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Identifier: 15678341

GI number: 15678341

Start: 248269

End: 248709

Strand: Direct

Name: Not Available

Synonym: MTH313

Alternate gene names: 15678341

Gene position: 248269-248709 (Clockwise)

Preceding gene: 15678340

Following gene: 15678342

Centisome position: 14.18

GC content: 56.92

Gene sequence:

>441_bases
ATGGACAGGGACATACCACTCAAGGGACTCCTCTCAATAATCCTCAGGAGTCACAGGGTCTTCATCGGGAGGGAGCTGGG
ACACCTGAACCTCACAGACGCCCAGGTGGCATGCCTCCTGAGGATCCACAGGGAACCAGGGATAAAACAGGATGAACTCG
CCACCTTCTTCCACGTGGACAAGGGAACCATAGCAAGGACCCTGAGGCGCCTGGAGGAGAGCGGATTCATTGAGAGAGAG
CAGGACCCGGAGAACAGGCGCAGGTACATCCTGGAGGTAACCAGGAGGGGCGAGGAAATCATCCCCCTCATACTGAAGGT
TGAGGAGCGCTGGGAGGACCTCCTCTTCAGAGACTTCACAGAGGATGAGAGGAAACTCTTCAGGAAGATGTGCCGGAGAC
TGGCAGAGGAGGCAGTCAGGATGAGGGGTGAGTGGAGGTGA

Upstream 100 bases:

>100_bases
GTCCATGACTTCAAACTCTAGTCTTTTTTCTGGACTATGTTGCAGATGCAACAGTTGCAATGACAACATTTATATATGTT
TTCCCACCAGATAGATCAGC

Downstream 100 bases:

>100_bases
GCGAGGGAATCGAAATCATAAGGGGAGACCCCAGGAGGGCCCTCATCAAACTATCAGGGCCACTCATAGTTGCAATGCTC
CTCACATCCATCTACAACCT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MDRDIPLKGLLSIILRSHRVFIGRELGHLNLTDAQVACLLRIHREPGIKQDELATFFHVDKGTIARTLRRLEESGFIERE
QDPENRRRYILEVTRRGEEIIPLILKVEERWEDLLFRDFTEDERKLFRKMCRRLAEEAVRMRGEWR

Sequences:

>Translated_146_residues
MDRDIPLKGLLSIILRSHRVFIGRELGHLNLTDAQVACLLRIHREPGIKQDELATFFHVDKGTIARTLRRLEESGFIERE
QDPENRRRYILEVTRRGEEIIPLILKVEERWEDLLFRDFTEDERKLFRKMCRRLAEEAVRMRGEWR
>Mature_146_residues
MDRDIPLKGLLSIILRSHRVFIGRELGHLNLTDAQVACLLRIHREPGIKQDELATFFHVDKGTIARTLRRLEESGFIERE
QDPENRRRYILEVTRRGEEIIPLILKVEERWEDLLFRDFTEDERKLFRKMCRRLAEEAVRMRGEWR

Specific function: Transcription Factor That Activates Expression Of Genes Such As Molecular Chaperones (Grol, Gros, Dnak, Grpe, And Cbpa), Proteins Involved In Acid Resistance (Hdea, Hdeb, And Gada), The Starvation Lipoprotein Slp, Virulence Protein Hlye/Clya. Represses Ex

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 17594; Mature: 17594

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRDIPLKGLLSIILRSHRVFIGRELGHLNLTDAQVACLLRIHREPGIKQDELATFFHVD
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCC
KGTIARTLRRLEESGFIEREQDPENRRRYILEVTRRGEEIIPLILKVEERWEDLLFRDFT
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
EDERKLFRKMCRRLAEEAVRMRGEWR
HHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDRDIPLKGLLSIILRSHRVFIGRELGHLNLTDAQVACLLRIHREPGIKQDELATFFHVD
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCC
KGTIARTLRRLEESGFIEREQDPENRRRYILEVTRRGEEIIPLILKVEERWEDLLFRDFT
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
EDERKLFRKMCRRLAEEAVRMRGEWR
HHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]