BacMap

Definition	Lactococcus lactis subsp. lactis Il1403, complete genome.
Accession	NC_002662
Length	2,365,589

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The map label for this gene is fabG2

Identifier: 15673768

GI number: 15673768

Start: 1844382

End: 1845128

Strand: Direct

Name: fabG2

Synonym: L27694

Alternate gene names: 15673768

Gene position: 1844382-1845128 (Clockwise)

Preceding gene: 15673767

Following gene: 15673769

Centisome position: 77.97

GC content: 35.61

Gene sequence:

>747_bases
ATGAACAAACGAACAATTTTGATTACCGGTGCAACAAGGGGAATCGGCTGGGCAATTGCTCAGAAAGCTGCTCAAGCCAA
TCACAAAGTCATTTTAACTGGCCGTGACCCACTTAGTTTAAAAAGTAGAGCTGAAGAATTGAAAAAAAAATTTCCCAAAA
CAGAAATCCAAGCTATTCCACTAGATGTTTCTAATCGCTCTAGCGTTGCTAATGCAGCCAAATTAATAAAGGATATTGAT
ATTCTAATTAATAATGCTGGAATTACTGCTGATAGTACTTTTAAGAAAATGAGCCCAGAAATTTGGGATGAAGTCATTTC
TGTCAATTTGACTGGTGTATTTAATAGTACTCACGCTTTGCTTGATAAAATCAATCAAGGTGGACAAATCATTACACTAA
CTTCAAAATCAGCTTTATTTGGTAACTTTGGGCAAGCAAACTACGCGGCGTCCAAAGCCGGCATCATTGCTTTTACGAAA
ACACTAGCTAAAGAATTGCAAAAAAGTATGATACGAGTAAATTCTGTTTCTCCTGCTGCCGTAACTGATATGACTCTACC
AGTATTAAAAAGTTTAAAAGAAACTTATGGTCAGAATATCCCTGATGAATGGAAAATGGGTTCAAGCTCTGATGTCGCTA
ATTTTATTATTAATGATTTAATTGAAAGCGAAATGACAGGCAAAATTTTTTCCATTAACGGCTCTGAGATTGGCTATTGG
CAAGAACCTACATTTCATAAACTTTAA

Upstream 100 bases:

>100_bases
CAGCCTATTTGAATGAACGCTTTTGTTTTATATTTAATCAAAACGCTTTTCAAATTACTGACAGAAATCAAACATTAATC
CTAAAAGGAGAATGGAAGCA

Downstream 100 bases:

>100_bases
TAAGGTATAGAAAGAGAATTAAATGACTTGGTATCACGAATTAGGAATAAAATATCCTCTTTTTCAAGGTGGAATGGCTT
GGGCTTCTAATGCTGAATTA

Product: 3-oxoacyl-acyl carrier protein reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNKRTILITGATRGIGWAIAQKAAQANHKVILTGRDPLSLKSRAEELKKKFPKTEIQAIPLDVSNRSSVANAAKLIKDID
ILINNAGITADSTFKKMSPEIWDEVISVNLTGVFNSTHALLDKINQGGQIITLTSKSALFGNFGQANYAASKAGIIAFTK
TLAKELQKSMIRVNSVSPAAVTDMTLPVLKSLKETYGQNIPDEWKMGSSSDVANFIINDLIESEMTGKIFSINGSEIGYW
QEPTFHKL

Sequences:

>Translated_248_residues
MNKRTILITGATRGIGWAIAQKAAQANHKVILTGRDPLSLKSRAEELKKKFPKTEIQAIPLDVSNRSSVANAAKLIKDID
ILINNAGITADSTFKKMSPEIWDEVISVNLTGVFNSTHALLDKINQGGQIITLTSKSALFGNFGQANYAASKAGIIAFTK
TLAKELQKSMIRVNSVSPAAVTDMTLPVLKSLKETYGQNIPDEWKMGSSSDVANFIINDLIESEMTGKIFSINGSEIGYW
QEPTFHKL
>Mature_248_residues
MNKRTILITGATRGIGWAIAQKAAQANHKVILTGRDPLSLKSRAEELKKKFPKTEIQAIPLDVSNRSSVANAAKLIKDID
ILINNAGITADSTFKKMSPEIWDEVISVNLTGVFNSTHALLDKINQGGQIITLTSKSALFGNFGQANYAASKAGIIAFTK
TLAKELQKSMIRVNSVSPAAVTDMTLPVLKSLKETYGQNIPDEWKMGSSSDVANFIINDLIESEMTGKIFSINGSEIGYW
QEPTFHKL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=219, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=31.25, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI15277342, Length=241, Percent_Identity=34.0248962655602, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI31542939, Length=262, Percent_Identity=27.4809160305344, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=28.1746031746032, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19923817, Length=195, Percent_Identity=30.2564102564103, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32483357, Length=180, Percent_Identity=29.4444444444444, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI83715985, Length=252, Percent_Identity=26.984126984127, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=204, Percent_Identity=28.4313725490196, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI7705925, Length=181, Percent_Identity=27.0718232044199, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI142976729, Length=183, Percent_Identity=30.6010928961749, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=28.4883720930233, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5031737, Length=231, Percent_Identity=27.7056277056277, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=28.9340101522843, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI157739938, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI7657478, Length=185, Percent_Identity=29.7297297297297, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI225579078, Length=194, Percent_Identity=28.3505154639175, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI66933014, Length=192, Percent_Identity=26.5625, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=33.8912133891213, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082100, Length=188, Percent_Identity=36.1702127659575, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790717, Length=191, Percent_Identity=30.8900523560209, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=28.2945736434109, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=32.7868852459016, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787526, Length=194, Percent_Identity=31.9587628865979, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI87082160, Length=195, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789208, Length=188, Percent_Identity=26.5957446808511, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788459, Length=220, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367175, Length=192, Percent_Identity=30.7291666666667, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=37.5510204081633, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=32.6530612244898, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17568967, Length=244, Percent_Identity=30.7377049180328, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=238, Percent_Identity=29.8319327731092, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=234, Percent_Identity=31.6239316239316, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=241, Percent_Identity=29.4605809128631, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=183, Percent_Identity=28.9617486338798, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71997402, Length=174, Percent_Identity=29.8850574712644, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=183, Percent_Identity=28.9617486338798, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=190, Percent_Identity=28.4210526315789, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=188, Percent_Identity=30.3191489361702, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=203, Percent_Identity=29.064039408867, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=28.1632653061224, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=27.6264591439689, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=239, Percent_Identity=29.2887029288703, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=189, Percent_Identity=31.2169312169312, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=193, Percent_Identity=32.6424870466321, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86565303, Length=201, Percent_Identity=27.8606965174129, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=28.6852589641434, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=191, Percent_Identity=30.8900523560209, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=27.843137254902, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=195, Percent_Identity=30.2564102564103, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=188, Percent_Identity=30.3191489361702, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=206, Percent_Identity=27.6699029126214, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=247, Percent_Identity=28.7449392712551, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=174, Percent_Identity=28.735632183908, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=205, Percent_Identity=36.0975609756098, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323882, Length=229, Percent_Identity=31.0043668122271, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324126, Length=238, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639444, Length=223, Percent_Identity=35.8744394618834, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24643142, Length=180, Percent_Identity=34.4444444444444, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859837, Length=201, Percent_Identity=31.3432835820896, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=29.9595141700405, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI221331218, Length=252, Percent_Identity=30.1587301587302, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24665243, Length=252, Percent_Identity=30.1587301587302, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17737361, Length=248, Percent_Identity=29.0322580645161, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI221331216, Length=251, Percent_Identity=30.6772908366534, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24665247, Length=251, Percent_Identity=30.6772908366534, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356301, Length=185, Percent_Identity=29.1891891891892, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644339, Length=179, Percent_Identity=31.2849162011173, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21358495, Length=245, Percent_Identity=28.9795918367347, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357041, Length=183, Percent_Identity=30.0546448087432, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28571526, Length=189, Percent_Identity=31.2169312169312, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007236, Length=233, Percent_Identity=27.8969957081545, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26995; Mature: 26995

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRTILITGATRGIGWAIAQKAAQANHKVILTGRDPLSLKSRAEELKKKFPKTEIQAIP
CCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEE
LDVSNRSSVANAAKLIKDIDILINNAGITADSTFKKMSPEIWDEVISVNLTGVFNSTHAL
CCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHCCHHHHHHHHHEEEEEEECHHHHH
LDKINQGGQIITLTSKSALFGNFGQANYAASKAGIIAFTKTLAKELQKSMIRVNSVSPAA
HHHHCCCCEEEEEECCCHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHH
VTDMTLPVLKSLKETYGQNIPDEWKMGSSSDVANFIINDLIESEMTGKIFSINGSEIGYW
HHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
QEPTFHKL
CCCCCCCC
>Mature Secondary Structure
MNKRTILITGATRGIGWAIAQKAAQANHKVILTGRDPLSLKSRAEELKKKFPKTEIQAIP
CCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEE
LDVSNRSSVANAAKLIKDIDILINNAGITADSTFKKMSPEIWDEVISVNLTGVFNSTHAL
CCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHCCHHHHHHHHHEEEEEEECHHHHH
LDKINQGGQIITLTSKSALFGNFGQANYAASKAGIIAFTKTLAKELQKSMIRVNSVSPAA
HHHHCCCCEEEEEECCCHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHH
VTDMTLPVLKSLKETYGQNIPDEWKMGSSSDVANFIINDLIESEMTGKIFSINGSEIGYW
HHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
QEPTFHKL
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]