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The map label for this gene is galE

Identifier: 15673961

GI number: 15673961

Start: 2054147

End: 2055127

Strand: Reverse

Name: galE

Synonym: L0024

Alternate gene names: 15673961

Gene position: 2055127-2054147 (Counterclockwise)

Preceding gene: 30024070

Following gene: 15673960

Centisome position: 86.88

GC content: 38.23

Gene sequence:

>981_bases
ATGACGGTTTTAGTTCTTGGTGGAGCAGGATACGTGGGAAGTCACGCGGTAGATATGCTTCTTAAACGTGGTTACGATGT
GGCAGTGGTGGATAATTTAGTGACAGGCCACCGTGAATCTGTTCCAGCAAATGTACGCTTTTACGAGGGTGATGTACGTG
ATCAAGCTTTCTTAGCAGATGTTTTTGAAAAAGAAAATATTGAAGGAATCATGCACTTTTGTGCTTACTCTTTAGTGGGT
GAGTCAATGCAAAAACCTTTAATGTATTTTAATAATAATGTTGGTGGTGCTCAAGTAATTCTAGAAACGATGGAAGAATT
CGGAGTAAAACATATTGTTTTTTCAAGTACAGCAGCTACATTTGGAATTCCAGAAAAAAGTCCAATTTCAGAAAAAACAC
CTCAAAAACCAATTAATCCTTATGGTGAAAGCAAATTAATCATGGAAAAAATGATGAAATGGCAATCGCAAGCAACTGAT
ATGACTTATGTCGCTTTACGTTATTTCAATGTTGCAGGGGCTAAGGATGATGGTTCAATTGGTGAAGCTCATAAAAATGA
AACACATTTGATTCCAATTATTTTGCAAACTGCACTTGGTCAAAGAGAGTTCATTACTATTTATGGTGATGACTATCACA
CGCCTGATGGAACTTGTATTCGTGATTATATTGATATGGAAGATTTGATTGAAGCACACATCAAAGCACTAGAGTATCTT
AAAGCGGGCGGTCAGTCTGACCAATTTAATCTCGGTTCAAGTAAGGGTTATTCAAATCTTGAAGTGCTTGAAACCGCACG
AAAAGTAACAGGTAAAGAAATTCCAAGCCAAATGGGTGAACGCCGTGCAGGAGACCCAGATGAGCTGGTTGCTGATTCAA
CAAAAGCTGGTGAAATTTTGGGTTGGAAAGCACAAAATGATTTAGAGCACATTATTACGAACGCTTGGAAATGGCACCAA
AGTCATCCAAAAGGTTACTAG

Upstream 100 bases:

>100_bases
ATTGACAAAGGGAAATTATCATTATGAAGTTAGTTTTAAATTAACGTGATGATCCAAATTTTCAAGAATTTGATATAATA
TAGAGAAAATGGAGGTTCTT

Downstream 100 bases:

>100_bases
TTAATTATCTAAAATTCGAAAAAAAAAGCTCAAATTTTTGAGCTTTTTTTGTATGTAATCGTCATGAAAATGTAATGGTA
ATTGTGATAATTATTATTAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTVLVLGGAGYVGSHAVDMLLKRGYDVAVVDNLVTGHRESVPANVRFYEGDVRDQAFLADVFEKENIEGIMHFCAYSLVG
ESMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAATFGIPEKSPISEKTPQKPINPYGESKLIMEKMMKWQSQATD
MTYVALRYFNVAGAKDDGSIGEAHKNETHLIPIILQTALGQREFITIYGDDYHTPDGTCIRDYIDMEDLIEAHIKALEYL
KAGGQSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRAGDPDELVADSTKAGEILGWKAQNDLEHIITNAWKWHQ
SHPKGY

Sequences:

>Translated_326_residues
MTVLVLGGAGYVGSHAVDMLLKRGYDVAVVDNLVTGHRESVPANVRFYEGDVRDQAFLADVFEKENIEGIMHFCAYSLVG
ESMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAATFGIPEKSPISEKTPQKPINPYGESKLIMEKMMKWQSQATD
MTYVALRYFNVAGAKDDGSIGEAHKNETHLIPIILQTALGQREFITIYGDDYHTPDGTCIRDYIDMEDLIEAHIKALEYL
KAGGQSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRAGDPDELVADSTKAGEILGWKAQNDLEHIITNAWKWHQ
SHPKGY
>Mature_325_residues
TVLVLGGAGYVGSHAVDMLLKRGYDVAVVDNLVTGHRESVPANVRFYEGDVRDQAFLADVFEKENIEGIMHFCAYSLVGE
SMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAATFGIPEKSPISEKTPQKPINPYGESKLIMEKMMKWQSQATDM
TYVALRYFNVAGAKDDGSIGEAHKNETHLIPIILQTALGQREFITIYGDDYHTPDGTCIRDYIDMEDLIEAHIKALEYLK
AGGQSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRAGDPDELVADSTKAGEILGWKAQNDLEHIITNAWKWHQS
HPKGY

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=40.4692082111437, Blast_Score=244, Evalue=9e-65,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=40.4692082111437, Blast_Score=244, Evalue=9e-65,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=40.4692082111437, Blast_Score=244, Evalue=9e-65,
Organism=Homo sapiens, GI42516563, Length=320, Percent_Identity=27.5, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI7657641, Length=260, Percent_Identity=25.7692307692308, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI193211614, Length=242, Percent_Identity=29.3388429752066, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI8393516, Length=242, Percent_Identity=29.3388429752066, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=38.0952380952381, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1788353, Length=363, Percent_Identity=26.9972451790634, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI48994969, Length=354, Percent_Identity=25.4237288135593, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790049, Length=262, Percent_Identity=28.2442748091603, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=37.6811594202899, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=37.463976945245, Blast_Score=237, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17568069, Length=330, Percent_Identity=25.1515151515152, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17539532, Length=314, Percent_Identity=25.1592356687898, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=39.766081871345, Blast_Score=243, Evalue=4e-65,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=38.1924198250729, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI21356223, Length=319, Percent_Identity=26.3322884012539, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36230; Mature: 36099

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLVLGGAGYVGSHAVDMLLKRGYDVAVVDNLVTGHRESVPANVRFYEGDVRDQAFLAD
CEEEEEECCCCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCEEEEECCCCHHHHHHH
VFEKENIEGIMHFCAYSLVGESMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAAT
HHHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCHHC
FGIPEKSPISEKTPQKPINPYGESKLIMEKMMKWQSQATDMTYVALRYFNVAGAKDDGSI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCC
GEAHKNETHLIPIILQTALGQREFITIYGDDYHTPDGTCIRDYIDMEDLIEAHIKALEYL
CCCCCCCCEEHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
KAGGQSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRAGDPDELVADSTKAGEIL
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEE
GWKAQNDLEHIITNAWKWHQSHPKGY
ECCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVLVLGGAGYVGSHAVDMLLKRGYDVAVVDNLVTGHRESVPANVRFYEGDVRDQAFLAD
EEEEEECCCCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCEEEEECCCCHHHHHHH
VFEKENIEGIMHFCAYSLVGESMQKPLMYFNNNVGGAQVILETMEEFGVKHIVFSSTAAT
HHHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCHHC
FGIPEKSPISEKTPQKPINPYGESKLIMEKMMKWQSQATDMTYVALRYFNVAGAKDDGSI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCC
GEAHKNETHLIPIILQTALGQREFITIYGDDYHTPDGTCIRDYIDMEDLIEAHIKALEYL
CCCCCCCCEEHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
KAGGQSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGERRAGDPDELVADSTKAGEIL
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEE
GWKAQNDLEHIITNAWKWHQSHPKGY
ECCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]