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Identifier: 15678406

GI number: 15678406

Start: 323319

End: 324323

Strand: Direct

Name: Not Available

Synonym: MTH378

Alternate gene names: NA

Gene position: 323319-324323 (Clockwise)

Preceding gene: 15678405

Following gene: 15678412

Centisome position: 18.46

GC content: 50.35

Gene sequence:

>1005_bases
ATGGACTCCATGAAAAGGTTTTACTTCTTTGCACTGAGCATCCTTCTCATCCTGGCACTCATAATATGGATGGGACCCTC
AAGGATCATCAGGGCAGTCTACATGGCGGACTGGATGATCATAGCCATCGCACTTCTCATCCACATGGGGGTTCTGGCTG
TTAGGGGCCTCCGCTGGGGTTTCATTATAGGCCAGCCCTGGAGGATGCGGGTCAACTTCATGGTGAAGACCATCGGCCTC
TTTGCCGGTAACCTCAGCCCCATGAGGAGTGCTGGCGAGGTCATGAATGCACTAGCAGGTAAAAAACTGAACGGAATTGA
ACTCTCAGAGGGTCTCTCAGCTGGTTTAACCGAGAGGTTCTTTGATCTGGGGATAGGAGGGGGTCTGCTTCTCCTTGCAG
CCGTGATGGTGCCGGTGATAAGGGTAATAGCCCTCTTCGGGGCGATTCTATCTGTCCTCATAACCTACCTCATCTACCTT
GTTAACTGGAGGGAGGAGAAGGGTTTGAGGATCTACCAGAGGATACATAGCATCATTGAGAGACTTCCAGTATCTGAGGA
AACACTTGAAAACCTCTATGAACGTTTAACCTCCGGTATAAAGGGCATGATAGGTTACACGAGATCCTACTCCAACTTCA
CCTCCCTTGGAGTCATATTCATCCTTTCACTCCTCTCCTGGCTCATGGAGTGCCTGAGACTCTACCTGGTATTCATGGCC
TTCGGAGTGGAGACCTCCTTCTCTGCAGTTATAATAATATTCCTCCTGGCAAACCTTGTGGGCATACTATCTGCCCTTCC
AGGGGGCATGGGCTCAATGGAGGTCTCAATGGCAGGACTGTTTGTAGTATTTGGTGTCCCCGGGTTCCTGGCTGGAAGCA
TAGCCCTGGTGGACCGTATAATATCATTCTGGATGGTCACAGCACTGGGAGCCATCTTCTCATCCTGCTATGCCGGGGAG
ATATTTGATGAGGTCAGGTCCTATATCCTTGATATAAGGGCGTGA

Upstream 100 bases:

>100_bases
CAGTACATCAGGTTCATAGTTAGGCTCTTCGTCAGAAGGATATCCGGTGTCAGGGGCTGATGTGGGAGCTGCTTCCCATC
ACCTTCACATCTGAGAGGAG

Downstream 100 bases:

>100_bases
TGAGGGGCTTTGTGATGTATTTCTGATAGTCCTGTTTTTTTGGAGGTCATATATCCTGATGAACTGATTTTTATCTCTGG
CCCCTGATGATTGACCTCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MDSMKRFYFFALSILLILALIIWMGPSRIIRAVYMADWMIIAIALLIHMGVLAVRGLRWGFIIGQPWRMRVNFMVKTIGL
FAGNLSPMRSAGEVMNALAGKKLNGIELSEGLSAGLTERFFDLGIGGGLLLLAAVMVPVIRVIALFGAILSVLITYLIYL
VNWREEKGLRIYQRIHSIIERLPVSEETLENLYERLTSGIKGMIGYTRSYSNFTSLGVIFILSLLSWLMECLRLYLVFMA
FGVETSFSAVIIIFLLANLVGILSALPGGMGSMEVSMAGLFVVFGVPGFLAGSIALVDRIISFWMVTALGAIFSSCYAGE
IFDEVRSYILDIRA

Sequences:

>Translated_334_residues
MDSMKRFYFFALSILLILALIIWMGPSRIIRAVYMADWMIIAIALLIHMGVLAVRGLRWGFIIGQPWRMRVNFMVKTIGL
FAGNLSPMRSAGEVMNALAGKKLNGIELSEGLSAGLTERFFDLGIGGGLLLLAAVMVPVIRVIALFGAILSVLITYLIYL
VNWREEKGLRIYQRIHSIIERLPVSEETLENLYERLTSGIKGMIGYTRSYSNFTSLGVIFILSLLSWLMECLRLYLVFMA
FGVETSFSAVIIIFLLANLVGILSALPGGMGSMEVSMAGLFVVFGVPGFLAGSIALVDRIISFWMVTALGAIFSSCYAGE
IFDEVRSYILDIRA
>Mature_334_residues
MDSMKRFYFFALSILLILALIIWMGPSRIIRAVYMADWMIIAIALLIHMGVLAVRGLRWGFIIGQPWRMRVNFMVKTIGL
FAGNLSPMRSAGEVMNALAGKKLNGIELSEGLSAGLTERFFDLGIGGGLLLLAAVMVPVIRVIALFGAILSVLITYLIYL
VNWREEKGLRIYQRIHSIIERLPVSEETLENLYERLTSGIKGMIGYTRSYSNFTSLGVIFILSLLSWLMECLRLYLVFMA
FGVETSFSAVIIIFLLANLVGILSALPGGMGSMEVSMAGLFVVFGVPGFLAGSIALVDRIISFWMVTALGAIFSSCYAGE
IFDEVRSYILDIRA

Specific function: Unknown

COG id: COG0392

COG function: function code S; Predicted integral membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0104 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y378_METTH (O26478)

Other databases:

- EMBL:   AE000666
- PIR:   H69148
- RefSeq:   NP_275521.1
- STRING:   O26478
- GeneID:   1470339
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH378
- NMPDR:   fig|187420.1.peg.376
- eggNOG:   arNOG18224
- OMA:   ELMRIRY
- BioCyc:   MTHE187420:MTH378-MONOMER
- InterPro:   IPR022791
- InterPro:   IPR005242
- TIGRFAMs:   TIGR00374

Pfam domain/function: PF03706 UPF0104

EC number: NA

Molecular weight: Translated: 36960; Mature: 36960

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf6cdef0)-; HASH(0xef74374)-; HASH(0xfa9e060)-; HASH(0xf9be0f8)-; HASH(0xf0c204c)-; HASH(0xf09a818)-; HASH(0xf855198)-; HASH(0xf35e854)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSMKRFYFFALSILLILALIIWMGPSRIIRAVYMADWMIIAIALLIHMGVLAVRGLRWG
CCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FIIGQPWRMRVNFMVKTIGLFAGNLSPMRSAGEVMNALAGKKLNGIELSEGLSAGLTERF
EEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHCHHHHHHHHH
FDLGIGGGLLLLAAVMVPVIRVIALFGAILSVLITYLIYLVNWREEKGLRIYQRIHSIIE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHH
RLPVSEETLENLYERLTSGIKGMIGYTRSYSNFTSLGVIFILSLLSWLMECLRLYLVFMA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGVETSFSAVIIIFLLANLVGILSALPGGMGSMEVSMAGLFVVFGVPGFLAGSIALVDRI
HCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ISFWMVTALGAIFSSCYAGEIFDEVRSYILDIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MDSMKRFYFFALSILLILALIIWMGPSRIIRAVYMADWMIIAIALLIHMGVLAVRGLRWG
CCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FIIGQPWRMRVNFMVKTIGLFAGNLSPMRSAGEVMNALAGKKLNGIELSEGLSAGLTERF
EEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHCHHHHHHHHH
FDLGIGGGLLLLAAVMVPVIRVIALFGAILSVLITYLIYLVNWREEKGLRIYQRIHSIIE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHH
RLPVSEETLENLYERLTSGIKGMIGYTRSYSNFTSLGVIFILSLLSWLMECLRLYLVFMA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGVETSFSAVIIIFLLANLVGILSALPGGMGSMEVSMAGLFVVFGVPGFLAGSIALVDRI
HCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ISFWMVTALGAIFSSCYAGEIFDEVRSYILDIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371463