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The map label for this gene is acmB

Identifier: 15673889

GI number: 15673889

Start: 1975894

End: 1977321

Strand: Reverse

Name: acmB

Synonym: L159324

Alternate gene names: 15673889

Gene position: 1977321-1975894 (Counterclockwise)

Preceding gene: 15673890

Following gene: 15673888

Centisome position: 83.59

GC content: 36.48

Gene sequence:

>1428_bases
ATGACGACTTTTGGCGTGGCTGGCCATGCTGATGGAGTAACTGTTGGAAGTAGTTCAGATGCATCATCAAGCACAGGTAG
CTCAAGTTCATCATCAGGTACAGGGGGTTCAAGTTCATCATCAAGTACAGGTAGCTCAAGCTCATCATCAAATTCAAATG
CTTCAAGTTCATCGTCAAGTACAGGTAATTCAAGTTCATCATCAAAACCAAGTACTTCAGGTTCGACATCAAAACCAAGT
AATCCAAGTTCATCAACAAATAATAATTCAACTAGTAATTCCTCTACAACAACTCAAGCACCATCAACTTCAGTTTCTAC
CATAGCTCCTTCAGCATCAACTTCTACAGTTGCACCCTCTAATTATTCACAGGATAATGCCTACTATCAAACATCAACTG
CAGCACAAATTCCTAATTCTTCAGCAGATTCAGCTCCTTCTATTTACGCTGGCCCTGTTTTGAAAACAATTGAAGCAGCT
AAGTCAATTGATAAAATTGATACTTCTAGTACAGAAGCCTTTATTAAAAGTATTGCAGACCGCGTGAGAATTTTAGCTGG
TAAGAATAATTTGTATGCATCAATTATCTTGGCACAGGCGATTTTAGAATCTGGTTCTGGTCAAAGTAATATGAGTCAGC
AGTATTTTAATATTTTCAATATTACAGGTGCTTATTTAGGAAAATCAATTTCATTTAAGACGGAAGAATTTTCGGGAAAT
AATCCTTATTATATTGAACAAAGTTTTAGAGTTTATAGTAATTATGACCAAGCCTTGGATGATTATATTAATTTAATGAT
TAAAGGGACAACTTGGAACTCAGAAATTTATGCTGGCGCATGGAAGTCACATGCTAAGACTTACCAAGAGGCGGCTCAAG
CATTGCAAGGAATTTTTGCTACTGACCCAGCATATGCACAAAAATTAATTGAAATTATTCAAGAATATAAATTAGATGCT
TATGATAATGTTGATAGTACAACACAAGTTGTAGATAGTAAAATTCCTGAAAGTCCATTGGCGGCATCAAAATTAGATAA
TTCAGCTTATCCAGAATATAATGGGGTAGAATATCCAGGTGCTGATAGTTATGCTTTTGGTAATTGTACACAGTATGTTT
ATAACCGTATCATTCAATTAGGTGGGCTCGTTGGAACACATATGGGAAATGGTGGAGAATGGGGAATTAATGCCCAAGCT
CAAGGTTATTTCACAACAACTGTTCCAACTGAGGGTTATGCTGTTAGCTTCCCACCAGGAGTAGCTGGTTCAAGTTCAGA
ATATGGTCACGTAGCTTTTGTTGAAAAGGTTTATTCAGATAACTCTATTCTCGTTTCAGAGATGAATGTTAAAGGTAATA
ATATTGTCAGCGAACGCCATATTTCTGCTGGTGTAGCTGCTTTGGCAACTTATATTCAACCTAAATAA

Upstream 100 bases:

>100_bases
AATACATACCATGGAGGATTAACTAAAATTGACTAATAATGATAAAACTAAGCGCTTAAAAAAGGAAAAATTTATTGCGG
GAACAGCGCTGATTTTAGGA

Downstream 100 bases:

>100_bases
TTACTGACAAAATTAATTAGTGGTTCTGTCAGTAAAATAGGAGTATTGAATCTTTTATTTAGTTAAAAAAAGAAGATGTT
AAAAATCAGCCCAAAGGCTG

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: Autolysin; Lysozyme; Peptidoglycan hydrolase [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTTFGVAGHADGVTVGSSSDASSSTGSSSSSSGTGGSSSSSSTGSSSSSSNSNASSSSSSTGNSSSSSKPSTSGSTSKPS
NPSSSTNNNSTSNSSTTTQAPSTSVSTIAPSASTSTVAPSNYSQDNAYYQTSTAAQIPNSSADSAPSIYAGPVLKTIEAA
KSIDKIDTSSTEAFIKSIADRVRILAGKNNLYASIILAQAILESGSGQSNMSQQYFNIFNITGAYLGKSISFKTEEFSGN
NPYYIEQSFRVYSNYDQALDDYINLMIKGTTWNSEIYAGAWKSHAKTYQEAAQALQGIFATDPAYAQKLIEIIQEYKLDA
YDNVDSTTQVVDSKIPESPLAASKLDNSAYPEYNGVEYPGADSYAFGNCTQYVYNRIIQLGGLVGTHMGNGGEWGINAQA
QGYFTTTVPTEGYAVSFPPGVAGSSSEYGHVAFVEKVYSDNSILVSEMNVKGNNIVSERHISAGVAALATYIQPK

Sequences:

>Translated_475_residues
MTTFGVAGHADGVTVGSSSDASSSTGSSSSSSGTGGSSSSSSTGSSSSSSNSNASSSSSSTGNSSSSSKPSTSGSTSKPS
NPSSSTNNNSTSNSSTTTQAPSTSVSTIAPSASTSTVAPSNYSQDNAYYQTSTAAQIPNSSADSAPSIYAGPVLKTIEAA
KSIDKIDTSSTEAFIKSIADRVRILAGKNNLYASIILAQAILESGSGQSNMSQQYFNIFNITGAYLGKSISFKTEEFSGN
NPYYIEQSFRVYSNYDQALDDYINLMIKGTTWNSEIYAGAWKSHAKTYQEAAQALQGIFATDPAYAQKLIEIIQEYKLDA
YDNVDSTTQVVDSKIPESPLAASKLDNSAYPEYNGVEYPGADSYAFGNCTQYVYNRIIQLGGLVGTHMGNGGEWGINAQA
QGYFTTTVPTEGYAVSFPPGVAGSSSEYGHVAFVEKVYSDNSILVSEMNVKGNNIVSERHISAGVAALATYIQPK
>Mature_474_residues
TTFGVAGHADGVTVGSSSDASSSTGSSSSSSGTGGSSSSSSTGSSSSSSNSNASSSSSSTGNSSSSSKPSTSGSTSKPSN
PSSSTNNNSTSNSSTTTQAPSTSVSTIAPSASTSTVAPSNYSQDNAYYQTSTAAQIPNSSADSAPSIYAGPVLKTIEAAK
SIDKIDTSSTEAFIKSIADRVRILAGKNNLYASIILAQAILESGSGQSNMSQQYFNIFNITGAYLGKSISFKTEEFSGNN
PYYIEQSFRVYSNYDQALDDYINLMIKGTTWNSEIYAGAWKSHAKTYQEAAQALQGIFATDPAYAQKLIEIIQEYKLDAY
DNVDSTTQVVDSKIPESPLAASKLDNSAYPEYNGVEYPGADSYAFGNCTQYVYNRIIQLGGLVGTHMGNGGEWGINAQAQ
GYFTTTVPTEGYAVSFPPGVAGSSSEYGHVAFVEKVYSDNSILVSEMNVKGNNIVSERHISAGVAALATYIQPK

Specific function: Hydrolyzes the cell wall of L.lactis and M.lysodeikticus. Required for cell separation during growth [H]

COG id: COG1705

COG function: function code NU; Muramidase (flagellum-specific)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787321, Length=154, Percent_Identity=31.8181818181818, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013338
- InterPro:   IPR002901
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01832 Glucosaminidase; PF01476 LysM [H]

EC number: =3.2.1.17 [H]

Molecular weight: Translated: 49529; Mature: 49397

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50911 CHAP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFGVAGHADGVTVGSSSDASSSTGSSSSSSGTGGSSSSSSTGSSSSSSNSNASSSSSS
CCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TGNSSSSSKPSTSGSTSKPSNPSSSTNNNSTSNSSTTTQAPSTSVSTIAPSASTSTVAPS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCC
NYSQDNAYYQTSTAAQIPNSSADSAPSIYAGPVLKTIEAAKSIDKIDTSSTEAFIKSIAD
CCCCCCCEEECCCHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RVRILAGKNNLYASIILAQAILESGSGQSNMSQQYFNIFNITGAYLGKSISFKTEEFSGN
HHEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
NPYYIEQSFRVYSNYDQALDDYINLMIKGTTWNSEIYAGAWKSHAKTYQEAAQALQGIFA
CCEEEECCHHHHHHHHHHHHHHHEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHC
TDPAYAQKLIEIIQEYKLDAYDNVDSTTQVVDSKIPESPLAASKLDNSAYPEYNGVEYPG
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCC
ADSYAFGNCTQYVYNRIIQLGGLVGTHMGNGGEWGINAQAQGYFTTTVPTEGYAVSFPPG
CCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCC
VAGSSSEYGHVAFVEKVYSDNSILVSEMNVKGNNIVSERHISAGVAALATYIQPK
CCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTFGVAGHADGVTVGSSSDASSSTGSSSSSSGTGGSSSSSSTGSSSSSSNSNASSSSSS
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TGNSSSSSKPSTSGSTSKPSNPSSSTNNNSTSNSSTTTQAPSTSVSTIAPSASTSTVAPS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCC
NYSQDNAYYQTSTAAQIPNSSADSAPSIYAGPVLKTIEAAKSIDKIDTSSTEAFIKSIAD
CCCCCCCEEECCCHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RVRILAGKNNLYASIILAQAILESGSGQSNMSQQYFNIFNITGAYLGKSISFKTEEFSGN
HHEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
NPYYIEQSFRVYSNYDQALDDYINLMIKGTTWNSEIYAGAWKSHAKTYQEAAQALQGIFA
CCEEEECCHHHHHHHHHHHHHHHEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHC
TDPAYAQKLIEIIQEYKLDAYDNVDSTTQVVDSKIPESPLAASKLDNSAYPEYNGVEYPG
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCC
ADSYAFGNCTQYVYNRIIQLGGLVGTHMGNGGEWGINAQAQGYFTTTVPTEGYAVSFPPG
CCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCC
VAGSSSEYGHVAFVEKVYSDNSILVSEMNVKGNNIVSERHISAGVAALATYIQPK
CCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11131071 [H]