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Identifier: 15678164

GI number: 15678164

Start: 88305

End: 88967

Strand: Direct

Name: Not Available

Synonym: MTH136

Alternate gene names: 15678164

Gene position: 88305-88967 (Clockwise)

Preceding gene: 15678163

Following gene: 15678165

Centisome position: 5.04

GC content: 52.34

Gene sequence:

>663_bases
GTGGAATTCATGGCTGAACACAGGCAAGAGGACGTTGCGGTTGTTGTACCTGTATACAATGAGGAGAAGACCGTGGCGGG
TGTCATAGAATCCCTCCTTGATAGGGGCTACAGGGTCATAGCCGTTGATGACGGCTCAAGGGATTCAACCCCTGAGATAC
TTGCAGGAATAGCATCTGAAAGGGATGGATTATCTGTTTACACCCACGTCATAAACAGGGGTCTCGGAACGGCCCTGAGG
ACTGGTCTGAGGGCGGCTGTGGATGAGGGGGCCTCCTGCATCGTCACCTTTGATGCGGATGGGCAGCATGACCCTGATGA
TATTGAGGGGGTCATCGAGCCCCTCCTGAAGGGGGAGGCCGATGTGGTGATAGGTAGCCGGGACTTCTCTGAGATGCCCC
TTTCAAGGAGCCTCGGGAACACCCTAATGAACCTGCTGACCCTCCTGTTCTATGGTTGCAGGGTTTCAGATTCCCAGTCT
GGTCTGAGGGCATTCACAGCCAGGGCAGCATCAGTCATTGATATAAAGAGCAGAGGTTACGGTGTTTCATCCGAGATAAT
AGGTGAGATACACAGAAATGGTCTCAGGATGAGGGAGGTTACAATAAAGACGATATACACTCCCGAGACAATATCCAAGG
GACCAGCACCTCAGTGGGTATAA

Upstream 100 bases:

>100_bases
TCAGCCGATGACATGACAGGTATCGAAACAGCAAGGAACCTTGGAAGGAGGGTCGCCCTCCTTGCAGCAAGGATCCATGG
CTGAATCCAGAACTATCTGA

Downstream 100 bases:

>100_bases
GGATACTTCTGAGGCTGATCCTGAACATGCTTAGAAGGTTTAAACAGGAGATCAGCTGTGAGATCCAGTGTTGGTGAGTT
TATGATATATCAGGTTATTG

Product: dolichyl-phosphate mannose synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MEFMAEHRQEDVAVVVPVYNEEKTVAGVIESLLDRGYRVIAVDDGSRDSTPEILAGIASERDGLSVYTHVINRGLGTALR
TGLRAAVDEGASCIVTFDADGQHDPDDIEGVIEPLLKGEADVVIGSRDFSEMPLSRSLGNTLMNLLTLLFYGCRVSDSQS
GLRAFTARAASVIDIKSRGYGVSSEIIGEIHRNGLRMREVTIKTIYTPETISKGPAPQWV

Sequences:

>Translated_220_residues
MEFMAEHRQEDVAVVVPVYNEEKTVAGVIESLLDRGYRVIAVDDGSRDSTPEILAGIASERDGLSVYTHVINRGLGTALR
TGLRAAVDEGASCIVTFDADGQHDPDDIEGVIEPLLKGEADVVIGSRDFSEMPLSRSLGNTLMNLLTLLFYGCRVSDSQS
GLRAFTARAASVIDIKSRGYGVSSEIIGEIHRNGLRMREVTIKTIYTPETISKGPAPQWV
>Mature_220_residues
MEFMAEHRQEDVAVVVPVYNEEKTVAGVIESLLDRGYRVIAVDDGSRDSTPEILAGIASERDGLSVYTHVINRGLGTALR
TGLRAAVDEGASCIVTFDADGQHDPDDIEGVIEPLLKGEADVVIGSRDFSEMPLSRSLGNTLMNLLTLLFYGCRVSDSQS
GLRAFTARAASVIDIKSRGYGVSSEIIGEIHRNGLRMREVTIKTIYTPETISKGPAPQWV

Specific function: Unknown

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787259, Length=109, Percent_Identity=37.6146788990826, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: NA

Molecular weight: Translated: 23853; Mature: 23853

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFMAEHRQEDVAVVVPVYNEEKTVAGVIESLLDRGYRVIAVDDGSRDSTPEILAGIASE
CCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCC
RDGLSVYTHVINRGLGTALRTGLRAAVDEGASCIVTFDADGQHDPDDIEGVIEPLLKGEA
CCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
DVVIGSRDFSEMPLSRSLGNTLMNLLTLLFYGCRVSDSQSGLRAFTARAASVIDIKSRGY
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEECCCCC
GVSSEIIGEIHRNGLRMREVTIKTIYTPETISKGPAPQWV
CCHHHHHHHHHHCCCEEEEEEEEEEECCHHCCCCCCCCCC
>Mature Secondary Structure
MEFMAEHRQEDVAVVVPVYNEEKTVAGVIESLLDRGYRVIAVDDGSRDSTPEILAGIASE
CCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCC
RDGLSVYTHVINRGLGTALRTGLRAAVDEGASCIVTFDADGQHDPDDIEGVIEPLLKGEA
CCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
DVVIGSRDFSEMPLSRSLGNTLMNLLTLLFYGCRVSDSQSGLRAFTARAASVIDIKSRGY
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEECCCCC
GVSSEIIGEIHRNGLRMREVTIKTIYTPETISKGPAPQWV
CCHHHHHHHHHHCCCEEEEEEEEEEECCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]