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The map label for this gene is secY

Identifier: 15674060

GI number: 15674060

Start: 2158067

End: 2159386

Strand: Reverse

Name: secY

Synonym: L0333

Alternate gene names: 15674060

Gene position: 2159386-2158067 (Counterclockwise)

Preceding gene: 15674061

Following gene: 15674059

Centisome position: 91.28

GC content: 38.41

Gene sequence:

>1320_bases
ATGTTTTTTAAGACGCTTAAGGAAGCCTTTAAGGTCAAGGACGTCCGAGCAAGAATTCTCTTTACGATTTTCATCCTTTT
TGTTTTCCGCTTAGGTGCTCATATTACGGTACCTGGCGTCAACGTTCAAAACTTGACAGAAGTAAGTAATCTTCCTTTCT
TGAACATGATGAACTTGGTTTCTGGTAATGCCATGCAAAACTACTCACTTTTTGCAATGGGGGTTTCGCCTTATATTACT
GCTTCAATCATTGTTCAATTGTTGCAAATGGATATTTTACCAAAATTTGTTGAGTGGTCAAAACAAGGGGAAATTGGACG
TCGTAAACTGAATCAAGCGACACGTTACATTACCTTAGTGCTTGCTATGGCACAATCTATCGGGATTACTGCTGGTTTCC
AAGCCATGAGCTCGTTAAATATTGTGCAAAATCCAAATTGGCAAAGCTATTTGATGATTGGTGCAATTTTGACCACTGGT
TCAATGGTTGTCACTTGGATGGGTGAACAAATTAATGAAAAAGGATTTGGTTCAGGTGTTTCAGTAATTATCTTTGCTGG
GATTGTATCTAGTATCCCATCGGCGGTCAAATCTGTTTATGATGAAAAATTCTTAAACGTTCGACCTTCAGAAATTCCAA
TGTCTTGGTTATTTGTCATTGGTCTAGTATTGTCAGCAATTATCATTATTTATGTAACAACTTTTGTTCAACAAGCAGAA
CGTAAAGTACCTATTCAATATACTAAATTAACTCAAGGTGCACCAACAAGTTCTTATTTGCCACTTCGTGTCAATCCAGC
TGGGGTTATCCCAGTTATCTTTGCTGGTTCAATTACAACTGCTCCAGCTACGATTTTGCAATTCTTGCAACGTTCGCAAG
GAAGTAATGTAGGTTGGTTATCAACTTTACAAGACGCCTTGTCATATACGACTTGGACAGGAATGCTCTTCTACGCATTA
TTGATTGTGCTCTTTACATTCTTCTACTCATTCGTTCAGGTCAATCCTGAAAAGATGGCTGAAAACCTTCAAAAACAAGG
CTCTTACATTCCATCTGTTCGTCCGGGTAAAGGAACCGAAAAGTATGTATCACGTCTCTTAATGCGTCTTGCAACGGTAG
GTGCGCTCTTCCTTGGTTTGATTTCAATCATTCCAATTGCCGCCCAAAACGTTTGGGGACTTCCAAAAATTGTCGCTCTT
GGAGGAACATCACTCTTAATCTTGATTCAAGTTGCTATACAAGCAGTGAAACAACTTGAAGGATATTTACTCAAACGTAA
ATATGCAGGATTTATGGATAATCCACTTGAAACAAAATAA

Upstream 100 bases:

>100_bases
GTGGTTCTGTAGAAGAAGCTTAATTTTTACACTACAATTGGCGGTTGAATTTTCAACCGCTTATTGTCTATTTACAATTA
AAACGCTTTAAGGAGATTTT

Downstream 100 bases:

>100_bases
AATCTTGTCATTAGACAAGGTTTTTCTTTATTTTTTAGCAAAAATACGCTAAAATAGTGTAGGTAAAATCACAGAGAACA
TCTGCAATTTACTGACAGTT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MFFKTLKEAFKVKDVRARILFTIFILFVFRLGAHITVPGVNVQNLTEVSNLPFLNMMNLVSGNAMQNYSLFAMGVSPYIT
ASIIVQLLQMDILPKFVEWSKQGEIGRRKLNQATRYITLVLAMAQSIGITAGFQAMSSLNIVQNPNWQSYLMIGAILTTG
SMVVTWMGEQINEKGFGSGVSVIIFAGIVSSIPSAVKSVYDEKFLNVRPSEIPMSWLFVIGLVLSAIIIIYVTTFVQQAE
RKVPIQYTKLTQGAPTSSYLPLRVNPAGVIPVIFAGSITTAPATILQFLQRSQGSNVGWLSTLQDALSYTTWTGMLFYAL
LIVLFTFFYSFVQVNPEKMAENLQKQGSYIPSVRPGKGTEKYVSRLLMRLATVGALFLGLISIIPIAAQNVWGLPKIVAL
GGTSLLILIQVAIQAVKQLEGYLLKRKYAGFMDNPLETK

Sequences:

>Translated_439_residues
MFFKTLKEAFKVKDVRARILFTIFILFVFRLGAHITVPGVNVQNLTEVSNLPFLNMMNLVSGNAMQNYSLFAMGVSPYIT
ASIIVQLLQMDILPKFVEWSKQGEIGRRKLNQATRYITLVLAMAQSIGITAGFQAMSSLNIVQNPNWQSYLMIGAILTTG
SMVVTWMGEQINEKGFGSGVSVIIFAGIVSSIPSAVKSVYDEKFLNVRPSEIPMSWLFVIGLVLSAIIIIYVTTFVQQAE
RKVPIQYTKLTQGAPTSSYLPLRVNPAGVIPVIFAGSITTAPATILQFLQRSQGSNVGWLSTLQDALSYTTWTGMLFYAL
LIVLFTFFYSFVQVNPEKMAENLQKQGSYIPSVRPGKGTEKYVSRLLMRLATVGALFLGLISIIPIAAQNVWGLPKIVAL
GGTSLLILIQVAIQAVKQLEGYLLKRKYAGFMDNPLETK
>Mature_439_residues
MFFKTLKEAFKVKDVRARILFTIFILFVFRLGAHITVPGVNVQNLTEVSNLPFLNMMNLVSGNAMQNYSLFAMGVSPYIT
ASIIVQLLQMDILPKFVEWSKQGEIGRRKLNQATRYITLVLAMAQSIGITAGFQAMSSLNIVQNPNWQSYLMIGAILTTG
SMVVTWMGEQINEKGFGSGVSVIIFAGIVSSIPSAVKSVYDEKFLNVRPSEIPMSWLFVIGLVLSAIIIIYVTTFVQQAE
RKVPIQYTKLTQGAPTSSYLPLRVNPAGVIPVIFAGSITTAPATILQFLQRSQGSNVGWLSTLQDALSYTTWTGMLFYAL
LIVLFTFFYSFVQVNPEKMAENLQKQGSYIPSVRPGKGTEKYVSRLLMRLATVGALFLGLISIIPIAAQNVWGLPKIVAL
GGTSLLILIQVAIQAVKQLEGYLLKRKYAGFMDNPLETK

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family

Homologues:

Organism=Escherichia coli, GI1789696, Length=423, Percent_Identity=38.2978723404255, Blast_Score=255, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECY_LACLA (P58118)

Other databases:

- EMBL:   AE005176
- PIR:   F86884
- RefSeq:   NP_268235.1
- ProteinModelPortal:   P58118
- GeneID:   1115755
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0333
- NMPDR:   fig|272623.1.peg.2133
- HOGENOM:   HBG565931
- OMA:   IQTYVIS
- ProtClustDB:   PRK09204
- BioCyc:   LLAC272623:L0333-MONOMER
- InterPro:   IPR002208
- InterPro:   IPR023201
- PANTHER:   PTHR10906
- PIRSF:   PIRSF004557
- PRINTS:   PR00303
- TIGRFAMs:   TIGR00967

Pfam domain/function: PF00344 SecY; SSF103491 SecY

EC number: NA

Molecular weight: Translated: 48456; Mature: 48456

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS00755 SECY_1; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf660180)-; HASH(0xde05574)-; HASH(0xfcf9a9c)-; HASH(0xfb01ca4)-; HASH(0xd1eb4f0)-; HASH(0xf676238)-; HASH(0xf050970)-; HASH(0xf4ff0bc)-; HASH(0xf6a5644)-; HASH(0x1006630c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCCCCCCH
>Mature Secondary Structure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HHHHHHHHCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471