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The map label for this gene is holA

Identifier: 15673636

GI number: 15673636

Start: 1702742

End: 1703746

Strand: Reverse

Name: holA

Synonym: L102491

Alternate gene names: 15673636

Gene position: 1703746-1702742 (Counterclockwise)

Preceding gene: 15673637

Following gene: 15673635

Centisome position: 72.02

GC content: 32.14

Gene sequence:

>1005_bases
ATGACAGTATTTGATGAATTTAATGAAATCAAAAGAAAAGGGCTCCCTCAAATTTTAGTAATTTTTGGTGAGTCAAGGGA
ACTAGTTGGAGAATTGAAAAATCAACTCTTAACAGAGGTTAATTTCGAGCCAACGGATTTGAGCCAGGCTTATTATGACT
TAACTCCTAGTAATAGCGATTTAGCCCTTGAAGATTTGGAATCTCTCCCTTTTTTCTCAGATTCTCGGTTGGTAATCCTG
GAAAACTTGGTTAATTTAACAACGGCTAAAAAAAGTGTTTTAGATGAAAAACAGTTGAAGCGCTTTGAAAATTTTTTAGA
TGATCCGCCGGAAACTACGCAACTTGTTTTAATCCTTTATGGAAAATTGGACAGTCGTCTTAAAGTTGTTAAAAAATTAA
AAGCTAAAGCAACTTTACTTGAAGCACAAGAATTAAAGAGTCAAGAATTAATTCAATATTTTAGTCGAATAAGTCCTTTA
CCAAAGGTAGTTTTGAGTTTAATTGCCGCTAAATCAAATGATAATTTTTCAGTAATGAAGCAAAATATTGACCTCGTTCA
AACTTATGCACTAGGGCGAGAAGTGACACTTGATGATGTGGAAAAAGTCGTCCCAAAATCGCTACAAGATAATATTTTTG
CCTTAACTGATTTAATTTTTAAAGGAAAAATTGATGAGGCGCGTGATTTAGTCCATGATTTGACCTTGCAAGGGGAAGAT
TTAATTAAAATATTAGCTATTTTGACAAATTCTTATCGTTTGTATTTACAAGTCAAACTTTTCCAAGCCAAGGGTTGGCA
AGAAAATCAACAAGTTGCCTTTTTAAAAATGCACCCTTATCCTGTAAAATTGGCCAATCAATTGGTTAGAAAATTAAACG
TTAAATCCTTAAAAAATGGACTTTCTGATTTAATTAAACTTGATTTTGATATAAAAACAAGTGCAGCTGATAAATCCTAT
CTTTTTGATATCACTTTAATCAGGTTGACCTTGAAAAAAAACTGA

Upstream 100 bases:

>100_bases
TGCTAAACTCTTTCAAGTTGGTTGTTTAGGTTTTGCTCTGCTCATCCTGCTCCTTGTTCTCTTGGGGTTTGCTTTAAAAA
TGGTAACGAGGTAGTTAAAA

Downstream 100 bases:

>100_bases
AAATCTGTTATCATAAATAATGGACATTTTATAATGATGATGAAGAGGTAAAAATGCCGACATTTAAATTTACGCCTAAA
GATATCTATGAAGCAGACTT

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTVFDEFNEIKRKGLPQILVIFGESRELVGELKNQLLTEVNFEPTDLSQAYYDLTPSNSDLALEDLESLPFFSDSRLVIL
ENLVNLTTAKKSVLDEKQLKRFENFLDDPPETTQLVLILYGKLDSRLKVVKKLKAKATLLEAQELKSQELIQYFSRISPL
PKVVLSLIAAKSNDNFSVMKQNIDLVQTYALGREVTLDDVEKVVPKSLQDNIFALTDLIFKGKIDEARDLVHDLTLQGED
LIKILAILTNSYRLYLQVKLFQAKGWQENQQVAFLKMHPYPVKLANQLVRKLNVKSLKNGLSDLIKLDFDIKTSAADKSY
LFDITLIRLTLKKN

Sequences:

>Translated_334_residues
MTVFDEFNEIKRKGLPQILVIFGESRELVGELKNQLLTEVNFEPTDLSQAYYDLTPSNSDLALEDLESLPFFSDSRLVIL
ENLVNLTTAKKSVLDEKQLKRFENFLDDPPETTQLVLILYGKLDSRLKVVKKLKAKATLLEAQELKSQELIQYFSRISPL
PKVVLSLIAAKSNDNFSVMKQNIDLVQTYALGREVTLDDVEKVVPKSLQDNIFALTDLIFKGKIDEARDLVHDLTLQGED
LIKILAILTNSYRLYLQVKLFQAKGWQENQQVAFLKMHPYPVKLANQLVRKLNVKSLKNGLSDLIKLDFDIKTSAADKSY
LFDITLIRLTLKKN
>Mature_333_residues
TVFDEFNEIKRKGLPQILVIFGESRELVGELKNQLLTEVNFEPTDLSQAYYDLTPSNSDLALEDLESLPFFSDSRLVILE
NLVNLTTAKKSVLDEKQLKRFENFLDDPPETTQLVLILYGKLDSRLKVVKKLKAKATLLEAQELKSQELIQYFSRISPLP
KVVLSLIAAKSNDNFSVMKQNIDLVQTYALGREVTLDDVEKVVPKSLQDNIFALTDLIFKGKIDEARDLVHDLTLQGEDL
IKILAILTNSYRLYLQVKLFQAKGWQENQQVAFLKMHPYPVKLANQLVRKLNVKSLKNGLSDLIKLDFDIKTSAADKSYL
FDITLIRLTLKKN

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 38150; Mature: 38019

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFDEFNEIKRKGLPQILVIFGESRELVGELKNQLLTEVNFEPTDLSQAYYDLTPSNSD
CCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHEECCCCCCC
LALEDLESLPFFSDSRLVILENLVNLTTAKKSVLDEKQLKRFENFLDDPPETTQLVLILY
CHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
GKLDSRLKVVKKLKAKATLLEAQELKSQELIQYFSRISPLPKVVLSLIAAKSNDNFSVMK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHH
QNIDLVQTYALGREVTLDDVEKVVPKSLQDNIFALTDLIFKGKIDEARDLVHDLTLQGED
HCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHH
LIKILAILTNSYRLYLQVKLFQAKGWQENQQVAFLKMHPYPVKLANQLVRKLNVKSLKNG
HHHHHHHHHCCEEEEEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHCHHHHHHH
LSDLIKLDFDIKTSAADKSYLFDITLIRLTLKKN
HHHHHHHCCCCCCCCCCCHHEEEEEEEEEEEECC
>Mature Secondary Structure 
TVFDEFNEIKRKGLPQILVIFGESRELVGELKNQLLTEVNFEPTDLSQAYYDLTPSNSD
CCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHEECCCCCCC
LALEDLESLPFFSDSRLVILENLVNLTTAKKSVLDEKQLKRFENFLDDPPETTQLVLILY
CHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
GKLDSRLKVVKKLKAKATLLEAQELKSQELIQYFSRISPLPKVVLSLIAAKSNDNFSVMK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHH
QNIDLVQTYALGREVTLDDVEKVVPKSLQDNIFALTDLIFKGKIDEARDLVHDLTLQGED
HCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHH
LIKILAILTNSYRLYLQVKLFQAKGWQENQQVAFLKMHPYPVKLANQLVRKLNVKSLKNG
HHHHHHHHHCCEEEEEEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHCHHHHHHH
LSDLIKLDFDIKTSAADKSYLFDITLIRLTLKKN
HHHHHHHCCCCCCCCCCCHHEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]