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The map label for this gene is clpX

Identifier: 15673133

GI number: 15673133

Start: 1163884

End: 1165119

Strand: Direct

Name: clpX

Synonym: L163602

Alternate gene names: 15673133

Gene position: 1163884-1165119 (Clockwise)

Preceding gene: 30024025

Following gene: 15673134

Centisome position: 49.2

GC content: 33.5

Gene sequence:

>1236_bases
ATGTCAAATACACAAAATCCAAATATACATTGTTCTTTCTGTGGAAAGAGTCAAGATGATGTAAAAAAATTGATTGCCGG
TTCAGACGTTTATATTTGTAATGAATGTATTGAACTTTCAACTCGAATCTTAGAAGAAGAATTAAGAGAAGAACAAGATT
CAGAAATGCTTGAAGTTAAAACACCTAAAGAAATGTTTGACCATTTAAATGAATATGTGATAGGTCAAGAAAAAGCAAAA
CGTGCACTTGCAGTTGCCGTTTATAATCATTACAAACGAATTAATTTTGCAGCAAGTAAAATTGCTGAAGATATTGAACT
ACAAAAATCAAATATTCTATTAATCGGACCTACCGGTTCTGGTAAGACTTTTCTCGCTCAAACTTTAGCGAAATCACTCA
ACGTTCCATTTGCGATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTTGGAGAAGACGTTGAAAATATTCTCTTA
AAACTTTTACAAGCGAGTGATTTCAATATTGAACGTGCTGAACGTGGAATTATCTATATCGATGAAATTGATAAAATTGC
TAAAAAATCTGAAAATGTATCAATTACTCGTGACGTTTCCGGGGAAGGTGTTCAACAAGCCCTTTTGAAAATTATTGAAG
GAACGGTAGCTAGTGTTCCACCACAAGGTGGACGTAAACATCCTAATCAAGAAATGATTCAAATTGATACCAAAAATATC
TTATTTATTGTTGGTGGAGCTTTTGACGGGATTGAAGAAATTGTCAAACAACGTTTAGGTGAAAAAATTATTGGTTTTGG
TGCCAATAATAAAAAATTAAATGACGATGATTCTTATATGCAAGAAATTATTGCCGAGGACATTCAAAAATTCGGATTAA
TTCCTGAATTTATTGGTCGTCTGCCAATTGTTGCTGCTTTGGAACGTTTGACCGAAGAGGATTTGATTCAAATTTTGACA
GAACCTAAAAATGCTTTGATTAAACAATATAAACAACTCCTTTTATTTGATAATGTTGAACTTGAATTTGAAGATGAAGC
CCTCATGGCAATTGCTAGAAAAGCAATTGAGCGCAAAACAGGAGCGCGTGGACTTCGTTCAATTATTGAAGAAGTAATGA
TGGATATCATGTTTGAAGTTCCAAGTCATGAAGAAATTACAAAAGTTATTATTAATGAAGCAGTTGTTGACGGAAAAGCT
GAGCCACAAATGATTCGAGAGGCCAAGAAAAAATGA

Upstream 100 bases:

>100_bases
GCTTTTTCTGGAACTTTATTTTAAAAAATAAAAAAAGTGCCTTTTAAGTAAGCCAATAACACTTACTTTTTATGTTAGTG
AAATCAGGAATAAAATAACT

Downstream 100 bases:

>100_bases
CCATAAATACAAATAATCTGACAATAACAATTTCAGCAGCATCAAAAAAACAATATCCAGAAAATGATTGGCCAGAAATT
GCCTTAGCTGGGCGTTCAAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSNTQNPNIHCSFCGKSQDDVKKLIAGSDVYICNECIELSTRILEEELREEQDSEMLEVKTPKEMFDHLNEYVIGQEKAK
RALAVAVYNHYKRINFAASKIAEDIELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILL
KLLQASDFNIERAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLNDDDSYMQEIIAEDIQKFGLIPEFIGRLPIVAALERLTEEDLIQILT
EPKNALIKQYKQLLLFDNVELEFEDEALMAIARKAIERKTGARGLRSIIEEVMMDIMFEVPSHEEITKVIINEAVVDGKA
EPQMIREAKKK

Sequences:

>Translated_411_residues
MSNTQNPNIHCSFCGKSQDDVKKLIAGSDVYICNECIELSTRILEEELREEQDSEMLEVKTPKEMFDHLNEYVIGQEKAK
RALAVAVYNHYKRINFAASKIAEDIELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILL
KLLQASDFNIERAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLNDDDSYMQEIIAEDIQKFGLIPEFIGRLPIVAALERLTEEDLIQILT
EPKNALIKQYKQLLLFDNVELEFEDEALMAIARKAIERKTGARGLRSIIEEVMMDIMFEVPSHEEITKVIINEAVVDGKA
EPQMIREAKKK
>Mature_410_residues
SNTQNPNIHCSFCGKSQDDVKKLIAGSDVYICNECIELSTRILEEELREEQDSEMLEVKTPKEMFDHLNEYVIGQEKAKR
ALAVAVYNHYKRINFAASKIAEDIELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
LLQASDFNIERAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNIL
FIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLNDDDSYMQEIIAEDIQKFGLIPEFIGRLPIVAALERLTEEDLIQILTE
PKNALIKQYKQLLLFDNVELEFEDEALMAIARKAIERKTGARGLRSIIEEVMMDIMFEVPSHEEITKVIINEAVVDGKAE
PQMIREAKKK

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=332, Percent_Identity=49.0963855421687, Blast_Score=324, Evalue=7e-89,
Organism=Escherichia coli, GI1786642, Length=402, Percent_Identity=60.9452736318408, Blast_Score=503, Evalue=1e-143,
Organism=Escherichia coli, GI1790366, Length=211, Percent_Identity=34.1232227488152, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982905, Length=319, Percent_Identity=44.5141065830721, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71982908, Length=319, Percent_Identity=44.5141065830721, Blast_Score=274, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=392, Percent_Identity=40.3061224489796, Blast_Score=263, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI71988660, Length=252, Percent_Identity=42.4603174603175, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6319704, Length=436, Percent_Identity=39.2201834862385, Blast_Score=268, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24648291, Length=324, Percent_Identity=46.6049382716049, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24648289, Length=324, Percent_Identity=46.6049382716049, Blast_Score=306, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_LACLA (Q9CGE6)

Other databases:

- EMBL:   AE005176
- PIR:   G86768
- RefSeq:   NP_267307.1
- ProteinModelPortal:   Q9CGE6
- GeneID:   1114793
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L163602
- NMPDR:   fig|272623.1.peg.1185
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   LLAC272623:L163602-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 45977; Mature: 45846

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTQNPNIHCSFCGKSQDDVKKLIAGSDVYICNECIELSTRILEEELREEQDSEMLEVK
CCCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
TPKEMFDHLNEYVIGQEKAKRALAVAVYNHYKRINFAASKIAEDIELQKSNILLIGPTGS
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
GKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLLQASDFNIERAERGIIYI
CHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCEEEE
DEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCE
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLNDDDSYMQEIIAEDIQKFGLIPEFIGR
EEEECCCHHHHHHHHHHHHCCHHEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCC
LPIVAALERLTEEDLIQILTEPKNALIKQYKQLLLFDNVELEFEDEALMAIARKAIERKT
CHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHH
GARGLRSIIEEVMMDIMFEVPSHEEITKVIINEAVVDGKAEPQMIREAKKK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SNTQNPNIHCSFCGKSQDDVKKLIAGSDVYICNECIELSTRILEEELREEQDSEMLEVK
CCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
TPKEMFDHLNEYVIGQEKAKRALAVAVYNHYKRINFAASKIAEDIELQKSNILLIGPTGS
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
GKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLLQASDFNIERAERGIIYI
CHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCCEEEE
DEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCE
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLNDDDSYMQEIIAEDIQKFGLIPEFIGR
EEEECCCHHHHHHHHHHHHCCHHEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCC
LPIVAALERLTEEDLIQILTEPKNALIKQYKQLLLFDNVELEFEDEALMAIARKAIERKT
CHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHH
GARGLRSIIEEVMMDIMFEVPSHEEITKVIINEAVVDGKAEPQMIREAKKK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471