream 100 bases:

>100_bases
TTACATTTGAACTGATTGGCCTTAAAAGGGTATGAAGCCAATAAATACATTAAAGATGGTGCAGAACACTAGAACATGAA
GTGCGGATCTGACCTCAGGG

Product: manganese transport system membrane protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MMGLLELLQYQFMRNAAVAAILVSIACGAVGSYVVTKRIVSISGGISHAAFGGVGLGYFLGVNPITSAIPFTVAAALTMG
AVTRRTRISEDTAIGVLWSAGMALGILFINLSPGYAPDLFSYLFGNILMVDNGDLWTMLVLDLIIISSALLFNREFVAIC
FDEEYAEVLGVPVDAFYLYLLVLVAISVVVLIKAAGIILVMALLTIPAALAKDFSSDMADIMVKASAIGIITALAGLWIS
YIFNVSSGAVIVLVLTALFGAVQFIKRRF

Sequences:

>Translated_269_residues
MMGLLELLQYQFMRNAAVAAILVSIACGAVGSYVVTKRIVSISGGISHAAFGGVGLGYFLGVNPITSAIPFTVAAALTMG
AVTRRTRISEDTAIGVLWSAGMALGILFINLSPGYAPDLFSYLFGNILMVDNGDLWTMLVLDLIIISSALLFNREFVAIC
FDEEYAEVLGVPVDAFYLYLLVLVAISVVVLIKAAGIILVMALLTIPAALAKDFSSDMADIMVKASAIGIITALAGLWIS
YIFNVSSGAVIVLVLTALFGAVQFIKRRF
>Mature_269_residues
MMGLLELLQYQFMRNAAVAAILVSIACGAVGSYVVTKRIVSISGGISHAAFGGVGLGYFLGVNPITSAIPFTVAAALTMG
AVTRRTRISEDTAIGVLWSAGMALGILFINLSPGYAPDLFSYLFGNILMVDNGDLWTMLVLDLIIISSALLFNREFVAIC
FDEEYAEVLGVPVDAFYLYLLVLVAISVVVLIKAAGIILVMALLTIPAALAKDFSSDMADIMVKASAIGIITALAGLWIS
YIFNVSSGAVIVLVLTALFGAVQFIKRRF

Specific function: Involved In The High-Affinity Zinc Uptake Transport System. [C]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=242, Percent_Identity=28.099173553719, Blast_Score=101, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 28505; Mature: 28505

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGLLELLQYQFMRNAAVAAILVSIACGAVGSYVVTKRIVSISGGISHAAFGGVGLGYFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHH
GVNPITSAIPFTVAAALTMGAVTRRTRISEDTAIGVLWSAGMALGILFINLSPGYAPDLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHH
SYLFGNILMVDNGDLWTMLVLDLIIISSALLFNREFVAICFDEEYAEVLGVPVDAFYLYL
HHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCHHHHHHHH
LVLVAISVVVLIKAAGIILVMALLTIPAALAKDFSSDMADIMVKASAIGIITALAGLWIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIFNVSSGAVIVLVLTALFGAVQFIKRRF
HHHHCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMGLLELLQYQFMRNAAVAAILVSIACGAVGSYVVTKRIVSISGGISHAAFGGVGLGYFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHH
GVNPITSAIPFTVAAALTMGAVTRRTRISEDTAIGVLWSAGMALGILFINLSPGYAPDLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHH
SYLFGNILMVDNGDLWTMLVLDLIIISSALLFNREFVAICFDEEYAEVLGVPVDAFYLYL
HHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCHHHHHHHH
LVLVAISVVVLIKAAGIILVMALLTIPAALAKDFSSDMADIMVKASAIGIITALAGLWIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIFNVSSGAVIVLVLTALFGAVQFIKRRF
HHHHCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]