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Identifier: 15678166

GI number: 15678166

Start: 89372

End: 90526

Strand: Direct

Name: Not Available

Synonym: MTH138

Alternate gene names: 15678166

Gene position: 89372-90526 (Clockwise)

Preceding gene: 15678165

Following gene: 15678167

Centisome position: 5.1

GC content: 52.55

Gene sequence:

>1155_bases
TTGAGGAAACAGGGGGTTCATATGAGGATATGCATCGTTACGGAGTACTTCCCTGGAGGCGAGGAGCTGAACATCCGGGG
CGGTGCAGAGGCCTGTGCCTTCAACGAGGCCCTTAAACTGTCAGAGAAACATGAGGTCACGGTACTGACATCAAGGACCC
CTGAAAACCCTGAGAACTACAGATGCGGGAACATGGAGGTTATCTGCTGTGGCCCTGTGAGGTCCTATGTCCAGGCGGGT
TCAATCACAGGGAGACTCTCCTTCATGTTATCAGCATACCGTGAGGGATTAAAACTTGACCCTGACGCGGTGATTGGCTA
CAACTTCATAACACACCCCGTTGCCTGGATGATCGCAGGAAAAAGGAATGCTGCGGCACTGGCCCGCTACCATGACGTCT
GGATCGGGGAGTGGGTGAGGAACATAGGGGTTTCAGGCATCCTCGGTGAGCTGCTTGAGAGGTACACACTCTCACGGAGA
TTCGACAGGATAGTGGCGGTATCTGAGTACACAGCAGGCAAGATCCTTGAGAGGTATCCCTGGCAGCAGGTCTCTGTTGT
TCATAACATGGTCGACTTCAGGACACCTCCTGTCCGGAAAACCAGCACACCATCAATTGCATGTGTATCACGCCTTGTTG
AATACAAGAGGATCCAGGACCTCATAAGGGCGGTTTCGGTGATAAGGGAGAAGTTCCCTGATATAAGGTGCCGGATAATC
GGCACAGGTCCCCTTGAGGAGCGTTTAAGGGGTCTTGCACGTGAACTTGCTGTTGAGGATAACGTTGAGTTCATGGGCTT
CGTTGAGAAACACGCAGATGTACTGGAGGTTATAGCAGAGTCCTGGGTCTTCTGCCTTCCAAGCGTGGTTGAAGGCTTTG
GAATAGTTGTTGTGGAGGCCATGGGCTGCGGGACACCCTTCGTGGCTGCCAGGATACCCCCTGTAATGGAGTCAAGCCAG
GAGAAGGGAGGACTTTTCTTTGAACCCGGAAACTGGCGTGACCTTGCAGAGAAGCTTGAACTTTTGCTCTCCAGCGGAGA
GCTCCATGAAAGGTTAAGCTCTGAGGCTGCAGATGTTTTCAGGGACTACAGTGCAGATTCCATAGGTAGAAAGCTGGAGA
GAGTGCTGACGGAGGTCACAGGCAGGGATGAATGA

Upstream 100 bases:

>100_bases
GAGCCTATTACCTCCTTTTCAGGATATACCTCATGGTCGACAGGATCCAGCAGGACATAACCGAGCTTGTCCATGAAATC
GCCCTCAGGGAACATGATGA

Downstream 100 bases:

>100_bases
TTCCCCCCATGGGTGTATTCGTGGTTCTTTTTCTCAGGGCTGCTGACAACTATTAATAGTCAGGGAACATAACTGATATT
ATGGTTATCTACTTCAGAGG

Product: GlcNAc-phosphatidylinositol related biosynthetic protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MRKQGVHMRICIVTEYFPGGEELNIRGGAEACAFNEALKLSEKHEVTVLTSRTPENPENYRCGNMEVICCGPVRSYVQAG
SITGRLSFMLSAYREGLKLDPDAVIGYNFITHPVAWMIAGKRNAAALARYHDVWIGEWVRNIGVSGILGELLERYTLSRR
FDRIVAVSEYTAGKILERYPWQQVSVVHNMVDFRTPPVRKTSTPSIACVSRLVEYKRIQDLIRAVSVIREKFPDIRCRII
GTGPLEERLRGLARELAVEDNVEFMGFVEKHADVLEVIAESWVFCLPSVVEGFGIVVVEAMGCGTPFVAARIPPVMESSQ
EKGGLFFEPGNWRDLAEKLELLLSSGELHERLSSEAADVFRDYSADSIGRKLERVLTEVTGRDE

Sequences:

>Translated_384_residues
MRKQGVHMRICIVTEYFPGGEELNIRGGAEACAFNEALKLSEKHEVTVLTSRTPENPENYRCGNMEVICCGPVRSYVQAG
SITGRLSFMLSAYREGLKLDPDAVIGYNFITHPVAWMIAGKRNAAALARYHDVWIGEWVRNIGVSGILGELLERYTLSRR
FDRIVAVSEYTAGKILERYPWQQVSVVHNMVDFRTPPVRKTSTPSIACVSRLVEYKRIQDLIRAVSVIREKFPDIRCRII
GTGPLEERLRGLARELAVEDNVEFMGFVEKHADVLEVIAESWVFCLPSVVEGFGIVVVEAMGCGTPFVAARIPPVMESSQ
EKGGLFFEPGNWRDLAEKLELLLSSGELHERLSSEAADVFRDYSADSIGRKLERVLTEVTGRDE
>Mature_384_residues
MRKQGVHMRICIVTEYFPGGEELNIRGGAEACAFNEALKLSEKHEVTVLTSRTPENPENYRCGNMEVICCGPVRSYVQAG
SITGRLSFMLSAYREGLKLDPDAVIGYNFITHPVAWMIAGKRNAAALARYHDVWIGEWVRNIGVSGILGELLERYTLSRR
FDRIVAVSEYTAGKILERYPWQQVSVVHNMVDFRTPPVRKTSTPSIACVSRLVEYKRIQDLIRAVSVIREKFPDIRCRII
GTGPLEERLRGLARELAVEDNVEFMGFVEKHADVLEVIAESWVFCLPSVVEGFGIVVVEAMGCGTPFVAARIPPVMESSQ
EKGGLFFEPGNWRDLAEKLELLLSSGELHERLSSEAADVFRDYSADSIGRKLERVLTEVTGRDE

Specific function: Slime polysaccharide colanic acid biosynthesis. [C]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=171, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1788357, Length=190, Percent_Identity=33.6842105263158, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 43074; Mature: 43074

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKQGVHMRICIVTEYFPGGEELNIRGGAEACAFNEALKLSEKHEVTVLTSRTPENPENY
CCCCCCEEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
RCGNMEVICCGPVRSYVQAGSITGRLSFMLSAYREGLKLDPDAVIGYNFITHPVAWMIAG
CCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHEEC
KRNAAALARYHDVWIGEWVRNIGVSGILGELLERYTLSRRFDRIVAVSEYTAGKILERYP
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCC
WQQVSVVHNMVDFRTPPVRKTSTPSIACVSRLVEYKRIQDLIRAVSVIREKFPDIRCRII
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GTGPLEERLRGLARELAVEDNVEFMGFVEKHADVLEVIAESWVFCLPSVVEGFGIVVVEA
ECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
MGCGTPFVAARIPPVMESSQEKGGLFFEPGNWRDLAEKLELLLSSGELHERLSSEAADVF
CCCCCCHHHHCCCHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RDYSADSIGRKLERVLTEVTGRDE
HHCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRKQGVHMRICIVTEYFPGGEELNIRGGAEACAFNEALKLSEKHEVTVLTSRTPENPENY
CCCCCCEEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
RCGNMEVICCGPVRSYVQAGSITGRLSFMLSAYREGLKLDPDAVIGYNFITHPVAWMIAG
CCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHEEC
KRNAAALARYHDVWIGEWVRNIGVSGILGELLERYTLSRRFDRIVAVSEYTAGKILERYP
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCC
WQQVSVVHNMVDFRTPPVRKTSTPSIACVSRLVEYKRIQDLIRAVSVIREKFPDIRCRII
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
GTGPLEERLRGLARELAVEDNVEFMGFVEKHADVLEVIAESWVFCLPSVVEGFGIVVVEA
ECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
MGCGTPFVAARIPPVMESSQEKGGLFFEPGNWRDLAEKLELLLSSGELHERLSSEAADVF
CCCCCCHHHHCCCHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RDYSADSIGRKLERVLTEVTGRDE
HHCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]