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The map label for this gene is purR

Identifier: 15674241

GI number: 15674241

Start: 2351004

End: 2351819

Strand: Reverse

Name: purR

Synonym: L134453

Alternate gene names: 15674241

Gene position: 2351819-2351004 (Counterclockwise)

Preceding gene: 15674242

Following gene: 15674236

Centisome position: 99.42

GC content: 35.66

Gene sequence:

>816_bases
ATGAAAAGAAACGAACGTTTAGTTGATTTTACAAATTTTTTAATTAATCATCCCAATCAAATGCTAAATTTAAATGAATT
AAGTAAACATTATGAGGTAGCCAAATCATCTATCTCAGAAGATTTAGTATTTATCAAACGTGTTTTTGAAAACCAAGGAG
TAGGTCTGGTTGAAACTTTCCCAGGTAGCCTTGGAGGAGTTCGGTTTACGCCTTACATTACTGACGAACGTTCGTTGGAA
ATGAGTCAGGAAATTGCTGAACTTTTACGTGAAGAAAATCGAATTTTACCTGGAGGATATATTTATCTGTCAGATATTTT
GGGTACTCCATCAAATCTTCGTAAAATCGGTCAAATTATTGCTCATGAGTATCATGAAAAGCAAGTTGATGTCGTCATGA
CTATTGCCACAAAAGGGATTCCAATTGCTCAGTCAGTTGCTGAGATTCTAGATGTTCCTTTCGTAATTGTTCGTCGTGAC
CCTAAAGTGACCGAAGGAGCAACGCTCAATGTAAATTATATGTCAGGTTCAAGCTCTCGTGTTGAAAATATGACTTTATC
CAAACGGAGTCTTTCAATTGGTCAAAATGTTTTGATCGTTGATGACTTCATGAAAGGCGCAGGAACAATCAATGGAATGA
GAAGTCTTGTCCATGAATTTGATTGTTTACTTGCCGGTGTTGCCGTCTTTCTTGAGGGACCTTTTAAAGGAGAACGATTG
ATTGATGATTACAAATCAATCTTGAAAGTTGATCGAATTGATATTGCTAACCGCTCAATTGATGTTCAATTGGGAAATAT
ATTTAATGACAAATAA

Upstream 100 bases:

>100_bases
ATGAATCTGAAATCTGTCAGTAAAATTGTTTCATGTGAAACTTGAATGTTCGGAAATGCCATGCTATAATAAGCTTATCA
AATAGGAGATGAGATAATAA

Downstream 100 bases:

>100_bases
AAAAGTTACTGACAGGACATTCTGTCAGTAACTTTTTCTATTTATTCACTTAAAAGAAAGAAATTTTGTTGAGTGGCCAC
ACTCGTAATTTCGCTTCACC

Product: pur operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MKRNERLVDFTNFLINHPNQMLNLNELSKHYEVAKSSISEDLVFIKRVFENQGVGLVETFPGSLGGVRFTPYITDERSLE
MSQEIAELLREENRILPGGYIYLSDILGTPSNLRKIGQIIAHEYHEKQVDVVMTIATKGIPIAQSVAEILDVPFVIVRRD
PKVTEGATLNVNYMSGSSSRVENMTLSKRSLSIGQNVLIVDDFMKGAGTINGMRSLVHEFDCLLAGVAVFLEGPFKGERL
IDDYKSILKVDRIDIANRSIDVQLGNIFNDK

Sequences:

>Translated_271_residues
MKRNERLVDFTNFLINHPNQMLNLNELSKHYEVAKSSISEDLVFIKRVFENQGVGLVETFPGSLGGVRFTPYITDERSLE
MSQEIAELLREENRILPGGYIYLSDILGTPSNLRKIGQIIAHEYHEKQVDVVMTIATKGIPIAQSVAEILDVPFVIVRRD
PKVTEGATLNVNYMSGSSSRVENMTLSKRSLSIGQNVLIVDDFMKGAGTINGMRSLVHEFDCLLAGVAVFLEGPFKGERL
IDDYKSILKVDRIDIANRSIDVQLGNIFNDK
>Mature_271_residues
MKRNERLVDFTNFLINHPNQMLNLNELSKHYEVAKSSISEDLVFIKRVFENQGVGLVETFPGSLGGVRFTPYITDERSLE
MSQEIAELLREENRILPGGYIYLSDILGTPSNLRKIGQIIAHEYHEKQVDVVMTIATKGIPIAQSVAEILDVPFVIVRRD
PKVTEGATLNVNYMSGSSSRVENMTLSKRSLSIGQNVLIVDDFMKGAGTINGMRSLVHEFDCLLAGVAVFLEGPFKGERL
IDDYKSILKVDRIDIANRSIDVQLGNIFNDK

Specific function: Controls the transcription of the pur operon for purine biosynthetic genes

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURR_LACLA (P0A3Z9)

Other databases:

- EMBL:   AE005176
- PIR:   C86907
- RefSeq:   NP_268416.1
- ProteinModelPortal:   P0A3Z9
- SMR:   P0A3Z9
- GeneID:   1115937
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L134453
- NMPDR:   fig|272623.1.peg.2314
- HOGENOM:   HBG304155
- OMA:   EQQGIGT
- ProtClustDB:   PRK09213
- BioCyc:   LLAC272623:L134453-MONOMER
- GO:   GO:0006350
- InterPro:   IPR000836
- InterPro:   IPR015265
- InterPro:   IPR010078
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD029816
- TIGRFAMs:   TIGR01743

Pfam domain/function: PF00156 Pribosyltran; PF09182 PuR_N

EC number: NA

Molecular weight: Translated: 30361; Mature: 30361

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRNERLVDFTNFLINHPNQMLNLNELSKHYEVAKSSISEDLVFIKRVFENQGVGLVETF
CCCCCHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PGSLGGVRFTPYITDERSLEMSQEIAELLREENRILPGGYIYLSDILGTPSNLRKIGQII
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHCCCHHHHHHHHHH
AHEYHEKQVDVVMTIATKGIPIAQSVAEILDVPFVIVRRDPKVTEGATLNVNYMSGSSSR
HHHHHHHHHEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCCH
VENMTLSKRSLSIGQNVLIVDDFMKGAGTINGMRSLVHEFDCLLAGVAVFLEGPFKGERL
HHHHHHHHHHHHCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IDDYKSILKVDRIDIANRSIDVQLGNIFNDK
HHHHHHHHHHHHHEECCCEEEEEECCCCCCC
>Mature Secondary Structure
MKRNERLVDFTNFLINHPNQMLNLNELSKHYEVAKSSISEDLVFIKRVFENQGVGLVETF
CCCCCHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
PGSLGGVRFTPYITDERSLEMSQEIAELLREENRILPGGYIYLSDILGTPSNLRKIGQII
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHCCCHHHHHHHHHH
AHEYHEKQVDVVMTIATKGIPIAQSVAEILDVPFVIVRRDPKVTEGATLNVNYMSGSSSR
HHHHHHHHHEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCCH
VENMTLSKRSLSIGQNVLIVDDFMKGAGTINGMRSLVHEFDCLLAGVAVFLEGPFKGERL
HHHHHHHHHHHHCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IDDYKSILKVDRIDIANRSIDVQLGNIFNDK
HHHHHHHHHHHHHEECCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471