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The map label for this gene is infA

Identifier: 15674054

GI number: 15674054

Start: 2154030

End: 2154248

Strand: Reverse

Name: infA

Synonym: L0366

Alternate gene names: 15674054

Gene position: 2154248-2154030 (Counterclockwise)

Preceding gene: 15674055

Following gene: 15674053

Centisome position: 91.07

GC content: 42.01

Gene sequence:

>219_bases
TTGGCAAAAGATGATGTAATTGAAGTAGACGGCAAAGTCGTTGACACCATGCCGAATGCGATGTTCACGGTTGAACTCGA
AAATGGTCACCAAGTCTTGGCGACGATTTCAGGAAAAATTCGAAAGAATTATATCCGTATCTTGCCTGGAGACAAGGTTC
AAGTTGAACTCTCACCATACGATTTGACACGCGGACGAATTACTTACCGATTTAAGTAA

Upstream 100 bases:

>100_bases
ACTTGCATTTGTTGCTGAAAAATGCTAAAATAAACAAGTCCGACTTTTTAGATATATATAGTATATATCTTTCGGGAAAT
TTCTAAGGAGGTACTTTTGC

Downstream 100 bases:

>100_bases
TCCGGACATTCATTGAGTGCATGATGCACAGTAACCATAGAAAGGAAGACACAATGAAAGTAAGACCATCAGTTAAACCA
ATCTGCGAATACTGTAAAGT

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 72; Mature: 71

Protein sequence:

>72_residues
MAKDDVIEVDGKVVDTMPNAMFTVELENGHQVLATISGKIRKNYIRILPGDKVQVELSPYDLTRGRITYRFK

Sequences:

>Translated_72_residues
MAKDDVIEVDGKVVDTMPNAMFTVELENGHQVLATISGKIRKNYIRILPGDKVQVELSPYDLTRGRITYRFK
>Mature_71_residues
AKDDVIEVDGKVVDTMPNAMFTVELENGHQVLATISGKIRKNYIRILPGDKVQVELSPYDLTRGRITYRFK

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=72, Percent_Identity=68.0555555555556, Blast_Score=105, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_LACLA (P0A3K4)

Other databases:

- EMBL:   AE005176
- PIR:   H86883
- RefSeq:   NP_268229.1
- ProteinModelPortal:   P0A3K4
- SMR:   P0A3K4
- GeneID:   1115749
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0366
- NMPDR:   fig|272623.1.peg.2127
- HOGENOM:   HBG286099
- OMA:   KMRMHFI
- ProtClustDB:   PRK00276
- BioCyc:   LLAC272623:L0366-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 8196; Mature: 8064

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDDVIEVDGKVVDTMPNAMFTVELENGHQVLATISGKIRKNYIRILPGDKVQVELSPY
CCCCCEEEECCEEEECCCCEEEEEEECCCCEEEEEECCCEEEEEEEECCCCEEEEEECCC
DLTRGRITYRFK
CCCCCEEEEEEC
>Mature Secondary Structure 
AKDDVIEVDGKVVDTMPNAMFTVELENGHQVLATISGKIRKNYIRILPGDKVQVELSPY
CCCCEEEECCEEEECCCCEEEEEEECCCCEEEEEECCCEEEEEEEECCCCEEEEEECCC
DLTRGRITYRFK
CCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471