Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15678359

GI number: 15678359

Start: 266738

End: 267403

Strand: Direct

Name: Not Available

Synonym: MTH331

Alternate gene names: 15678359

Gene position: 266738-267403 (Clockwise)

Preceding gene: 15678357

Following gene: 15678360

Centisome position: 15.23

GC content: 47.3

Gene sequence:

>666_bases
GTGACCTTTCTGATTCCAGCATATAATGAGGAAAAATCAATAGGGCCCCTTATTGACAGGATAAAAATGCTTTGTCCTGA
CTCAGAGATCATCGTGGTTGATAATAATTCCTCTGACAGGACCTCTGAGATTGCTACTTCCCGTGGCGTGAGGGTCATCT
TTGAGGGAAAGCAGGGAAAGGCCAATGCCATGGTTGCAGCCTTCAGGAATACCCGTACTGAATACGCGGTTATGATGGAC
GCGGATTTAACATATCTACCCGATGACTCCAGGGTCCTTGTTGAGGTCCTCAAAGCCGAAGGTGCGGATGTCGTCCTTGG
ATCCAGATTAAATGGTGAAAAGGAGGATGGTGCGATATCCCGCATAAACACTGTCGGGAATCATATACTGAGTTTCACAG
CATCCATCCTCTACAGCCCTGTGAGTGATGTGTGCACCGGGCACTGGGCCTTCAATAGGAGAGCAATACGTCACATTCTT
GAGGAGGGTCTCAATTATTCGGGTTTTGAACTTGAGGCTGAGATGTTCTCAAAACTTGCCAGGGCAGGTCTCAAGATAGT
TGAGGTCCCCATAACCTACAGGAAGAGGTCTGATGAACCCAAACTCTCATCATTCACTGATGGCTTCAAGATATTCAGGA
CACTTGTACTTGAGAGGTTGAGGTAG

Upstream 100 bases:

>100_bases
AGGATAAATATTTAAGAGAGGTTCATTTAACTGTTAAAAGTAGAATGTCATGTGTTCAGAGATTTATCATGATTATGTGT
GAGGTGTTCTCATTAAGGAT

Downstream 100 bases:

>100_bases
GGATTAAAATAGCATCATTTATAAAGGTATAAACTACAGGAAAGCACCTAAGATTCAAATTAGCCAATAGATTTCAAGAG
AGCCTCTGAAAAACCTTAAG

Product: mannosyltransferase

Products: UDP; 6-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-; $mannosyl-R

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTFLIPAYNEEKSIGPLIDRIKMLCPDSEIIVVDNNSSDRTSEIATSRGVRVIFEGKQGKANAMVAAFRNTRTEYAVMMD
ADLTYLPDDSRVLVEVLKAEGADVVLGSRLNGEKEDGAISRINTVGNHILSFTASILYSPVSDVCTGHWAFNRRAIRHIL
EEGLNYSGFELEAEMFSKLARAGLKIVEVPITYRKRSDEPKLSSFTDGFKIFRTLVLERLR

Sequences:

>Translated_221_residues
MTFLIPAYNEEKSIGPLIDRIKMLCPDSEIIVVDNNSSDRTSEIATSRGVRVIFEGKQGKANAMVAAFRNTRTEYAVMMD
ADLTYLPDDSRVLVEVLKAEGADVVLGSRLNGEKEDGAISRINTVGNHILSFTASILYSPVSDVCTGHWAFNRRAIRHIL
EEGLNYSGFELEAEMFSKLARAGLKIVEVPITYRKRSDEPKLSSFTDGFKIFRTLVLERLR
>Mature_220_residues
TFLIPAYNEEKSIGPLIDRIKMLCPDSEIIVVDNNSSDRTSEIATSRGVRVIFEGKQGKANAMVAAFRNTRTEYAVMMDA
DLTYLPDDSRVLVEVLKAEGADVVLGSRLNGEKEDGAISRINTVGNHILSFTASILYSPVSDVCTGHWAFNRRAIRHILE
EGLNYSGFELEAEMFSKLARAGLKIVEVPITYRKRSDEPKLSSFTDGFKIFRTLVLERLR

Specific function: Unknown

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Saccharomyces cerevisiae, GI6325441, Length=221, Percent_Identity=28.0542986425339, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.143

Molecular weight: Translated: 24711; Mature: 24579

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLIPAYNEEKSIGPLIDRIKMLCPDSEIIVVDNNSSDRTSEIATSRGVRVIFEGKQGK
CEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCEEEEEECCCCC
ANAMVAAFRNTRTEYAVMMDADLTYLPDDSRVLVEVLKAEGADVVLGSRLNGEKEDGAIS
CHHHHHHHHCCCCEEEEEEECCEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHH
RINTVGNHILSFTASILYSPVSDVCTGHWAFNRRAIRHILEEGLNYSGFELEAEMFSKLA
HHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHH
RAGLKIVEVPITYRKRSDEPKLSSFTDGFKIFRTLVLERLR
HCCCEEEEECEEECCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TFLIPAYNEEKSIGPLIDRIKMLCPDSEIIVVDNNSSDRTSEIATSRGVRVIFEGKQGK
EEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHCCCEEEEEECCCCC
ANAMVAAFRNTRTEYAVMMDADLTYLPDDSRVLVEVLKAEGADVVLGSRLNGEKEDGAIS
CHHHHHHHHCCCCEEEEEEECCEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHH
RINTVGNHILSFTASILYSPVSDVCTGHWAFNRRAIRHILEEGLNYSGFELEAEMFSKLA
HHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHH
RAGLKIVEVPITYRKRSDEPKLSSFTDGFKIFRTLVLERLR
HCCCEEEEECEEECCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-acetyl-D-glucosamine; 6-(alpha-D-mannosyl)-beta-D-mannosyl-R

Specific reaction: UDP-N-acetyl-D-glucosamine + 6-(alpha-D-mannosyl)-beta-D-mannosyl-R = UDP + 6-(2-[N-acetyl-beta- $D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]