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Identifier: 15678237

GI number: 15678237

Start: 150345

End: 151025

Strand: Direct

Name: Not Available

Synonym: MTH209

Alternate gene names: 15678237

Gene position: 150345-151025 (Clockwise)

Preceding gene: 15678236

Following gene: 15678238

Centisome position: 8.58

GC content: 47.58

Gene sequence:

>681_bases
ATGCTGAAGGCGGTTTTCTTTGATATTGATGATACTCTCTATGACACCTCAGGATTTGCTAAACTTGCAAGAAAGGCTGC
TCTGAACGTCATGATAGACGCAGGTCTCCCATTAACACAGGAGGAGGCCTACAAGCTTCTCAGGGAGATAATATCCGAGA
AAGGATCAAACTATGACAGGCATTTCAATGTCCTGACAAAGACGGTTTTCGGTGAGGAGAAACCACTGCTCATTGCCCTT
GGAATGATAACATACCACAACGTCAAGTTCGCCCTCCTGAGACCATTCCCCAACACCACATCCACACTCATTGACCTCAA
GAGTAAGGGGTACAGGCTTGGGGTCATCTCAAACGGCATAACGATAAAGCAGTGGGAGAAGCTCATAAGACTCGGCATCC
ACCACTTCTTCGATGAGGTCGTCACCTCAGACGAGGTCGGCTTCGAAAAACCCAACATAAGGATCTTTGAGGAGGCCCTC
AGGAGGATGGGCTGCAAACCCGAAAGATCAGTGATGGTTGGTAACAAGTTCAATGAGGACATACTGGGAGCCACAAATGC
GGGTATGTCAGCCATACTGGTCAACTCAGAGTTAACGGAGGCAGAAAGGGATCACGTTGAGAAGAACGGTCTTGATGTTA
CGGTCATAGATGATATCAGTCAGCTTAAGGAGATCCTTTAG

Upstream 100 bases:

>100_bases
TTTAAGACACCATCTCCATGATTTCCGCATCCCACAGTTAAACCAACAATGTTATAATTGATTAGTTATAGAGTTTCATT
ACAGAGAAATAGGTGGGACG

Downstream 100 bases:

>100_bases
TTTTCATGTAAGGAGGGATTTCAGCGGGCCTTCCCCGTTCCCATGAAATCTCTCATCCACGGGGGATGAACATGATGGAC
ATCGATAAGGGGGATGAATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MLKAVFFDIDDTLYDTSGFAKLARKAALNVMIDAGLPLTQEEAYKLLREIISEKGSNYDRHFNVLTKTVFGEEKPLLIAL
GMITYHNVKFALLRPFPNTTSTLIDLKSKGYRLGVISNGITIKQWEKLIRLGIHHFFDEVVTSDEVGFEKPNIRIFEEAL
RRMGCKPERSVMVGNKFNEDILGATNAGMSAILVNSELTEAERDHVEKNGLDVTVIDDISQLKEIL

Sequences:

>Translated_226_residues
MLKAVFFDIDDTLYDTSGFAKLARKAALNVMIDAGLPLTQEEAYKLLREIISEKGSNYDRHFNVLTKTVFGEEKPLLIAL
GMITYHNVKFALLRPFPNTTSTLIDLKSKGYRLGVISNGITIKQWEKLIRLGIHHFFDEVVTSDEVGFEKPNIRIFEEAL
RRMGCKPERSVMVGNKFNEDILGATNAGMSAILVNSELTEAERDHVEKNGLDVTVIDDISQLKEIL
>Mature_226_residues
MLKAVFFDIDDTLYDTSGFAKLARKAALNVMIDAGLPLTQEEAYKLLREIISEKGSNYDRHFNVLTKTVFGEEKPLLIAL
GMITYHNVKFALLRPFPNTTSTLIDLKSKGYRLGVISNGITIKQWEKLIRLGIHHFFDEVVTSDEVGFEKPNIRIFEEAL
RRMGCKPERSVMVGNKFNEDILGATNAGMSAILVNSELTEAERDHVEKNGLDVTVIDDISQLKEIL

Specific function: Unknown

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily

Homologues:

Organism=Escherichia coli, GI1790833, Length=204, Percent_Identity=28.921568627451, Blast_Score=78, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28571108, Length=190, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45552117, Length=81, Percent_Identity=38.2716049382716, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y209_METTH (O26311)

Other databases:

- EMBL:   AE000666
- PIR:   F69125
- RefSeq:   NP_275352.1
- ProteinModelPortal:   O26311
- SMR:   O26311
- STRING:   O26311
- GeneID:   1470170
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH209
- NMPDR:   fig|187420.1.peg.207
- eggNOG:   arNOG05958
- HOGENOM:   HBG742904
- OMA:   ELEYCID
- PhylomeDB:   O26311
- ProtClustDB:   CLSK865257
- BioCyc:   MTHE187420:MTH209-MONOMER
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR011950
- InterPro:   IPR006439
- InterPro:   IPR005833
- Gene3D:   G3DSA:3.40.50.1000
- PRINTS:   PR00413
- TIGRFAMs:   TIGR02253
- TIGRFAMs:   TIGR01549

Pfam domain/function: PF00702 Hydrolase; SSF56784 SSF56784

EC number: NA

Molecular weight: Translated: 25464; Mature: 25464

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAVFFDIDDTLYDTSGFAKLARKAALNVMIDAGLPLTQEEAYKLLREIISEKGSNYDR
CCEEEEECCCCHHHCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCHH
HFNVLTKTVFGEEKPLLIALGMITYHNVKFALLRPFPNTTSTLIDLKSKGYRLGVISNGI
HHHHHHHHHCCCCCCEEEEEEHHHHCCEEEEEEECCCCCHHHHEECCCCCEEEEEEECCC
TIKQWEKLIRLGIHHFFDEVVTSDEVGFEKPNIRIFEEALRRMGCKPERSVMVGNKFNED
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCH
ILGATNAGMSAILVNSELTEAERDHVEKNGLDVTVIDDISQLKEIL
HCCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHC
>Mature Secondary Structure
MLKAVFFDIDDTLYDTSGFAKLARKAALNVMIDAGLPLTQEEAYKLLREIISEKGSNYDR
CCEEEEECCCCHHHCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHCCCCCHH
HFNVLTKTVFGEEKPLLIALGMITYHNVKFALLRPFPNTTSTLIDLKSKGYRLGVISNGI
HHHHHHHHHCCCCCCEEEEEEHHHHCCEEEEEEECCCCCHHHHEECCCCCEEEEEEECCC
TIKQWEKLIRLGIHHFFDEVVTSDEVGFEKPNIRIFEEALRRMGCKPERSVMVGNKFNED
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCH
ILGATNAGMSAILVNSELTEAERDHVEKNGLDVTVIDDISQLKEIL
HCCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463