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The map label for this gene is potC

Identifier: 15673147

GI number: 15673147

Start: 1177754

End: 1178554

Strand: Direct

Name: potC

Synonym: L177493

Alternate gene names: 15673147

Gene position: 1177754-1178554 (Clockwise)

Preceding gene: 15673146

Following gene: 15673148

Centisome position: 49.79

GC content: 34.46

Gene sequence:

>801_bases
TTGCGAAATAAAAATTCACTTGGTAAAGTTTACCTCACCTTTGTCCTCATCCTTTTATATGCACCTATTTTTTACCTTAT
TTTTTACTCATTCAACTCCGGAAGTGATATGAGCAAATTTACAGGTTTCACATTAGATAATTTCAAAACGTTATTTGCTG
ACAGTCGTCTAATTCTGATTGTTGTTCAAACTTTCTTTCTCGCCTTTTTAAGCTCACTGATTGCTACAGTTATTGGAACA
ATTGGTGCTTTGAACCTTGTTAAATTCAAGAGAAGACGTCGTGAAACTTTACTGGGCTTAAATAATGTCTTAATGGTTTC
CCCAGACGTTGTCATCGGTGCTTCCTTCCTGATTTTATTTACAATTGTTGGAATGAAACTTGGTTTTATGTCTGTTTTAC
TCAGTCATATTGCCTTCTCTATCCCTATTGTTGTTCTGATGGTAATGCCGCTTTATCAAGAAATGGATAGTTCACTCATT
GATGCCGCAAATGATTTAGGGGCAAATTCAAGCCAAATAATGCGTGAAATTACCCTGCCCTATTTAACACCAGGAATTAT
TGCTGGTTTCTTTATGGCATTTACTTATTCTTTAGATGATTTTGCTGTCACTTTCTTTGTCACAGGAAATGATTTCACAA
CTCTATCAGTTGAAATCTATTCCAGAGCTCGCGCCGGAATTTCTTTAGAAATTAATGCCCTTTCTACTCTTGTATTTCTC
TTTTCAATTCTATTAGTTATAGGCTATTATTATATTATGAGAGATTCAGAAACTGTTGGAAAATCTTCAAATCTGACTTA
A

Upstream 100 bases:

>100_bases
CTAACGACACAAAACTGGGGAATGGGTTCAACCATTGCTGTTGTTTTAGTTGTAGCCATGTTGCTTGTCATGAGAATGAC
GAAAGAAAGGAGAGATTGAT

Downstream 100 bases:

>100_bases
AACTATTTTACTGATACTTTGTAGCTCAAAGTATAGAAAGGAGAAACTTGAAAAAATTATCATACTTCTTTGTAGGAATT
TTGATTATTACTGCCTCGTT

Product: spermidine/putrescine ABC transporter permease protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MRNKNSLGKVYLTFVLILLYAPIFYLIFYSFNSGSDMSKFTGFTLDNFKTLFADSRLILIVVQTFFLAFLSSLIATVIGT
IGALNLVKFKRRRRETLLGLNNVLMVSPDVVIGASFLILFTIVGMKLGFMSVLLSHIAFSIPIVVLMVMPLYQEMDSSLI
DAANDLGANSSQIMREITLPYLTPGIIAGFFMAFTYSLDDFAVTFFVTGNDFTTLSVEIYSRARAGISLEINALSTLVFL
FSILLVIGYYYIMRDSETVGKSSNLT

Sequences:

>Translated_266_residues
MRNKNSLGKVYLTFVLILLYAPIFYLIFYSFNSGSDMSKFTGFTLDNFKTLFADSRLILIVVQTFFLAFLSSLIATVIGT
IGALNLVKFKRRRRETLLGLNNVLMVSPDVVIGASFLILFTIVGMKLGFMSVLLSHIAFSIPIVVLMVMPLYQEMDSSLI
DAANDLGANSSQIMREITLPYLTPGIIAGFFMAFTYSLDDFAVTFFVTGNDFTTLSVEIYSRARAGISLEINALSTLVFL
FSILLVIGYYYIMRDSETVGKSSNLT
>Mature_266_residues
MRNKNSLGKVYLTFVLILLYAPIFYLIFYSFNSGSDMSKFTGFTLDNFKTLFADSRLILIVVQTFFLAFLSSLIATVIGT
IGALNLVKFKRRRRETLLGLNNVLMVSPDVVIGASFLILFTIVGMKLGFMSVLLSHIAFSIPIVVLMVMPLYQEMDSSLI
DAANDLGANSSQIMREITLPYLTPGIIAGFFMAFTYSLDDFAVTFFVTGNDFTTLSVEIYSRARAGISLEINALSTLVFL
FSILLVIGYYYIMRDSETVGKSSNLT

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=236, Percent_Identity=36.864406779661, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1787081, Length=248, Percent_Identity=33.4677419354839, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787714, Length=244, Percent_Identity=27.4590163934426, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788764, Length=159, Percent_Identity=28.3018867924528, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29596; Mature: 29596

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNKNSLGKVYLTFVLILLYAPIFYLIFYSFNSGSDMSKFTGFTLDNFKTLFADSRLILI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHCCHHHHH
VVQTFFLAFLSSLIATVIGTIGALNLVKFKRRRRETLLGLNNVLMVSPDVVIGASFLILF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
TIVGMKLGFMSVLLSHIAFSIPIVVLMVMPLYQEMDSSLIDAANDLGANSSQIMREITLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YLTPGIIAGFFMAFTYSLDDFAVTFFVTGNDFTTLSVEIYSRARAGISLEINALSTLVFL
HCCHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEHEEHHHHCCCCEEEHHHHHHHHHH
FSILLVIGYYYIMRDSETVGKSSNLT
HHHHHHHHHHHHHCCCHHCCCCCCCC
>Mature Secondary Structure
MRNKNSLGKVYLTFVLILLYAPIFYLIFYSFNSGSDMSKFTGFTLDNFKTLFADSRLILI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHCCHHHHH
VVQTFFLAFLSSLIATVIGTIGALNLVKFKRRRRETLLGLNNVLMVSPDVVIGASFLILF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
TIVGMKLGFMSVLLSHIAFSIPIVVLMVMPLYQEMDSSLIDAANDLGANSSQIMREITLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YLTPGIIAGFFMAFTYSLDDFAVTFFVTGNDFTTLSVEIYSRARAGISLEINALSTLVFL
HCCHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEHEEHHHHCCCCEEEHHHHHHHHHH
FSILLVIGYYYIMRDSETVGKSSNLT
HHHHHHHHHHHHHCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]