Click here to switch to the map view.

The map label for this gene is llrB

Identifier: 15673417

GI number: 15673417

Start: 1458173

End: 1458883

Strand: Direct

Name: llrB

Synonym: L0123

Alternate gene names: 15673417

Gene position: 1458173-1458883 (Clockwise)

Preceding gene: 15673415

Following gene: 15673418

Centisome position: 61.64

GC content: 33.61

Gene sequence:

>711_bases
ATGAAAAAAATTTTAATTGCTGATGATGATCGGGCAATTTTGACCCTTTTATCTTATAATTTTCGGCAAAATGATTACGA
AGTAACTATTGTATCAGACGGGAAAAAAGCTTATGACAAAGCTCGTAAAAATCCCTTTGATTTACTTCTACTTGATTTAA
TGATGCCCGAATATTCCGGAATTGAAGTCACCCAAAAACTTCGTAAAGAAGATAATTTTACACCAATTTTAATTTTAACT
GCTCGAGATGATGATGAAATGAAACTGACAGGGCTGTCAGCAGGTTCTGATGAGTATTTAGATAAAACGACTCCAATGAA
AGAAATCATTGTCAGAGCCGATGCGCTCATTCGCAGAAATCAAATGTATAACCAAGCACCATCCGAAACTGTCAGTGAAG
CTTTAGATGAAAGACCTTCATCATTAGTTACTGACAGATTGGTCATTGATTTTATAAAAAAAGAAGTCACTTTTGACGAA
AAAGTTTTAGATTTAACCAAACGAGAATTTGAAATCCTTGAACTCTTAGCTAAAAGAGAGGGAAAAATTGTCAGTCGTGA
AGAACTCCTGCAACATTTTTGGGGAATTTCAGACACTGCTGAAACCCGCACCATTGATGTGCTCATTTCTAAAATTCGTA
AAAAATTAAATAATCATTATATCAAAACAAAACGAGGATTCGGATACTATTTTGAAGAAAATGAAACTTAA

Upstream 100 bases:

>100_bases
TTTTTTTATCTTTATCAAAGTCTAAGTATCCATTATTTTTTTAGCTAAAAATAATAATTTATTCTATACAAAACTCCCTG
TTTTCGTTATAATTAAAAGT

Downstream 100 bases:

>100_bases
ACACATCATGCTTATGACGGTCCTATATATTATTGCGACCTTAAGTCTGGTGATTCTATCGAACCAAAATATCTTAGAAA
ATGATACAAATCGAGTATTA

Product: two-component system regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKKILIADDDRAILTLLSYNFRQNDYEVTIVSDGKKAYDKARKNPFDLLLLDLMMPEYSGIEVTQKLRKEDNFTPILILT
ARDDDEMKLTGLSAGSDEYLDKTTPMKEIIVRADALIRRNQMYNQAPSETVSEALDERPSSLVTDRLVIDFIKKEVTFDE
KVLDLTKREFEILELLAKREGKIVSREELLQHFWGISDTAETRTIDVLISKIRKKLNNHYIKTKRGFGYYFEENET

Sequences:

>Translated_236_residues
MKKILIADDDRAILTLLSYNFRQNDYEVTIVSDGKKAYDKARKNPFDLLLLDLMMPEYSGIEVTQKLRKEDNFTPILILT
ARDDDEMKLTGLSAGSDEYLDKTTPMKEIIVRADALIRRNQMYNQAPSETVSEALDERPSSLVTDRLVIDFIKKEVTFDE
KVLDLTKREFEILELLAKREGKIVSREELLQHFWGISDTAETRTIDVLISKIRKKLNNHYIKTKRGFGYYFEENET
>Mature_236_residues
MKKILIADDDRAILTLLSYNFRQNDYEVTIVSDGKKAYDKARKNPFDLLLLDLMMPEYSGIEVTQKLRKEDNFTPILILT
ARDDDEMKLTGLSAGSDEYLDKTTPMKEIIVRADALIRRNQMYNQAPSETVSEALDERPSSLVTDRLVIDFIKKEVTFDE
KVLDLTKREFEILELLAKREGKIVSREELLQHFWGISDTAETRTIDVLISKIRKKLNNHYIKTKRGFGYYFEENET

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=233, Percent_Identity=31.3304721030043, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=37.1794871794872, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788394, Length=239, Percent_Identity=30.9623430962343, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786599, Length=236, Percent_Identity=30.5084745762712, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787375, Length=234, Percent_Identity=30.3418803418803, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786784, Length=234, Percent_Identity=28.2051282051282, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=31.3304721030043, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=27.7777777777778, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=29.004329004329, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=27.7056277056277, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI145693140, Length=244, Percent_Identity=32.7868852459016, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1786911, Length=238, Percent_Identity=27.3109243697479, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=29.2372881355932, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790437, Length=99, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27483; Mature: 27483

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILIADDDRAILTLLSYNFRQNDYEVTIVSDGKKAYDKARKNPFDLLLLDLMMPEYSG
CCEEEEECCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHCCCCCC
IEVTQKLRKEDNFTPILILTARDDDEMKLTGLSAGSDEYLDKTTPMKEIIVRADALIRRN
HHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHH
QMYNQAPSETVSEALDERPSSLVTDRLVIDFIKKEVTFDEKVLDLTKREFEILELLAKRE
HHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
GKIVSREELLQHFWGISDTAETRTIDVLISKIRKKLNNHYIKTKRGFGYYFEENET
CCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCC
>Mature Secondary Structure
MKKILIADDDRAILTLLSYNFRQNDYEVTIVSDGKKAYDKARKNPFDLLLLDLMMPEYSG
CCEEEEECCCHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHCCCCCC
IEVTQKLRKEDNFTPILILTARDDDEMKLTGLSAGSDEYLDKTTPMKEIIVRADALIRRN
HHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHH
QMYNQAPSETVSEALDERPSSLVTDRLVIDFIKKEVTFDEKVLDLTKREFEILELLAKRE
HHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
GKIVSREELLQHFWGISDTAETRTIDVLISKIRKKLNNHYIKTKRGFGYYFEENET
CCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]