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Identifier: 15678485

GI number: 15678485

Start: 397168

End: 398946

Strand: Direct

Name: Not Available

Synonym: MTH457

Alternate gene names: 15678485

Gene position: 397168-398946 (Clockwise)

Preceding gene: 15678484

Following gene: 15678486

Centisome position: 22.68

GC content: 52.56

Gene sequence:

>1779_bases
ATGCCATCTGCCCTTGTCGTCGAGGACGAGGCTGTAACCTCCCTTGAACTTTTAAGGCTCCTGGAATCCTGGGGGTATGA
AACGGTCAGTGTAAAGACCGGGGAGGATGCCATTGAAACCGCGCTGAGGATGAAACCCGACGTCATCCTCATGGACATAG
TACTCCCCTCAGATGTGGATGGAGTCACAGCAGCAAGGGCCATAAAGAAGGAGATGGACATCCCCCTGATTTTCATAACA
GCCTACTCCAGCAGGGAGGTATTTGAGAGGGCAGCCGAGGTTGAACCTGAGGCCTACCTCCTCAAGCCCTTCAACTCCCG
GGAACTTGGATATGCAATGGAACTTGCAATCTACAAGAACCGGATCCAGAACCTGCTCTCACATACCAGCAGGAGGTACC
AGGAGATACTGGAAACCACAGGTGAGGGTGTCTGCGTATTCAATGACGATGGAAGCATCCAGTACTGCAATGAGAGGATG
GCTGACCTCCTCTCCATGAGAAGGGACGAGATTATCGGAAGGAAGATATTCGATTTTATACATCCCTCTGACCGGGAGAC
CATGGAGCGAATACTTGATTCATGCAGAAGGGGATCCTCGGGTGAACATGAACTCCGCTTCAGGACGGATGAGGGGACAA
GGTGGGTGATACTCTCAGGTCATCCCCTCATTGAATCCTCCGGCTTCAGGGGAGGATTCTGCATGTTCAGGGATATAACG
CCCCAGAAGATGCTTGAAAGGATGCTGAGGAGAAACAACAGCTGCCTCAGACTTCTAAGCAGGATCAACCGCCAGGCAGC
CATCTCAGCCACCCCTCAGGAATTGATGGAAGGGGTTTCCGGGATCCTGATGGAGGTCGGATACTCCGGTGCATCCTTCA
GGGAATCTGATGGAACCGTGATTGCAGGGGAGGGTGAAAAAAGAGTATCACCACTCCGGCCAGGCATCATCACCTGGGAG
GATACCTCAACTGCAGTCATTGAACTTGAAGATTGCAGCAAACCCCTTTACCTTGTGGTCTCAGCCCCCAGGATGATTGA
CGATGAGGAGCTGGGCTTCCTCAGGGAGATAGCATCCAGCACAGCCGGTGCCCTCAGGAGGATGGACTCTGAGCAGAGGA
TGAATGATATTTCCTCAAGGTACCGGGAACTCTTTGAGAATGCAGGGGATGCGATATTCCTGGTGAAGGACTTCAGGATA
ATAGGATGTAACAGCAGGGCCCTTGAACTCTTCGGGGGAGATGAGGAAGACATACTGGGCAGAAAACCATGGGAGCTATC
ACCTGAGTACCAGCACCATGGTGAATCCTCAGAAATTGCCCGGGAACTTATTGAGAGGGCAATGAATGGCGAAAAATGCG
AGTTCACATGGATCCACAGAAAGATCAGCGGTGAGACATTCCCGACAAGGGTGGTCCTCAGCAGATCAGGTGACATTGTG
ATGGGCATTGTCAGGGACATGACTGAACTCTACAGGGCCCACAGGAAGTTAAAGGAGGAGCACAGAAAGTTCAGGGACCT
GCTGGAGTCCATACCCGACCCTACCTTCGCCCTGGATACCCGTGGAAGGGTGATAGCCTGGAACCGTGAGATTGAGAGAC
TCACAGGTGTGAAAAAGGAAGAGATCCTCGGGAGGGGTAACAGGGTCTACGCAGTTCCGTTCTATGGCAGGAGGACGCCG
GGGCTCCTTGAATTCCTGCTGAACCCTGGAAAGGCCCCTTCAAGGTACCGCAACATCAGCAGGGAGGGTAATGCAATCTA
TGCAGAGGTCCATGTTTAG

Upstream 100 bases:

>100_bases
ACCACTGCACACATAATCAACCACATGGTTTACAGATATACATTCAACTTTTTTCTTTCAATAAAAAAATTAATATAACA
GAAAAAATAATATAATATCC

Downstream 100 bases:

>100_bases
CACATGGGCAGGCACTTCCAGCTCAAGGCATCCCCGATCTGTGATGCGGAGGATAGAACCGTGGGGGCCATAGAGATACT
GAGGGACGTTACAGATTACA

Product: sensory transduction regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MPSALVVEDEAVTSLELLRLLESWGYETVSVKTGEDAIETALRMKPDVILMDIVLPSDVDGVTAARAIKKEMDIPLIFIT
AYSSREVFERAAEVEPEAYLLKPFNSRELGYAMELAIYKNRIQNLLSHTSRRYQEILETTGEGVCVFNDDGSIQYCNERM
ADLLSMRRDEIIGRKIFDFIHPSDRETMERILDSCRRGSSGEHELRFRTDEGTRWVILSGHPLIESSGFRGGFCMFRDIT
PQKMLERMLRRNNSCLRLLSRINRQAAISATPQELMEGVSGILMEVGYSGASFRESDGTVIAGEGEKRVSPLRPGIITWE
DTSTAVIELEDCSKPLYLVVSAPRMIDDEELGFLREIASSTAGALRRMDSEQRMNDISSRYRELFENAGDAIFLVKDFRI
IGCNSRALELFGGDEEDILGRKPWELSPEYQHHGESSEIARELIERAMNGEKCEFTWIHRKISGETFPTRVVLSRSGDIV
MGIVRDMTELYRAHRKLKEEHRKFRDLLESIPDPTFALDTRGRVIAWNREIERLTGVKKEEILGRGNRVYAVPFYGRRTP
GLLEFLLNPGKAPSRYRNISREGNAIYAEVHV

Sequences:

>Translated_592_residues
MPSALVVEDEAVTSLELLRLLESWGYETVSVKTGEDAIETALRMKPDVILMDIVLPSDVDGVTAARAIKKEMDIPLIFIT
AYSSREVFERAAEVEPEAYLLKPFNSRELGYAMELAIYKNRIQNLLSHTSRRYQEILETTGEGVCVFNDDGSIQYCNERM
ADLLSMRRDEIIGRKIFDFIHPSDRETMERILDSCRRGSSGEHELRFRTDEGTRWVILSGHPLIESSGFRGGFCMFRDIT
PQKMLERMLRRNNSCLRLLSRINRQAAISATPQELMEGVSGILMEVGYSGASFRESDGTVIAGEGEKRVSPLRPGIITWE
DTSTAVIELEDCSKPLYLVVSAPRMIDDEELGFLREIASSTAGALRRMDSEQRMNDISSRYRELFENAGDAIFLVKDFRI
IGCNSRALELFGGDEEDILGRKPWELSPEYQHHGESSEIARELIERAMNGEKCEFTWIHRKISGETFPTRVVLSRSGDIV
MGIVRDMTELYRAHRKLKEEHRKFRDLLESIPDPTFALDTRGRVIAWNREIERLTGVKKEEILGRGNRVYAVPFYGRRTP
GLLEFLLNPGKAPSRYRNISREGNAIYAEVHV
>Mature_591_residues
PSALVVEDEAVTSLELLRLLESWGYETVSVKTGEDAIETALRMKPDVILMDIVLPSDVDGVTAARAIKKEMDIPLIFITA
YSSREVFERAAEVEPEAYLLKPFNSRELGYAMELAIYKNRIQNLLSHTSRRYQEILETTGEGVCVFNDDGSIQYCNERMA
DLLSMRRDEIIGRKIFDFIHPSDRETMERILDSCRRGSSGEHELRFRTDEGTRWVILSGHPLIESSGFRGGFCMFRDITP
QKMLERMLRRNNSCLRLLSRINRQAAISATPQELMEGVSGILMEVGYSGASFRESDGTVIAGEGEKRVSPLRPGIITWED
TSTAVIELEDCSKPLYLVVSAPRMIDDEELGFLREIASSTAGALRRMDSEQRMNDISSRYRELFENAGDAIFLVKDFRII
GCNSRALELFGGDEEDILGRKPWELSPEYQHHGESSEIARELIERAMNGEKCEFTWIHRKISGETFPTRVVLSRSGDIVM
GIVRDMTELYRAHRKLKEEHRKFRDLLESIPDPTFALDTRGRVIAWNREIERLTGVKKEEILGRGNRVYAVPFYGRRTPG
LLEFLLNPGKAPSRYRNISREGNAIYAEVHV

Specific function: Member of the two-component regulatory system pdtaR/pdtaS [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005561
- InterPro:   IPR011006
- InterPro:   IPR008327
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03861 ANTAR; PF00072 Response_reg [H]

EC number: 2.7.3.-

Molecular weight: Translated: 67457; Mature: 67326

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSALVVEDEAVTSLELLRLLESWGYETVSVKTGEDAIETALRMKPDVILMDIVLPSDVD
CCCCEEECCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCC
GVTAARAIKKEMDIPLIFITAYSSREVFERAAEVEPEAYLLKPFNSRELGYAMELAIYKN
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHH
RIQNLLSHTSRRYQEILETTGEGVCVFNDDGSIQYCNERMADLLSMRRDEIIGRKIFDFI
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
HPSDRETMERILDSCRRGSSGEHELRFRTDEGTRWVILSGHPLIESSGFRGGFCMFRDIT
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCEECCCCCCCCEEEEECCC
PQKMLERMLRRNNSCLRLLSRINRQAAISATPQELMEGVSGILMEVGYSGASFRESDGTV
HHHHHHHHHHCCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
IAGEGEKRVSPLRPGIITWEDTSTAVIELEDCSKPLYLVVSAPRMIDDEELGFLREIASS
EECCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
TAGALRRMDSEQRMNDISSRYRELFENAGDAIFLVKDFRIIGCNSRALELFGGDEEDILG
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEECCCCCHHHCC
RKPWELSPEYQHHGESSEIARELIERAMNGEKCEFTWIHRKISGETFPTRVVLSRSGDIV
CCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEEECCCCEE
MGIVRDMTELYRAHRKLKEEHRKFRDLLESIPDPTFALDTRGRVIAWNREIERLTGVKKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCHHHHHHCCCHH
EILGRGNRVYAVPFYGRRTPGLLEFLLNPGKAPSRYRNISREGNAIYAEVHV
HHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEC
>Mature Secondary Structure 
PSALVVEDEAVTSLELLRLLESWGYETVSVKTGEDAIETALRMKPDVILMDIVLPSDVD
CCCEEECCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCC
GVTAARAIKKEMDIPLIFITAYSSREVFERAAEVEPEAYLLKPFNSRELGYAMELAIYKN
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHH
RIQNLLSHTSRRYQEILETTGEGVCVFNDDGSIQYCNERMADLLSMRRDEIIGRKIFDFI
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
HPSDRETMERILDSCRRGSSGEHELRFRTDEGTRWVILSGHPLIESSGFRGGFCMFRDIT
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCEECCCCCCCCEEEEECCC
PQKMLERMLRRNNSCLRLLSRINRQAAISATPQELMEGVSGILMEVGYSGASFRESDGTV
HHHHHHHHHHCCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
IAGEGEKRVSPLRPGIITWEDTSTAVIELEDCSKPLYLVVSAPRMIDDEELGFLREIASS
EECCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
TAGALRRMDSEQRMNDISSRYRELFENAGDAIFLVKDFRIIGCNSRALELFGGDEEDILG
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEECCCCCHHHCC
RKPWELSPEYQHHGESSEIARELIERAMNGEKCEFTWIHRKISGETFPTRVVLSRSGDIV
CCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEEECCCCEE
MGIVRDMTELYRAHRKLKEEHRKFRDLLESIPDPTFALDTRGRVIAWNREIERLTGVKKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCHHHHHHCCCHH
EILGRGNRVYAVPFYGRRTPGLLEFLLNPGKAPSRYRNISREGNAIYAEVHV
HHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]