| Definition | Methanothermobacter thermautotrophicus str. Delta H chromosome, complete genome. |
|---|---|
| Accession | NC_000916 |
| Length | 1,751,377 |
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Identifier: 15678202
GI number: 15678202
Start: 118633
End: 120990
Strand: Direct
Name: Not Available
Synonym: MTH174
Alternate gene names: 15678202
Gene position: 118633-120990 (Clockwise)
Preceding gene: 15678199
Following gene: 15678203
Centisome position: 6.77
GC content: 53.6
Gene sequence:
>2358_bases ATGAATCCAATGGCCATCATATCCATCACAGCCTTCGTGGTGGCCCTTGTATCGGGTGTGTACATATTCGTCAAGAACCC TGAAAGCCGCTTTAACAGGGCACTCCTCCTTTTCTCAGCACTGATAGCCTACCTTTCACTCACAGATTTCGGCCTTTACA TTTCAGAGTCCTACATGATGGCCGACTTCTGGGTAAGGATGGGATTCCTCTGGCCCATTGTGGTCCCGGTCATACTGCAC ATGGTCCTGCTCTTCACGGGTAGAAGACCAACCATGCCACTCCTTGCAGTTATCTACGCACCTGCAGTGGTCATAGCGGC CCTTGAACTAACAACGGATCTTATAACCGCGGGGCCCACCATGACTTCATGGGGCTGGACCTTCAGTGCCGCGGAGAATT CGCTTCCCTACCAGATCTCAAATATCTGGGGATTCATCATAGCATCAGTCGCCATCATACTTGTGGCCCTGCACTGGAGG TCATCCCGGGGTTCAGATCGGACGCAGGCCCACTACCTCCTCACAGGCCTCATCTTACCTGTCCTGGCGGGCGTCCTGAC GGATCTCGTCCTCCCGGCAGCTGGCATGGCTGTACCTTCACTCACAGATCCTTCAGCCGCACTCGGGGTTTCCATCATAG CCTATGGTGTTATGAGGTTCCGTTTACCAATCCTGAGCCCCTTAAACGCTGCCATGGATATTGTGAGGAACATGAACACC TTCCTTATAATCACAGATCTTGGGCTGAATATACACTACGTCAACCCAGCAACTGAGAGGCTAACCGGTCGTCGGGCAGC GGAATTCTCAGGCAGGAAGGTGACTGAGGTCCTTAAATTCGATGAACTCAGCACCGGCTCCATCATGGAGTCCCGGCTCA GAGGTAAGGATGAATGGATCCCGGTCATCGTATCGGCGGGTCATGTGCATGGCTCAGGGGGTGAACATCTGGGCCTGCTC TTCACGGGTTCAGATATGCGGCCCATCCTGGAGATGGAGGAAAAGCTGAGGAGGAGGGAGGATCGTCTTGTGCTCCTGAC AGAACACATGGCTGATGGTCTTGGAGAATTTGACAGGGACTTCAACTTCAGATACCTCAGCCCATCGGTGAAGAAGATAA CAGGCTACGATCATGAAATGCTCACCGGCATGTCAGCCCTTGACTTCATGGACTACCTGCACCCCGATGACACGGAGGAG GTTAAGAAACTCATACTGACCCGGGGGGAAGGCCACAGGGCAACCTTCAGGATAAGAAGGCCCGATGGGAACTACAGGTG GGTGGAATACGTTGACAGACCAATCAGGACTGATGGTGATATCGAGGGCTACGTGTTCGGTTTGAGGGATATACATGAAC ATAAACTGGCAGAGGAGGCCCTGATCGTCAGCAAGGAGAAATTCAGGGAACTCTTCAGGAACATGAGGAGCGGCATAATT GCTGTTGAATCTGATGGAAAGGGATTCCGGGTTAAATCCATGAACCCGGCAGCCGAGAGGATGGAGGGCGTCTCCTGCGC CGCCATCCAGGGTATGGATCTTCAGGAGGCACTCCCTGAGATCTGGAACTCCCCCATCAGGAGGGCCCTCCAGGAGATCA GGGAGACCGGTGAGGCCATCCATTGTCCGGAGGTTGAATGTGGGGAGGGATGGTTTGATGTGCACCTCCACCAGCTATCA ACCGGGGAGGTGGTCATCATCTGCACCGACATAACCCTCAGGAAGCAGTATGAGGATGAACTCAGAGCATCGCTCAGGGA GAAGGAGGCCCTCCTCAGGGAGGTGCACCACAGGGTCAAGAACAACTTCCAGGTAATATCCAGTCTCATAAATCTTCAGC TCGATGATGCTGAGGATCCAGCGCCCCTCAGGGACCTTCAGAGCAGGATCCAGTCCATGGCCCTCGTCCATGAACTGCTC TATGAGTCAGAGGATCTCACAAGCATTGACATGGGGCGCTACATAGAGAGGCTCACCTCCTCCATAGTTAACAGCCACCA TAACGGGGAAATAGAAGTTGAGGTGGCGGTGGGTGACATAACACTTCCCCTTGAAACAGCCATCCCCCTGGGTCTCATCA TCAACGAACTCGTCACCAACTCCTTCAAGCATGCCTTCACGTCCGGTGGAATGATAAGCGTAGAACTGGAGGAACATGGC GGTGAATTCACACTCACCATCACAGATAATGGTGTGGGTCTTCCCCCTGATTTTATAATTGAAGATTCGGATTCCCTGGG CCTCAGGCTGGTGGCGGGCCTTGTGGATCAGATTGACGGGACCCTCGAGGTTTCCGGGGAGGATGGGACCAGGTTCAGGT TAACCTTTGGAGTTGTTCCTTACCGTCGGAGGGTCTGA
Upstream 100 bases:
>100_bases TGATATAATTAATAACATAGTGGGGCAGACATGCTGCGTCAGGTTCCTCCACAGAGGGGCATGATGTAAATCGGGGGGTG ATGTAGGTGGGGGTTTTCCC
Downstream 100 bases:
>100_bases TGATCTGTGATTTGAGGGTATTCCTGTGGGTCTTGGAGGGTCTGAAAATCATAACTTGATGAGCAGGCACCGACTCTGAT TCAGGGGTAATGGCAAAATT
Product: sensory transduction histidine kinase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 785; Mature: 785
Protein sequence:
>785_residues MNPMAIISITAFVVALVSGVYIFVKNPESRFNRALLLFSALIAYLSLTDFGLYISESYMMADFWVRMGFLWPIVVPVILH MVLLFTGRRPTMPLLAVIYAPAVVIAALELTTDLITAGPTMTSWGWTFSAAENSLPYQISNIWGFIIASVAIILVALHWR SSRGSDRTQAHYLLTGLILPVLAGVLTDLVLPAAGMAVPSLTDPSAALGVSIIAYGVMRFRLPILSPLNAAMDIVRNMNT FLIITDLGLNIHYVNPATERLTGRRAAEFSGRKVTEVLKFDELSTGSIMESRLRGKDEWIPVIVSAGHVHGSGGEHLGLL FTGSDMRPILEMEEKLRRREDRLVLLTEHMADGLGEFDRDFNFRYLSPSVKKITGYDHEMLTGMSALDFMDYLHPDDTEE VKKLILTRGEGHRATFRIRRPDGNYRWVEYVDRPIRTDGDIEGYVFGLRDIHEHKLAEEALIVSKEKFRELFRNMRSGII AVESDGKGFRVKSMNPAAERMEGVSCAAIQGMDLQEALPEIWNSPIRRALQEIRETGEAIHCPEVECGEGWFDVHLHQLS TGEVVIICTDITLRKQYEDELRASLREKEALLREVHHRVKNNFQVISSLINLQLDDAEDPAPLRDLQSRIQSMALVHELL YESEDLTSIDMGRYIERLTSSIVNSHHNGEIEVEVAVGDITLPLETAIPLGLIINELVTNSFKHAFTSGGMISVELEEHG GEFTLTITDNGVGLPPDFIIEDSDSLGLRLVAGLVDQIDGTLEVSGEDGTRFRLTFGVVPYRRRV
Sequences:
>Translated_785_residues MNPMAIISITAFVVALVSGVYIFVKNPESRFNRALLLFSALIAYLSLTDFGLYISESYMMADFWVRMGFLWPIVVPVILH MVLLFTGRRPTMPLLAVIYAPAVVIAALELTTDLITAGPTMTSWGWTFSAAENSLPYQISNIWGFIIASVAIILVALHWR SSRGSDRTQAHYLLTGLILPVLAGVLTDLVLPAAGMAVPSLTDPSAALGVSIIAYGVMRFRLPILSPLNAAMDIVRNMNT FLIITDLGLNIHYVNPATERLTGRRAAEFSGRKVTEVLKFDELSTGSIMESRLRGKDEWIPVIVSAGHVHGSGGEHLGLL FTGSDMRPILEMEEKLRRREDRLVLLTEHMADGLGEFDRDFNFRYLSPSVKKITGYDHEMLTGMSALDFMDYLHPDDTEE VKKLILTRGEGHRATFRIRRPDGNYRWVEYVDRPIRTDGDIEGYVFGLRDIHEHKLAEEALIVSKEKFRELFRNMRSGII AVESDGKGFRVKSMNPAAERMEGVSCAAIQGMDLQEALPEIWNSPIRRALQEIRETGEAIHCPEVECGEGWFDVHLHQLS TGEVVIICTDITLRKQYEDELRASLREKEALLREVHHRVKNNFQVISSLINLQLDDAEDPAPLRDLQSRIQSMALVHELL YESEDLTSIDMGRYIERLTSSIVNSHHNGEIEVEVAVGDITLPLETAIPLGLIINELVTNSFKHAFTSGGMISVELEEHG GEFTLTITDNGVGLPPDFIIEDSDSLGLRLVAGLVDQIDGTLEVSGEDGTRFRLTFGVVPYRRRV >Mature_785_residues MNPMAIISITAFVVALVSGVYIFVKNPESRFNRALLLFSALIAYLSLTDFGLYISESYMMADFWVRMGFLWPIVVPVILH MVLLFTGRRPTMPLLAVIYAPAVVIAALELTTDLITAGPTMTSWGWTFSAAENSLPYQISNIWGFIIASVAIILVALHWR SSRGSDRTQAHYLLTGLILPVLAGVLTDLVLPAAGMAVPSLTDPSAALGVSIIAYGVMRFRLPILSPLNAAMDIVRNMNT FLIITDLGLNIHYVNPATERLTGRRAAEFSGRKVTEVLKFDELSTGSIMESRLRGKDEWIPVIVSAGHVHGSGGEHLGLL FTGSDMRPILEMEEKLRRREDRLVLLTEHMADGLGEFDRDFNFRYLSPSVKKITGYDHEMLTGMSALDFMDYLHPDDTEE VKKLILTRGEGHRATFRIRRPDGNYRWVEYVDRPIRTDGDIEGYVFGLRDIHEHKLAEEALIVSKEKFRELFRNMRSGII AVESDGKGFRVKSMNPAAERMEGVSCAAIQGMDLQEALPEIWNSPIRRALQEIRETGEAIHCPEVECGEGWFDVHLHQLS TGEVVIICTDITLRKQYEDELRASLREKEALLREVHHRVKNNFQVISSLINLQLDDAEDPAPLRDLQSRIQSMALVHELL YESEDLTSIDMGRYIERLTSSIVNSHHNGEIEVEVAVGDITLPLETAIPLGLIINELVTNSFKHAFTSGGMISVELEEHG GEFTLTITDNGVGLPPDFIIEDSDSLGLRLVAGLVDQIDGTLEVSGEDGTRFRLTFGVVPYRRRV
Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]
COG id: COG2202
COG function: function code T; FOG: PAS/PAC domain
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 histidine kinase domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR022066 - InterPro: IPR011495 - InterPro: IPR005467 [H]
Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 87728; Mature: 87728
Theoretical pI: Translated: 5.02; Mature: 5.02
Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNPMAIISITAFVVALVSGVYIFVKNPESRFNRALLLFSALIAYLSLTDFGLYISESYMM CCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH ADFWVRMGFLWPIVVPVILHMVLLFTGRRPTMPLLAVIYAPAVVIAALELTTDLITAGPT HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC MTSWGWTFSAAENSLPYQISNIWGFIIASVAIILVALHWRSSRGSDRTQAHYLLTGLILP CCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH VLAGVLTDLVLPAAGMAVPSLTDPSAALGVSIIAYGVMRFRLPILSPLNAAMDIVRNMNT HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCE FLIITDLGLNIHYVNPATERLTGRRAAEFSGRKVTEVLKFDELSTGSIMESRLRGKDEWI EEEEEECCCEEEEECCHHHHHCCCHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCE PVIVSAGHVHGSGGEHLGLLFTGSDMRPILEMEEKLRRREDRLVLLTEHMADGLGEFDRD EEEEEECEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEHHHHHCCHHHHCCC FNFRYLSPSVKKITGYDHEMLTGMSALDFMDYLHPDDTEEVKKLILTRGEGHRATFRIRR CCEEEECCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEEC PDGNYRWVEYVDRPIRTDGDIEGYVFGLRDIHEHKLAEEALIVSKEKFRELFRNMRSGII CCCCEEHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE AVESDGKGFRVKSMNPAAERMEGVSCAAIQGMDLQEALPEIWNSPIRRALQEIRETGEAI EEECCCCCEEEECCCHHHHHHCCCCEEEECCCCHHHHHHHHHCHHHHHHHHHHHHCCCEE HCPEVECGEGWFDVHLHQLSTGEVVIICTDITLRKQYEDELRASLREKEALLREVHHRVK CCCCCCCCCCEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH NNFQVISSLINLQLDDAEDPAPLRDLQSRIQSMALVHELLYESEDLTSIDMGRYIERLTS HHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH SIVNSHHNGEIEVEVAVGDITLPLETAIPLGLIINELVTNSFKHAFTSGGMISVELEEHG HHHCCCCCCEEEEEEEECCEEECHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC GEFTLTITDNGVGLPPDFIIEDSDSLGLRLVAGLVDQIDGTLEVSGEDGTRFRLTFGVVP CEEEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCC YRRRV HHCCC >Mature Secondary Structure MNPMAIISITAFVVALVSGVYIFVKNPESRFNRALLLFSALIAYLSLTDFGLYISESYMM CCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH ADFWVRMGFLWPIVVPVILHMVLLFTGRRPTMPLLAVIYAPAVVIAALELTTDLITAGPT HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC MTSWGWTFSAAENSLPYQISNIWGFIIASVAIILVALHWRSSRGSDRTQAHYLLTGLILP CCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH VLAGVLTDLVLPAAGMAVPSLTDPSAALGVSIIAYGVMRFRLPILSPLNAAMDIVRNMNT HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCE FLIITDLGLNIHYVNPATERLTGRRAAEFSGRKVTEVLKFDELSTGSIMESRLRGKDEWI EEEEEECCCEEEEECCHHHHHCCCHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCE PVIVSAGHVHGSGGEHLGLLFTGSDMRPILEMEEKLRRREDRLVLLTEHMADGLGEFDRD EEEEEECEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEHHHHHCCHHHHCCC FNFRYLSPSVKKITGYDHEMLTGMSALDFMDYLHPDDTEEVKKLILTRGEGHRATFRIRR CCEEEECCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEEC PDGNYRWVEYVDRPIRTDGDIEGYVFGLRDIHEHKLAEEALIVSKEKFRELFRNMRSGII CCCCEEHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE AVESDGKGFRVKSMNPAAERMEGVSCAAIQGMDLQEALPEIWNSPIRRALQEIRETGEAI EEECCCCCEEEECCCHHHHHHCCCCEEEECCCCHHHHHHHHHCHHHHHHHHHHHHCCCEE HCPEVECGEGWFDVHLHQLSTGEVVIICTDITLRKQYEDELRASLREKEALLREVHHRVK CCCCCCCCCCEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH NNFQVISSLINLQLDDAEDPAPLRDLQSRIQSMALVHELLYESEDLTSIDMGRYIERLTS HHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH SIVNSHHNGEIEVEVAVGDITLPLETAIPLGLIINELVTNSFKHAFTSGGMISVELEEHG HHHCCCCCCEEEEEEEECCEEECHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC GEFTLTITDNGVGLPPDFIIEDSDSLGLRLVAGLVDQIDGTLEVSGEDGTRFRLTFGVVP CEEEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCC YRRRV HHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]