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Identifier: 15678162

GI number: 15678162

Start: 87219

End: 87680

Strand: Direct

Name: Not Available

Synonym: MTH134

Alternate gene names: 15678162

Gene position: 87219-87680 (Clockwise)

Preceding gene: 15678161

Following gene: 15678163

Centisome position: 4.98

GC content: 52.6

Gene sequence:

>462_bases
ATGATAAAGGTCGGGATCTGCGATACAACCTTTGCAAGGTATGATATGGGCGGAGCTGCAATCGATGAGCTGAAGAAGCA
CACTGCAGGTATAAAGATCATAAGGAGGACCGTCCCCGGGATAAAGGACCTTCCGGTGGCCTGCAAGAAACTCATAGAGG
AGGAGGGCTGTGAGATGGTCATGGCCCTCGGGATGCCAGGTCCAGAGGAGAAGGATAAAGTATGCGCCCACGAGGCATCC
ACGGGTCTCATACAGGCCCAGCTCATGACGAACACCCACATACTTGAGGTATTTGTACATGAGGATGAGGAGGATGACCC
TGAAGAACTCAAGGTCCTTGCAGATAACAGGGCAAGGGAACATGCCCAGAACCTCATCATGATGCTATTTAAACCAGACA
GGCTTACACGTGAGGCCGGTATGGGTCTGCGTGAGGGCAAACCCGATGCCGGGCCACTTTAA

Upstream 100 bases:

>100_bases
TACTCCAGAAGGAGGATGACCTTCCCTTTGAGGAGCCCTACCCCCTGACAATAGGGGAGGCCCGGAGGAAACTCCGTAAC
CAGCTCAGATAGGTGATTTC

Downstream 100 bases:

>100_bases
TGAAACAGAAGGAGGTTGATTTCATGGTTAAGGTTATTGGAATCTGTGGAAGTCCAAGAAAGAATGGTAACACCGAGATA
CTCCTCAGGGAGGCTCTTGA

Product: riboflavin synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MIKVGICDTTFARYDMGGAAIDELKKHTAGIKIIRRTVPGIKDLPVACKKLIEEEGCEMVMALGMPGPEEKDKVCAHEAS
TGLIQAQLMTNTHILEVFVHEDEEDDPEELKVLADNRAREHAQNLIMMLFKPDRLTREAGMGLREGKPDAGPL

Sequences:

>Translated_153_residues
MIKVGICDTTFARYDMGGAAIDELKKHTAGIKIIRRTVPGIKDLPVACKKLIEEEGCEMVMALGMPGPEEKDKVCAHEAS
TGLIQAQLMTNTHILEVFVHEDEEDDPEELKVLADNRAREHAQNLIMMLFKPDRLTREAGMGLREGKPDAGPL
>Mature_153_residues
MIKVGICDTTFARYDMGGAAIDELKKHTAGIKIIRRTVPGIKDLPVACKKLIEEEGCEMVMALGMPGPEEKDKVCAHEAS
TGLIQAQLMTNTHILEVFVHEDEEDDPEELKVLADNRAREHAQNLIMMLFKPDRLTREAGMGLREGKPDAGPL

Specific function: Unknown

COG id: COG1731

COG function: function code H; Archaeal riboflavin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISC_METTH (O26237)

Other databases:

- EMBL:   AE000666
- PIR:   B69045
- RefSeq:   NP_275277.1
- ProteinModelPortal:   O26237
- SMR:   O26237
- STRING:   O26237
- GeneID:   1470095
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH134
- NMPDR:   fig|187420.1.peg.132
- eggNOG:   arNOG09515
- HOGENOM:   HBG297721
- OMA:   GTGQRQG
- ProtClustDB:   PRK06455
- BioCyc:   MTHE187420:MTH134-MONOMER
- BRENDA:   2.5.1.9
- InterPro:   IPR002180
- InterPro:   IPR006399
- Gene3D:   G3DSA:3.40.50.960
- PIRSF:   PIRSF015750
- TIGRFAMs:   TIGR01506

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16909; Mature: 16909

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVGICDTTFARYDMGGAAIDELKKHTAGIKIIRRTVPGIKDLPVACKKLIEEEGCEMV
CEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEE
MALGMPGPEEKDKVCAHEASTGLIQAQLMTNTHILEVFVHEDEEDDPEELKVLADNRARE
EECCCCCCCCHHHHHHHHCCCCEEEEHHHCCCEEEEEEEECCCCCCHHHHHHHHCCHHHH
HAQNLIMMLFKPDRLTREAGMGLREGKPDAGPL
HHHHHHHHEECCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MIKVGICDTTFARYDMGGAAIDELKKHTAGIKIIRRTVPGIKDLPVACKKLIEEEGCEMV
CEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEE
MALGMPGPEEKDKVCAHEASTGLIQAQLMTNTHILEVFVHEDEEDDPEELKVLADNRARE
EECCCCCCCCHHHHHHHHCCCCEEEEHHHCCCEEEEEEEECCCCCCHHHHHHHHCCHHHH
HAQNLIMMLFKPDRLTREAGMGLREGKPDAGPL
HHHHHHHHEECCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463