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The map label for this gene is nusG

Identifier: 15674086

GI number: 15674086

Start: 2173872

End: 2174429

Strand: Reverse

Name: nusG

Synonym: L157316

Alternate gene names: 15674086

Gene position: 2174429-2173872 (Counterclockwise)

Preceding gene: 15674087

Following gene: 15674085

Centisome position: 91.92

GC content: 36.74

Gene sequence:

>558_bases
ATGGAAGATAATAATTTAGTAAGTTTTGACCAAGGTTGGTTCGTTATTCAAACCTATGCAGGGTATGAACGTAAAGTTAA
AGAAGATTTGCTTGAGCGTGCTGAACTTTATAACATGGCTGACAAAATTTTGCGTGTCGAAATTCCAACTGAGACAATTC
GTACAGAAGTTAACGGCAAAATGAAAGAAGTTGAAGAAAACTTATTCCCAGGTTATGTTTTGGTTGAAATGAATATGACT
GATGAAGCCTGGTTTATTGTCCGTAATACACCAAATGTTACTGGATTCGTTGGTTCACACGGGAATAGATCAAAACCTAC
ACCACTTTTTGAACAAGAAATTCAAGATATTTTGGTTGGCATGGGCAAAGTTGTTCGTGAAATTGACTTTGATGTTTTTG
TTGGAAAACGTGTTCGTATTGTTGATGGTGCCTTTTCAGGATTTGAAGCTCCAATCACAGAAATCAATGGCGACAAATTG
ACTCTGACTGTTGATATGTTTGGTCGTGCAACTCCAGTTGAATTGGACATGCACCAAATTGAAGATATTCAAGCTTAA

Upstream 100 bases:

>100_bases
AGGGCTTGCCCCTTTTTCTTGTACCCAAATTACTGACAGATTTCTGTCAGCTGGGATTTTAACTGATTAAGTAAAAAAAA
TAAATACAGAGGTATTTCAA

Downstream 100 bases:

>100_bases
TTAAGTATTATAATAAAAAAAGCCACGAGAATTCGTGGCTTTTTGCGAGTTTACAGAATATTTGTTATAATTATAAAAAA
TGTGATTGGGGAATAAATAT

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MEDNNLVSFDQGWFVIQTYAGYERKVKEDLLERAELYNMADKILRVEIPTETIRTEVNGKMKEVEENLFPGYVLVEMNMT
DEAWFIVRNTPNVTGFVGSHGNRSKPTPLFEQEIQDILVGMGKVVREIDFDVFVGKRVRIVDGAFSGFEAPITEINGDKL
TLTVDMFGRATPVELDMHQIEDIQA

Sequences:

>Translated_185_residues
MEDNNLVSFDQGWFVIQTYAGYERKVKEDLLERAELYNMADKILRVEIPTETIRTEVNGKMKEVEENLFPGYVLVEMNMT
DEAWFIVRNTPNVTGFVGSHGNRSKPTPLFEQEIQDILVGMGKVVREIDFDVFVGKRVRIVDGAFSGFEAPITEINGDKL
TLTVDMFGRATPVELDMHQIEDIQA
>Mature_185_residues
MEDNNLVSFDQGWFVIQTYAGYERKVKEDLLERAELYNMADKILRVEIPTETIRTEVNGKMKEVEENLFPGYVLVEMNMT
DEAWFIVRNTPNVTGFVGSHGNRSKPTPLFEQEIQDILVGMGKVVREIDFDVFVGKRVRIVDGAFSGFEAPITEINGDKL
TLTVDMFGRATPVELDMHQIEDIQA

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain

Homologues:

Organism=Escherichia coli, GI1790414, Length=173, Percent_Identity=37.5722543352601, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUSG_LACLA (Q9CDV7)

Other databases:

- EMBL:   AE005176
- PIR:   H86887
- RefSeq:   NP_268261.1
- ProteinModelPortal:   Q9CDV7
- SMR:   Q9CDV7
- GeneID:   1115781
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L157316
- NMPDR:   fig|272623.1.peg.2159
- HOGENOM:   HBG751162
- OMA:   GVERPKP
- ProtClustDB:   PRK05609
- BioCyc:   LLAC272623:L157316-MONOMER
- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.30.30.30
- Gene3D:   G3DSA:3.30.70.940
- PRINTS:   PR00338
- SMART:   SM00739
- SMART:   SM00738
- TIGRFAMs:   TIGR00922

Pfam domain/function: PF00467 KOW; PF02357 NusG; SSF82679 Transcrpt_antiterm_NusG_N; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21110; Mature: 21110

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDNNLVSFDQGWFVIQTYAGYERKVKEDLLERAELYNMADKILRVEIPTETIRTEVNGK
CCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHCCCH
MKEVEENLFPGYVLVEMNMTDEAWFIVRNTPNVTGFVGSHGNRSKPTPLFEQEIQDILVG
HHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHH
MGKVVREIDFDVFVGKRVRIVDGAFSGFEAPITEINGDKLTLTVDMFGRATPVELDMHQI
HHHHHHHHCCEEEECCEEEEEECCCCCCCCCCEECCCCEEEEEEEECCCCCCEEECHHHH
EDIQA
HCCCC
>Mature Secondary Structure
MEDNNLVSFDQGWFVIQTYAGYERKVKEDLLERAELYNMADKILRVEIPTETIRTEVNGK
CCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHCCCH
MKEVEENLFPGYVLVEMNMTDEAWFIVRNTPNVTGFVGSHGNRSKPTPLFEQEIQDILVG
HHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHH
MGKVVREIDFDVFVGKRVRIVDGAFSGFEAPITEINGDKLTLTVDMFGRATPVELDMHQI
HHHHHHHHCCEEEECCEEEEEECCCCCCCCCCEECCCCEEEEEEEECCCCCCEEECHHHH
EDIQA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471