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Identifier: 15678274

GI number: 15678274

Start: 189721

End: 191553

Strand: Direct

Name: Not Available

Synonym: MTH246

Alternate gene names: NA

Gene position: 189721-191553 (Clockwise)

Preceding gene: 15678273

Following gene: 15678275

Centisome position: 10.83

GC content: 53.79

Gene sequence:

>1833_bases
ATGAAGATTGTTCCAGATACAAGTGTTATTGTTGACGGCAGGATCACCGGGATAGTCCAGGAGGACGAGTTCAGGGGCAG
CGAGGTGATCGTGCCCGAGGCAGTTGTATCTGAACTCGAATACCAGGCCAACCGTGGAAGGGAGACAGGTTTCAATGGCC
TCGAGGAACTGAAGAACCTCCAGAAGCTCCACAAGGAGAATATAATATCCATGATATTCGTCGGGCGCCGCCCCACAGTG
GATGAGATATCCCTCTCAAGGGGTGGTGAGATAGATGCCATGATAAGGTCCACGGCAAGGGAATATGATGCCCTCCTTAT
AACAAGTGACCGGGTCCAGGCCGAGGTCGGGAAGGCCCAGGGCCTCGATGTCTTCTACATCAAACCAGAGGTCCTGGAGT
ACGAGGAGCTGGAGATAAGCAAGTACTTCGATGAGAACACCATGTCGGTCCACCTCAAGGAGAATGTCGTTCCGATGGCC
AAGAAGGGCCGGCCAGGGGAAATCCAGCTGGTTGAGATAGGTAAAAGACCGCTTAAACATTCAGATATAAGCAGGATGGC
CCGTGAGATCGTGGAGAGGGCCAAGAGTGACTTCAAGAGCTTTATAGAGATCGAAATGGAGGGCGCCACGGTCGTACAGT
TCCGGGAGTACAGGATATCCATTGCAAGACCACCATTCTCAGAGGCCTTTGAGATAACCGCGGTCAGGCCGGTGGCGAGG
GTTTCACTGGAGGACTACAGGCTCTCAGACAGGCTCGTGGAGAGGCTGAGGGATACTGCCAAGGGGGTGCTCATTGCAGG
TTCCCCCGGGGCAGGTAAGAGTACCTTTGCCCAGGCAGTGGCAGAGTTCTACAGCAGGGATATGAAGGCGGTTGTCAAGA
CCATGGAGTCACCCAGGGACCTCCAGGTTGGTGATGAGATAACACAGTATGCACCCATTGAGAGGGACATGCAGAAGACG
GCAGACATACTCCTCCTCGTGAGGCCCGACTACACCATCTACGATGAACTCAGAAAGACCCGTGACTTCAGGATATTTGC
GGATATGAGGCTCGCGGGTGTGGGTATGGTTGGTGTGGTCCACGCCACAAGGCCCATAGACGCCATACAGAGGATCCTTG
GAAGGGTTGAGCTCGGCGTCATACCCTCAGTTGTTGATACAACAATATTCATCGAGGATGGGGAGGTTAAGGCTGTCTAC
GATGTCTCCCTCACCGTGAAGGTGCCCACGGGCATGCAGGAGGCTGACCTTGCAAGGCCGGTCATCGAGATCAGGGACCT
TGAATCAGGGGAACTCATGCATGAGATATACACCTACGGTGAGCAGACAATAGTCATGGACGTCTCAAAGGCAGCCCCTT
CAGGGCGCAAACCGTCAGCCCACAGGATAGCTGAGAGGGAGATCGAGAGGGAGTTCCGCAGGAGGATCCCGGGTGCCCGG
GTCAGGGTTGAACTTGAATCTGATGAACGTGCCAGGGTCTGGATAGATGAGAAGTACATACCCCAGGTTATAGGTAAGAA
GGGTAAGACCATTGAGGAGATCGAGAACAGCATAGGCATAAGCATAGGTGTGGAGCCCCTGGAGGAGAGGGAAATCGAGG
AGACCCTTGAGGTCCCCGTTGAACTTGCAGGGAATTATGTGGTTCTAAACTTTGGCAAGGACGCTGTGGGGGTGTCCTTT
GACATACTTGTGGATGATGAGTACCTCTTCACAGCCACTGTAGGAAAGAAGGGGACCATAAAGCTCAGAAGGGACATAGA
GCTGGCTGACATCATAATGGAGGCCGTGAAGAACAGCATACCTGTGAGGGCCAGGGTCAGGCCAGAGCGTTGA

Upstream 100 bases:

>100_bases
CAGGTCCTGCTTCTACCGGAGTATTGATGGAGATGAACTCAAAGTCAGGGAGGACGCCGTGAAGGTCTTTGACCCTGAAG
AGATATATGGAGATGGTTAG

Downstream 100 bases:

>100_bases
GGGTGGTGTGATGAGGATAGGTGTCTCAACCCTTGCACTCACACCGTCCCCACTGGGGGAGATGCTGGAGTACATCGAGG
CCCTTGGGGCCGAGTGCTGT

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MKIVPDTSVIVDGRITGIVQEDEFRGSEVIVPEAVVSELEYQANRGRETGFNGLEELKNLQKLHKENIISMIFVGRRPTV
DEISLSRGGEIDAMIRSTAREYDALLITSDRVQAEVGKAQGLDVFYIKPEVLEYEELEISKYFDENTMSVHLKENVVPMA
KKGRPGEIQLVEIGKRPLKHSDISRMAREIVERAKSDFKSFIEIEMEGATVVQFREYRISIARPPFSEAFEITAVRPVAR
VSLEDYRLSDRLVERLRDTAKGVLIAGSPGAGKSTFAQAVAEFYSRDMKAVVKTMESPRDLQVGDEITQYAPIERDMQKT
ADILLLVRPDYTIYDELRKTRDFRIFADMRLAGVGMVGVVHATRPIDAIQRILGRVELGVIPSVVDTTIFIEDGEVKAVY
DVSLTVKVPTGMQEADLARPVIEIRDLESGELMHEIYTYGEQTIVMDVSKAAPSGRKPSAHRIAEREIEREFRRRIPGAR
VRVELESDERARVWIDEKYIPQVIGKKGKTIEEIENSIGISIGVEPLEEREIEETLEVPVELAGNYVVLNFGKDAVGVSF
DILVDDEYLFTATVGKKGTIKLRRDIELADIIMEAVKNSIPVRARVRPER

Sequences:

>Translated_610_residues
MKIVPDTSVIVDGRITGIVQEDEFRGSEVIVPEAVVSELEYQANRGRETGFNGLEELKNLQKLHKENIISMIFVGRRPTV
DEISLSRGGEIDAMIRSTAREYDALLITSDRVQAEVGKAQGLDVFYIKPEVLEYEELEISKYFDENTMSVHLKENVVPMA
KKGRPGEIQLVEIGKRPLKHSDISRMAREIVERAKSDFKSFIEIEMEGATVVQFREYRISIARPPFSEAFEITAVRPVAR
VSLEDYRLSDRLVERLRDTAKGVLIAGSPGAGKSTFAQAVAEFYSRDMKAVVKTMESPRDLQVGDEITQYAPIERDMQKT
ADILLLVRPDYTIYDELRKTRDFRIFADMRLAGVGMVGVVHATRPIDAIQRILGRVELGVIPSVVDTTIFIEDGEVKAVY
DVSLTVKVPTGMQEADLARPVIEIRDLESGELMHEIYTYGEQTIVMDVSKAAPSGRKPSAHRIAEREIEREFRRRIPGAR
VRVELESDERARVWIDEKYIPQVIGKKGKTIEEIENSIGISIGVEPLEEREIEETLEVPVELAGNYVVLNFGKDAVGVSF
DILVDDEYLFTATVGKKGTIKLRRDIELADIIMEAVKNSIPVRARVRPER
>Mature_610_residues
MKIVPDTSVIVDGRITGIVQEDEFRGSEVIVPEAVVSELEYQANRGRETGFNGLEELKNLQKLHKENIISMIFVGRRPTV
DEISLSRGGEIDAMIRSTAREYDALLITSDRVQAEVGKAQGLDVFYIKPEVLEYEELEISKYFDENTMSVHLKENVVPMA
KKGRPGEIQLVEIGKRPLKHSDISRMAREIVERAKSDFKSFIEIEMEGATVVQFREYRISIARPPFSEAFEITAVRPVAR
VSLEDYRLSDRLVERLRDTAKGVLIAGSPGAGKSTFAQAVAEFYSRDMKAVVKTMESPRDLQVGDEITQYAPIERDMQKT
ADILLLVRPDYTIYDELRKTRDFRIFADMRLAGVGMVGVVHATRPIDAIQRILGRVELGVIPSVVDTTIFIEDGEVKAVY
DVSLTVKVPTGMQEADLARPVIEIRDLESGELMHEIYTYGEQTIVMDVSKAAPSGRKPSAHRIAEREIEREFRRRIPGAR
VRVELESDERARVWIDEKYIPQVIGKKGKTIEEIENSIGISIGVEPLEEREIEETLEVPVELAGNYVVLNFGKDAVGVSF
DILVDDEYLFTATVGKKGTIKLRRDIELADIIMEAVKNSIPVRARVRPER

Specific function: Unknown

COG id: COG1855

COG function: function code R; ATPase (PilT family)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004087
- InterPro:   IPR009019
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR002716
- InterPro:   IPR006596
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E; PF00013 KH_1; PF01850 PIN [H]

EC number: NA

Molecular weight: Translated: 68782; Mature: 68782

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVPDTSVIVDGRITGIVQEDEFRGSEVIVPEAVVSELEYQANRGRETGFNGLEELKNL
CCCCCCCCEEECCEEEEEEECCCCCCCEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
QKLHKENIISMIFVGRRPTVDEISLSRGGEIDAMIRSTAREYDALLITSDRVQAEVGKAQ
HHHHHHCCEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHCEEEEECCHHHHHHCCCC
GLDVFYIKPEVLEYEELEISKYFDENTMSVHLKENVVPMAKKGRPGEIQLVEIGKRPLKH
CCEEEEECCCHHCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCC
SDISRMAREIVERAKSDFKSFIEIEMEGATVVQFREYRISIARPPFSEAFEITAVRPVAR
HHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEEEEEECCCCCCCCEEEEEECHHHH
VSLEDYRLSDRLVERLRDTAKGVLIAGSPGAGKSTFAQAVAEFYSRDMKAVVKTMESPRD
CCHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LQVGDEITQYAPIERDMQKTADILLLVRPDYTIYDELRKTRDFRIFADMRLAGVGMVGVV
CCCCCHHHHCCCCHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEEECEECCCCEEEEE
HATRPIDAIQRILGRVELGVIPSVVDTTIFIEDGEVKAVYDVSLTVKVPTGMQEADLARP
ECCCCHHHHHHHHHHHHHCCCCHHHCEEEEEECCCEEEEEEEEEEEECCCCCCHHHHHCC
VIEIRDLESGELMHEIYTYGEQTIVMDVSKAAPSGRKPSAHRIAEREIEREFRRRIPGAR
HHHEECCCCCHHHHHHHHCCCCEEEEEEHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCE
VRVELESDERARVWIDEKYIPQVIGKKGKTIEEIENSIGISIGVEPLEEREIEETLEVPV
EEEEECCCCCEEEEECHHHHHHHHCCCCCCHHHHHHHCCEEECCCCHHHHHHHHHHHCCH
ELAGNYVVLNFGKDAVGVSFDILVDDEYLFTATVGKKGTIKLRRDIELADIIMEAVKNSI
HHCCCEEEEEECCCCCCEEEEEEECCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCC
PVRARVRPER
CEEEECCCCC
>Mature Secondary Structure
MKIVPDTSVIVDGRITGIVQEDEFRGSEVIVPEAVVSELEYQANRGRETGFNGLEELKNL
CCCCCCCCEEECCEEEEEEECCCCCCCEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
QKLHKENIISMIFVGRRPTVDEISLSRGGEIDAMIRSTAREYDALLITSDRVQAEVGKAQ
HHHHHHCCEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHCEEEEECCHHHHHHCCCC
GLDVFYIKPEVLEYEELEISKYFDENTMSVHLKENVVPMAKKGRPGEIQLVEIGKRPLKH
CCEEEEECCCHHCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCC
SDISRMAREIVERAKSDFKSFIEIEMEGATVVQFREYRISIARPPFSEAFEITAVRPVAR
HHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEEEEEECCCCCCCCEEEEEECHHHH
VSLEDYRLSDRLVERLRDTAKGVLIAGSPGAGKSTFAQAVAEFYSRDMKAVVKTMESPRD
CCHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LQVGDEITQYAPIERDMQKTADILLLVRPDYTIYDELRKTRDFRIFADMRLAGVGMVGVV
CCCCCHHHHCCCCHHHHHCCCCEEEEECCCCHHHHHHHHCCCEEEEEECEECCCCEEEEE
HATRPIDAIQRILGRVELGVIPSVVDTTIFIEDGEVKAVYDVSLTVKVPTGMQEADLARP
ECCCCHHHHHHHHHHHHHCCCCHHHCEEEEEECCCEEEEEEEEEEEECCCCCCHHHHHCC
VIEIRDLESGELMHEIYTYGEQTIVMDVSKAAPSGRKPSAHRIAEREIEREFRRRIPGAR
HHHEECCCCCHHHHHHHHCCCCEEEEEEHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCE
VRVELESDERARVWIDEKYIPQVIGKKGKTIEEIENSIGISIGVEPLEEREIEETLEVPV
EEEEECCCCCEEEEECHHHHHHHHCCCCCCHHHHHHHCCEEECCCCHHHHHHHHHHHCCH
ELAGNYVVLNFGKDAVGVSFDILVDDEYLFTATVGKKGTIKLRRDIELADIIMEAVKNSI
HHCCCEEEEEECCCCCCEEEEEEECCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCC
PVRARVRPER
CEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]