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The map label for this gene is yuaD

Identifier: 15673908

GI number: 15673908

Start: 2004383

End: 2005306

Strand: Reverse

Name: yuaD

Synonym: L187815

Alternate gene names: 15673908

Gene position: 2005306-2004383 (Counterclockwise)

Preceding gene: 30024062

Following gene: 15673907

Centisome position: 84.77

GC content: 35.93

Gene sequence:

>924_bases
ATGATAAAAAATGGACGTATTGTCAAATCTTTGGCAGGCTTTTATGATGTAGAATCAGAAGGTGAAGTTTATCAGACGCG
TGCGCGTGGTAATTTCAGAAAAAAAGGAATGAAACCTGTTGTGGGAGATTTTGTTGAATTTTCTACTGAGGAAAATTCAG
AAGGTTATATTTTAAAAATTGGTGAGCGAAAAAATTCTTTAATTCGACCATCTATTGCTAATATTGATCAAGCTGTGATT
ATTATGTCAACAGTGAGCCCAAATTTTAGTTTGAATTTATTAGACCGCTTTTTGGTTTTTTTAGAGCATAAAAATATTCA
CCCGATGATTTACATTTCTAAGTTGGATTTACTGACAGAGATGCAGGAAGGCTCAGATAAGAATAAAAAAACTTTTAATC
AGCTGACAGATTATGAACAGATAAAAAGTGATTATGAACAAATTGGTTATGATGTTTTTTTTGATGCTGAGCATTTGGTC
AGTAATTTAGCGGGAAAAGTAACTGTCTTTATGGGGCAAACTGGCGCTGGTAAGACTACTTTGCTAAATAAAATTGCACC
AGAAATGCAACTGGCAACGGGAGAAACTTCAGAAAAACTGGGACGTGGGCGTCATACGACACGTCATGTTGAATTTTTTG
AATTGGCTGGTGGCTTAATTGCTGACACACCGGGATTTTCTAGTCTAGACTATGAAGTGACGAATCGGCCGGATTTAAAT
GCTGCTTTTCCTGAAATTTTAAGAATCAGTCATGATTGCAAGTTTCGCGAATGTACACATACGCATGAACCCAGCTGTGC
AGTCAAGCTGGCACTAGAAAATCATGAAATTTTAGAGAGCCGCTATGATAATTATTTACAGATTTTAGATGAAATTAATC
ACACGAGGGAGACTTATGAGAAAAAACGAAAAAAACAGGGCTAA

Upstream 100 bases:

>100_bases
CTTGGGGACGGAAAAATATTCAAATCACTGTTTTGAGTTAATAAACTTTAAAAAATAATGAAAGGCTTACAGTGAAGCCT
TTTTTTGGTATAATGAGAAC

Downstream 100 bases:

>100_bases
AGATAATATTTGGTTAAAACAAGCTAGTTTTTTTGCCCTTGTTTTAGCATGGATTTTAGCGATTTATTTTAAAAATGATT
TGTCAAAAACAATGATGATT

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MIKNGRIVKSLAGFYDVESEGEVYQTRARGNFRKKGMKPVVGDFVEFSTEENSEGYILKIGERKNSLIRPSIANIDQAVI
IMSTVSPNFSLNLLDRFLVFLEHKNIHPMIYISKLDLLTEMQEGSDKNKKTFNQLTDYEQIKSDYEQIGYDVFFDAEHLV
SNLAGKVTVFMGQTGAGKTTLLNKIAPEMQLATGETSEKLGRGRHTTRHVEFFELAGGLIADTPGFSSLDYEVTNRPDLN
AAFPEILRISHDCKFRECTHTHEPSCAVKLALENHEILESRYDNYLQILDEINHTRETYEKKRKKQG

Sequences:

>Translated_307_residues
MIKNGRIVKSLAGFYDVESEGEVYQTRARGNFRKKGMKPVVGDFVEFSTEENSEGYILKIGERKNSLIRPSIANIDQAVI
IMSTVSPNFSLNLLDRFLVFLEHKNIHPMIYISKLDLLTEMQEGSDKNKKTFNQLTDYEQIKSDYEQIGYDVFFDAEHLV
SNLAGKVTVFMGQTGAGKTTLLNKIAPEMQLATGETSEKLGRGRHTTRHVEFFELAGGLIADTPGFSSLDYEVTNRPDLN
AAFPEILRISHDCKFRECTHTHEPSCAVKLALENHEILESRYDNYLQILDEINHTRETYEKKRKKQG
>Mature_307_residues
MIKNGRIVKSLAGFYDVESEGEVYQTRARGNFRKKGMKPVVGDFVEFSTEENSEGYILKIGERKNSLIRPSIANIDQAVI
IMSTVSPNFSLNLLDRFLVFLEHKNIHPMIYISKLDLLTEMQEGSDKNKKTFNQLTDYEQIKSDYEQIGYDVFFDAEHLV
SNLAGKVTVFMGQTGAGKTTLLNKIAPEMQLATGETSEKLGRGRHTTRHVEFFELAGGLIADTPGFSSLDYEVTNRPDLN
AAFPEILRISHDCKFRECTHTHEPSCAVKLALENHEILESRYDNYLQILDEINHTRETYEKKRKKQG

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain

Homologues:

Organism=Escherichia coli, GI87082381, Length=316, Percent_Identity=30.379746835443, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSGA_LACLA (Q9CEB7)

Other databases:

- EMBL:   AE005176
- PIR:   F86865
- RefSeq:   NP_268083.1
- ProteinModelPortal:   Q9CEB7
- SMR:   Q9CEB7
- GeneID:   1115594
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L187815
- NMPDR:   fig|272623.1.peg.1973
- HOGENOM:   HBG652450
- OMA:   IAGFYDV
- ProtClustDB:   PRK00098
- BioCyc:   LLAC272623:L187815-MONOMER
- HAMAP:   MF_01820
- InterPro:   IPR010914
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004881
- Gene3D:   G3DSA:2.40.50.140
- TIGRFAMs:   TIGR00157

Pfam domain/function: PF03193 DUF258; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 34967; Mature: 34967

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNGRIVKSLAGFYDVESEGEVYQTRARGNFRKKGMKPVVGDFVEFSTEENSEGYILKI
CCCCCHHHHHHHHHHCCCCCCCEEEHHHCCCHHHCCCCCHHHHHHHHCCCCCCCCEEEEE
GERKNSLIRPSIANIDQAVIIMSTVSPNFSLNLLDRFLVFLEHKNIHPMIYISKLDLLTE
CCCCCCCCCCCHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHH
MQEGSDKNKKTFNQLTDYEQIKSDYEQIGYDVFFDAEHLVSNLAGKVTVFMGQTGAGKTT
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCEEEEEEECCCCCHHH
LLNKIAPEMQLATGETSEKLGRGRHTTRHVEFFELAGGLIADTPGFSSLDYEVTNRPDLN
HHHHHCCHHEECCCCCHHHHCCCCCCHHHHHHHHHCCCCEECCCCCCCCCEEECCCCCCC
AAFPEILRISHDCKFRECTHTHEPSCAVKLALENHEILESRYDNYLQILDEINHTRETYE
HHHHHHHHHCCCCCCHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
KKRKKQG
HHHHCCC
>Mature Secondary Structure
MIKNGRIVKSLAGFYDVESEGEVYQTRARGNFRKKGMKPVVGDFVEFSTEENSEGYILKI
CCCCCHHHHHHHHHHCCCCCCCEEEHHHCCCHHHCCCCCHHHHHHHHCCCCCCCCEEEEE
GERKNSLIRPSIANIDQAVIIMSTVSPNFSLNLLDRFLVFLEHKNIHPMIYISKLDLLTE
CCCCCCCCCCCHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHH
MQEGSDKNKKTFNQLTDYEQIKSDYEQIGYDVFFDAEHLVSNLAGKVTVFMGQTGAGKTT
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCEEEEEEECCCCCHHH
LLNKIAPEMQLATGETSEKLGRGRHTTRHVEFFELAGGLIADTPGFSSLDYEVTNRPDLN
HHHHHCCHHEECCCCCHHHHCCCCCCHHHHHHHHHCCCCEECCCCCCCCCEEECCCCCCC
AAFPEILRISHDCKFRECTHTHEPSCAVKLALENHEILESRYDNYLQILDEINHTRETYE
HHHHHHHHHCCCCCCHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
KKRKKQG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471