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The map label for this gene is dcdA

Identifier: 15673123

GI number: 15673123

Start: 1155388

End: 1155831

Strand: Direct

Name: dcdA

Synonym: L155044

Alternate gene names: 15673123

Gene position: 1155388-1155831 (Clockwise)

Preceding gene: 15673122

Following gene: 15673124

Centisome position: 48.84

GC content: 37.16

Gene sequence:

>444_bases
ATGATGTCAGAGAAATTTACAAGACCAAGTAAAGATGAATATTTTAAAGAAATTGTCCAAGTGGTTGCAAAACGATCAAC
TTGTAACCATGCTCAAGTAGGAGCTTTATTGGTCAGTCCTAATGGTCAACTTCTCTCTACGGGATATAATGGTGCGGTTT
CGGGGATGCCACATTGTACAGATATTGGTTGTACTGAAGATAAATATGGACACTGTGTAGCAACGGTTCATGCAGAACAA
AATGCGATTGCTCAAGCTGCTAAACATGGCGTTTCACCTGAAGGTGCGATTTTATATACAACGTTATTTCCTTGCCTTGC
CTGCCTGAAATTAGTTGTTGCTGCTGGTGTGAAAGAAATTAAATACATTGATGAGTATCATGCTAAAGATCCTTATGAAG
AATTATTGATTGATACTTTAGAAATCGCCTGTGAAAAAATTTAA

Upstream 100 bases:

>100_bases
TTTTTCTTCCAAGTTAATTTATGATTCTCTTGGAAGTTTTTTTATTAAGCCTGAAATAAATAAATTTGCTATAATAAATC
AAAAAGCAATTAAGGAGTTC

Downstream 100 bases:

>100_bases
TTAGCTCTGAGAACTTTAAAAACTCTGGCTAATAGATGAGCAATTTATGAAAATTGCTCTTTTTTTTGCTAAAATAGAAG
GCGAGGTTATCATAAAATGG

Product: dCMP deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MMSEKFTRPSKDEYFKEIVQVVAKRSTCNHAQVGALLVSPNGQLLSTGYNGAVSGMPHCTDIGCTEDKYGHCVATVHAEQ
NAIAQAAKHGVSPEGAILYTTLFPCLACLKLVVAAGVKEIKYIDEYHAKDPYEELLIDTLEIACEKI

Sequences:

>Translated_147_residues
MMSEKFTRPSKDEYFKEIVQVVAKRSTCNHAQVGALLVSPNGQLLSTGYNGAVSGMPHCTDIGCTEDKYGHCVATVHAEQ
NAIAQAAKHGVSPEGAILYTTLFPCLACLKLVVAAGVKEIKYIDEYHAKDPYEELLIDTLEIACEKI
>Mature_147_residues
MMSEKFTRPSKDEYFKEIVQVVAKRSTCNHAQVGALLVSPNGQLLSTGYNGAVSGMPHCTDIGCTEDKYGHCVATVHAEQ
NAIAQAAKHGVSPEGAILYTTLFPCLACLKLVVAAGVKEIKYIDEYHAKDPYEELLIDTLEIACEKI

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=133, Percent_Identity=34.5864661654135, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI61742821, Length=133, Percent_Identity=34.5864661654135, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321938, Length=134, Percent_Identity=32.089552238806, Blast_Score=74, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24667298, Length=136, Percent_Identity=33.0882352941176, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667302, Length=136, Percent_Identity=33.0882352941176, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 15975; Mature: 15975

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSEKFTRPSKDEYFKEIVQVVAKRSTCNHAQVGALLVSPNGQLLSTGYNGAVSGMPHCT
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHCEEEECCCCCEEECCCCCCCCCCCCCC
DIGCTEDKYGHCVATVHAEQNAIAQAAKHGVSPEGAILYTTLFPCLACLKLVVAAGVKEI
CCCCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KYIDEYHAKDPYEELLIDTLEIACEKI
HHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMSEKFTRPSKDEYFKEIVQVVAKRSTCNHAQVGALLVSPNGQLLSTGYNGAVSGMPHCT
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHCEEEECCCCCEEECCCCCCCCCCCCCC
DIGCTEDKYGHCVATVHAEQNAIAQAAKHGVSPEGAILYTTLFPCLACLKLVVAAGVKEI
CCCCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KYIDEYHAKDPYEELLIDTLEIACEKI
HHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]