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Identifier: 15678363

GI number: 15678363

Start: 270853

End: 271974

Strand: Direct

Name: Not Available

Synonym: MTH335

Alternate gene names: 15678363

Gene position: 270853-271974 (Clockwise)

Preceding gene: 15678362

Following gene: 15678364

Centisome position: 15.47

GC content: 35.38

Gene sequence:

>1122_bases
ATGAAAATAGCGTTTTTTCATCATACCATGGTCAGAGGTAGTGGAATAGATACTGTGATATGGGAACTTGCAAAAAGACT
GAAAAAAGATCATGATGTGAGTATCTTCACATTTTTCAATGAATATGACAACCCCATTGTTAACACTATCTCTATTCCAT
TCCATGAAAACCGTCTTGTTAATGCAGTTTTTGCACCAATCATACCTAGTTCTTATAGCTTCAGAAAAAAGGTTAAGGAT
TTTGATGTTGTAAACGTTCACCATTTCCCTGCCAACTTTTTTCCATTCTTTCCTACCAATATGGATACTCTCAATATCGT
GACAGAATGGAGCGGTCCTCCTATGTGTTTACTTGAAAACATGAATTTCAATGAAAGATTATACATGAAATTAGCCCGCT
TCATGAATAAATATGCTGCAAATCGTGCCGATGGGTTGTTAGCGCCATGTAGTTTTGTTAAACAATGGATAATGGATAAC
TATGGTCTTAATTCCCATAAGATGTATCTGGATGGAATAAACTTTGATTATTTTGATTACAGAAATGAGTATAATAAACC
TGATTTTGGAGGTCCTACCATACTTTACGTGGGGCGTATTGCACCAAACAAAAATATTGATCTTTTAATAGAATCCTTTG
AAATCGTGAAAAAGGAATTTGATGATTCTAAACTTGTTATCGTGGGTCGCAAAACATTCCCTGCTTATTATCGGAAGCTT
AAAAAAGTTATAAAAAACAAAAATCTCCAGGAGGATGTTATATTCACAGGAGAAGTTCCCTGGGGAGAATTACCAGATTA
TTATGCATCATGTGACGTTTATGCTACATGTTCATCGTGGGAGGGATTCCTCAGGGCCGAGGCTTTTGCAATGAAGAAAC
CCATGGTAGCATTTGATACGGGTGCAAATAGAGATACCATAAAGGACGGTATAAATGGATTTCTGGTTGAAAATGGAGAT
TATGTATCATTTGCAGAAGCTATAATAAAATTAATCGAGGATCCTACTTTAAATAAGCATATGGGTAATGAAGGATATAG
ATGGGCACGTAAACATCTAGATTTTGATGTAATCTGCCAAAATTTCTCTAAATATCTTGAGGAGGAGATTTCTTGCAGAT
AA

Upstream 100 bases:

>100_bases
CAGAAAACCTCTCTTATGGTGGTCTGAGTCTTCCATCAAGTGTTGAAATTGGAGATGAAGCCATAGAATACGTTGTTGAT
AGAGTAAGGGAGTTTTTTGA

Downstream 100 bases:

>100_bases
GGATGGTTAAAATGTCTGATGTATGGTCTCTTACTAACTTTTACATGTCTCTAAAAGAAAACGAAAGAATCTTATTCCAC
CCATTCCCTTTTAGATACCC

Product: galactosyl-transferase RfpB related protein

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKIAFFHHTMVRGSGIDTVIWELAKRLKKDHDVSIFTFFNEYDNPIVNTISIPFHENRLVNAVFAPIIPSSYSFRKKVKD
FDVVNVHHFPANFFPFFPTNMDTLNIVTEWSGPPMCLLENMNFNERLYMKLARFMNKYAANRADGLLAPCSFVKQWIMDN
YGLNSHKMYLDGINFDYFDYRNEYNKPDFGGPTILYVGRIAPNKNIDLLIESFEIVKKEFDDSKLVIVGRKTFPAYYRKL
KKVIKNKNLQEDVIFTGEVPWGELPDYYASCDVYATCSSWEGFLRAEAFAMKKPMVAFDTGANRDTIKDGINGFLVENGD
YVSFAEAIIKLIEDPTLNKHMGNEGYRWARKHLDFDVICQNFSKYLEEEISCR

Sequences:

>Translated_373_residues
MKIAFFHHTMVRGSGIDTVIWELAKRLKKDHDVSIFTFFNEYDNPIVNTISIPFHENRLVNAVFAPIIPSSYSFRKKVKD
FDVVNVHHFPANFFPFFPTNMDTLNIVTEWSGPPMCLLENMNFNERLYMKLARFMNKYAANRADGLLAPCSFVKQWIMDN
YGLNSHKMYLDGINFDYFDYRNEYNKPDFGGPTILYVGRIAPNKNIDLLIESFEIVKKEFDDSKLVIVGRKTFPAYYRKL
KKVIKNKNLQEDVIFTGEVPWGELPDYYASCDVYATCSSWEGFLRAEAFAMKKPMVAFDTGANRDTIKDGINGFLVENGD
YVSFAEAIIKLIEDPTLNKHMGNEGYRWARKHLDFDVICQNFSKYLEEEISCR
>Mature_373_residues
MKIAFFHHTMVRGSGIDTVIWELAKRLKKDHDVSIFTFFNEYDNPIVNTISIPFHENRLVNAVFAPIIPSSYSFRKKVKD
FDVVNVHHFPANFFPFFPTNMDTLNIVTEWSGPPMCLLENMNFNERLYMKLARFMNKYAANRADGLLAPCSFVKQWIMDN
YGLNSHKMYLDGINFDYFDYRNEYNKPDFGGPTILYVGRIAPNKNIDLLIESFEIVKKEFDDSKLVIVGRKTFPAYYRKL
KKVIKNKNLQEDVIFTGEVPWGELPDYYASCDVYATCSSWEGFLRAEAFAMKKPMVAFDTGANRDTIKDGINGFLVENGD
YVSFAEAIIKLIEDPTLNKHMGNEGYRWARKHLDFDVICQNFSKYLEEEISCR

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose resid

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI14861836, Length=307, Percent_Identity=22.4755700325733, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 43360; Mature: 43360

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAFFHHTMVRGSGIDTVIWELAKRLKKDHDVSIFTFFNEYDNPIVNTISIPFHENRLV
CEEEEEEHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCCCHHH
NAVFAPIIPSSYSFRKKVKDFDVVNVHHFPANFFPFFPTNMDTLNIVTEWSGPPMCLLEN
HHHHHHCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEEC
MNFNERLYMKLARFMNKYAANRADGLLAPCSFVKQWIMDNYGLNSHKMYLDGINFDYFDY
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHH
RNEYNKPDFGGPTILYVGRIAPNKNIDLLIESFEIVKKEFDDSKLVIVGRKTFPAYYRKL
CCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
KKVIKNKNLQEDVIFTGEVPWGELPDYYASCDVYATCSSWEGFLRAEAFAMKKPMVAFDT
HHHHHCCCCCCCEEEECCCCCCCCCCHHHCCCEEEECCCHHHHHHHHHHHHCCCCEEEEC
GANRDTIKDGINGFLVENGDYVSFAEAIIKLIEDPTLNKHMGNEGYRWARKHLDFDVICQ
CCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHCCCHHHHHH
NFSKYLEEEISCR
HHHHHHHHHHCCC
>Mature Secondary Structure
MKIAFFHHTMVRGSGIDTVIWELAKRLKKDHDVSIFTFFNEYDNPIVNTISIPFHENRLV
CEEEEEEHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCCCHHH
NAVFAPIIPSSYSFRKKVKDFDVVNVHHFPANFFPFFPTNMDTLNIVTEWSGPPMCLLEN
HHHHHHCCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEEC
MNFNERLYMKLARFMNKYAANRADGLLAPCSFVKQWIMDNYGLNSHKMYLDGINFDYFDY
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHH
RNEYNKPDFGGPTILYVGRIAPNKNIDLLIESFEIVKKEFDDSKLVIVGRKTFPAYYRKL
CCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
KKVIKNKNLQEDVIFTGEVPWGELPDYYASCDVYATCSSWEGFLRAEAFAMKKPMVAFDT
HHHHHCCCCCCCEEEECCCCCCCCCCHHHCCCEEEECCCHHHHHHHHHHHHCCCCEEEEC
GANRDTIKDGINGFLVENGDYVSFAEAIIKLIEDPTLNKHMGNEGYRWARKHLDFDVICQ
CCCHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHCCCCHHHHHHHCCCHHHHHH
NFSKYLEEEISCR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA