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Identifier: 15678171

GI number: 15678171

Start: 94759

End: 95400

Strand: Direct

Name: Not Available

Synonym: MTH143

Alternate gene names: 15678171

Gene position: 94759-95400 (Clockwise)

Preceding gene: 15678170

Following gene: 15678179

Centisome position: 5.41

GC content: 52.49

Gene sequence:

>642_bases
ATGAGAGTCCAAACTACCCGACCCTCAAATAATTATTTTTTTATGGAAATGAGTGAACTTGACTCTGTTGCTGTCCTCTG
CGGTGGCAGGGGAAGGCGGATGGGCTCAGATAAGGGACTTCTTCTCATGGATGACCGGCCCTTCATAGAGATCATAACAG
CAAAATTACTTGGACATTTCAGTGATGTCCTTGTGGTTCTGCGTGACACTGACCAGGCCGGGACCTACAGGGGCATCCTC
GATGACCGTGTGAGGATCCTGACGGATGAGCTGCCTGGTGCAGGACCCCTTGGAGGAATATACACTGCACTGGGGAATAT
ATCAGGGGATGCTGCGCTTTTCCTCCCCTGTGACGCGCCCCTTGTTACGGACGAGTTCCTGGTGAATATGAAGGAGTGCT
TCCGGAGGCTTGGGGATTCCTGTGACGCCATAGTACCATGGGGGGATGATGGACCGGAACCCCTCCATGCTGTGTACTCT
GCCAGGGTGAGGGGGACTGTGGAGGCGCTTCTATCCAAAAATAAAAGGAGAGTGGGGACTCTGATTGAATCCATTAACTC
CTGCCGCATAGCCGCAATCAGACTGGATCCGACACTTCAAAGCTTCAGGAACTTCAACCGTCCGGAGGATCTCAGGATCT
GA

Upstream 100 bases:

>100_bases
GTGCCGCTAACCTAAGTGAGATGAAGGAAAGGGCGAAGCTGGTCCGGATAACTTCAAGCGGGTATCAAGGAGAGCCACCC
CCACGACCTCCTCATAACCA

Downstream 100 bases:

>100_bases
TATCAACTGTGCGTGGATTCCTTCCCATCTCAAGAACAAACTTGTTTACACGCTCAATCATGTCGATGTAGTGTTCTTTA
TGGATTTTCTTCCCATCGAC

Product: molybdopterin-guanine dinucleotide biosynthesis MobA related protein

Products: molybdopterin guanine dinucleotide; pyrophosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MRVQTTRPSNNYFFMEMSELDSVAVLCGGRGRRMGSDKGLLLMDDRPFIEIITAKLLGHFSDVLVVLRDTDQAGTYRGIL
DDRVRILTDELPGAGPLGGIYTALGNISGDAALFLPCDAPLVTDEFLVNMKECFRRLGDSCDAIVPWGDDGPEPLHAVYS
ARVRGTVEALLSKNKRRVGTLIESINSCRIAAIRLDPTLQSFRNFNRPEDLRI

Sequences:

>Translated_213_residues
MRVQTTRPSNNYFFMEMSELDSVAVLCGGRGRRMGSDKGLLLMDDRPFIEIITAKLLGHFSDVLVVLRDTDQAGTYRGIL
DDRVRILTDELPGAGPLGGIYTALGNISGDAALFLPCDAPLVTDEFLVNMKECFRRLGDSCDAIVPWGDDGPEPLHAVYS
ARVRGTVEALLSKNKRRVGTLIESINSCRIAAIRLDPTLQSFRNFNRPEDLRI
>Mature_213_residues
MRVQTTRPSNNYFFMEMSELDSVAVLCGGRGRRMGSDKGLLLMDDRPFIEIITAKLLGHFSDVLVVLRDTDQAGTYRGIL
DDRVRILTDELPGAGPLGGIYTALGNISGDAALFLPCDAPLVTDEFLVNMKECFRRLGDSCDAIVPWGDDGPEPLHAVYS
ARVRGTVEALLSKNKRRVGTLIESINSCRIAAIRLDPTLQSFRNFNRPEDLRI

Specific function: Links a guanosine 5'-phosphate to molydopterin (MPT) forming molybdopterin guanine dinucleotide (MGD) [H]

COG id: COG0746

COG function: function code H; Molybdopterin-guanine dinucleotide biosynthesis protein A

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mobA family [H]

Homologues:

Organism=Escherichia coli, GI1790288, Length=194, Percent_Identity=27.319587628866, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013482 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 23560; Mature: 23560

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVQTTRPSNNYFFMEMSELDSVAVLCGGRGRRMGSDKGLLLMDDRPFIEIITAKLLGHF
CCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHH
SDVLVVLRDTDQAGTYRGILDDRVRILTDELPGAGPLGGIYTALGNISGDAALFLPCDAP
HHEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCC
LVTDEFLVNMKECFRRLGDSCDAIVPWGDDGPEPLHAVYSARVRGTVEALLSKNKRRVGT
CHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LIESINSCRIAAIRLDPTLQSFRNFNRPEDLRI
HHHHCCCCEEEEEEECHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRVQTTRPSNNYFFMEMSELDSVAVLCGGRGRRMGSDKGLLLMDDRPFIEIITAKLLGHF
CCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHH
SDVLVVLRDTDQAGTYRGILDDRVRILTDELPGAGPLGGIYTALGNISGDAALFLPCDAP
HHEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCC
LVTDEFLVNMKECFRRLGDSCDAIVPWGDDGPEPLHAVYSARVRGTVEALLSKNKRRVGT
CHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LIESINSCRIAAIRLDPTLQSFRNFNRPEDLRI
HHHHCCCCEEEEEEECHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: molybdopterin; GTP [C]

Specific reaction: molybdopterin + GTP = molybdopterin guanine dinucleotide + pyrophosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]