Click here to switch to the map view.

The map label for this gene is rps4p

Identifier: 15678065

GI number: 15678065

Start: 18114

End: 18629

Strand: Direct

Name: rps4p

Synonym: MTH35

Alternate gene names: 15678065

Gene position: 18114-18629 (Clockwise)

Preceding gene: 15678064

Following gene: 15678066

Centisome position: 1.03

GC content: 52.71

Gene sequence:

>516_bases
ATGGGACACCCACGTAAGGCAAGGAAAAAGTATGATACTCCACCTCACCCATGGAACGCTGAAAGAATAAAGGAAGAAAA
CAGGCTCGTGGCAAAATACGGCCTCAAGAACAAGAAGGAAGTCTGGAAAGCAGAGACAATGGTGAGGAGATACAGGAGGG
ACGCAAGGTACCTCCTTGGTATGGCCAGTGAACACACAGGGAAGGAGAGGGAACAGCTCCTGGGCCACCTCGTCAGGACA
GGAATACTCAACGAGGGCGCCAAACTCGAGGACGTCCTGGACCTCACAGTGGAGGACGTGCTCAGGAGAAGACTCCAGAC
ACTGGTCCACAAGAGGGGACTTGCAAGGACCGTGAAGGAGGCCAGGCAGATGGTCATCCACGGCCACATAGCCCTTGACG
GAAGGAAGATCGACGCCCCGGGATACATAGTTAAAAGGGGAGAAGAGGATAAGATAGGGTTCTACCCATCATCCCCAATG
AAAAAACAGATAGAAGCAGCCCAGGACGCTGAATAA

Upstream 100 bases:

>100_bases
CTTGGACTACCTGTCAGGGGACAGAGGACAAAGTCAACATTTAGGAAAGGCTCCTCAGTTGGTGTGAGAAGGAAGAAGAG
ATAGTTAAGGAGATGTTAAA

Downstream 100 bases:

>100_bases
TTTCAGGGAGAGATAAAATGGCTGAGAAGGAAAAATGGGGAATTGCAAATATTTACTCATCATTCAACAACACAATAATC
ACCATCACAGACATAACCGG

Product: 30S ribosomal protein S4P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MGHPRKARKKYDTPPHPWNAERIKEENRLVAKYGLKNKKEVWKAETMVRRYRRDARYLLGMASEHTGKEREQLLGHLVRT
GILNEGAKLEDVLDLTVEDVLRRRLQTLVHKRGLARTVKEARQMVIHGHIALDGRKIDAPGYIVKRGEEDKIGFYPSSPM
KKQIEAAQDAE

Sequences:

>Translated_171_residues
MGHPRKARKKYDTPPHPWNAERIKEENRLVAKYGLKNKKEVWKAETMVRRYRRDARYLLGMASEHTGKEREQLLGHLVRT
GILNEGAKLEDVLDLTVEDVLRRRLQTLVHKRGLARTVKEARQMVIHGHIALDGRKIDAPGYIVKRGEEDKIGFYPSSPM
KKQIEAAQDAE
>Mature_170_residues
GHPRKARKKYDTPPHPWNAERIKEENRLVAKYGLKNKKEVWKAETMVRRYRRDARYLLGMASEHTGKEREQLLGHLVRTG
ILNEGAKLEDVLDLTVEDVLRRRLQTLVHKRGLARTVKEARQMVIHGHIALDGRKIDAPGYIVKRGEEDKIGFYPSSPMK
KQIEAAQDAE

Specific function: With S5 and S12 plays an important role in translational accuracy

COG id: COG0522

COG function: function code J; Ribosomal protein S4 and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain

Homologues:

Organism=Homo sapiens, GI14141193, Length=156, Percent_Identity=38.4615384615385, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17535707, Length=150, Percent_Identity=38.6666666666667, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6325176, Length=160, Percent_Identity=40, Blast_Score=112, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319666, Length=160, Percent_Identity=39.375, Blast_Score=111, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6321942, Length=165, Percent_Identity=26.6666666666667, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24661711, Length=160, Percent_Identity=36.25, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24661707, Length=160, Percent_Identity=36.25, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24661715, Length=130, Percent_Identity=40, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RS4_METTH (O26142)

Other databases:

- EMBL:   AE000666
- PIR:   A69145
- RefSeq:   NP_275179.1
- ProteinModelPortal:   O26142
- SMR:   O26142
- STRING:   O26142
- GeneID:   1469997
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH35
- NMPDR:   fig|187420.1.peg.34
- eggNOG:   arNOG08837
- HOGENOM:   HBG588353
- OMA:   RNKRELW
- PhylomeDB:   O26142
- ProtClustDB:   PRK04051
- BioCyc:   MTHE187420:MTH35-MONOMER
- GO:   GO:0006412
- HAMAP:   MF_01306_A
- InterPro:   IPR022801
- InterPro:   IPR005710
- InterPro:   IPR022802
- InterPro:   IPR018079
- InterPro:   IPR002942
- PANTHER:   PTHR11831
- SMART:   SM00363
- TIGRFAMs:   TIGR01018

Pfam domain/function: PF01479 S4

EC number: NA

Molecular weight: Translated: 19798; Mature: 19667

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: PS00632 RIBOSOMAL_S4; PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHPRKARKKYDTPPHPWNAERIKEENRLVAKYGLKNKKEVWKAETMVRRYRRDARYLLG
CCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MASEHTGKEREQLLGHLVRTGILNEGAKLEDVLDLTVEDVLRRRLQTLVHKRGLARTVKE
HHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQMVIHGHIALDGRKIDAPGYIVKRGEEDKIGFYPSSPMKKQIEAAQDAE
HHHHHHHHHEEECCEEECCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
GHPRKARKKYDTPPHPWNAERIKEENRLVAKYGLKNKKEVWKAETMVRRYRRDARYLLG
CCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
MASEHTGKEREQLLGHLVRTGILNEGAKLEDVLDLTVEDVLRRRLQTLVHKRGLARTVKE
HHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQMVIHGHIALDGRKIDAPGYIVKRGEEDKIGFYPSSPMKKQIEAAQDAE
HHHHHHHHHEEECCEEECCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463