Click here to switch to the map view.

The map label for this gene is frdC

Identifier: 15673106

GI number: 15673106

Start: 1137875

End: 1139383

Strand: Direct

Name: frdC

Synonym: L137630

Alternate gene names: 15673106

Gene position: 1137875-1139383 (Clockwise)

Preceding gene: 15673105

Following gene: 15673107

Centisome position: 48.1

GC content: 37.64

Gene sequence:

>1509_bases
ATGAAAATTTGGACTAAACTAGGCTTGCTAACGCTTGTGGGCCTCTCTTTGACTTCTTGTGGGAGTAATACAAAGAATAC
AAAAGGACAATCAAGTTCGTCTCAGAAAGTTGAAACCTCGGCTGGTGCAAGTAAATCAAACATCTATGCTGATCCTTCTA
CTTTAAGTGATAAATACGATGTGATTATTGTTGGTTCTGGTGGGGCTGGAATGACTGCAGCAATTGAAGCAAAAGATGCT
GGAATGAATCCAGTCATTTTAGAAAAAATGCCAATTGCTGGTGGAAATACTTCAAAAGCCTCAGCTGGTTTGAACGCATC
AGAAACATCAGTCGAAAAAGCACAAGGTGTCGCTGATTCAAATGATAAATTTTATGAAGAAACGCTCAAAGGTGGTGGTG
GTACGAATGACAAGGCACTCCTTCGTTATTTTGTTGACCACTCGGCTGGTGCTGTTGATTGGTTAAATACAAATGGAATT
GTTTTAGATAATTTAACTACGACAGGGGGAATGTCAGTTTCAAGAACTCACCGACCACATGATGGTTCAGCAGTTGGTGG
TTATTTGGTAAAAGGTCTTGAAGAAAATATTACCAAACGAAATATTCCCTTATTTGTAAATAGTGATGTTACCAAAATTA
CTGAAAAAGATGGTAAAGTATCTGGAGTTAAAGTTAAGATTGAGGGTGAAACTAAAGATATTTCTTCTAAAGCAGTCGTT
GTTACAACAGGTGGATTCGGTGCAAATAAGAAAATGATTGCAAAATATCGTCCTGACCTTAAAGATTATGTGACAACAAA
TGCGGCTGGTTCAACTGGTGACGGAATTACTATGATTTCAGAACTTGGTGGGGAATTAGTTGACATGGATAAAATTCAAA
TTCATCCAACTGTATTCCAAAAAACAGGTTATCTTGTTTCAGAATCAATTCGTGGTGAAGGGGCGATTCTTGTAAATCAA
AAAGGGAAACGTTTCTTTAATGAAATGGATACTCGTGATAAAGTTTCTGCTGCTGAACTTAAACAACCAGGAAAATATTC
TTATGTTATTTTTGGAGAAGGAACTAAAGATAAAGTAAAAGCAGTTGAACAGTATATATCTAAAGATATGGTCGTTGAAG
CTGACAGTATCAAGGGACTTGCTGACAAGCTCGACATTAATGAAAAAGCACTGACTTCAACAATTGATGGTTGGAACAAA
GCTGTATCAACTAAAAAAGATGAAGACTTTGGTCGTACAACAGGAATGACTACTGAAGTATCAGGTAAGTATTATGCCAT
TAAAGTGGCTCCAGGAATTCACCATACAATGGCTGGGGTAAAAATTAATACAAATACTCAAGTCTTGAAAAAAGATGGTA
GTCCAATTCAAGGATTATATGCTGCCGGAGAAGTTACAGGTGGTCTCCATGGTGGTAACCGCATTGGTGGTAACGCTGTT
GCTGATATTGTTATCTTTGGACGACAAGCTGGAACTCAATCTGCGGCCTATGCTAAAACAAGCAATTAA

Upstream 100 bases:

>100_bases
AAATATTTTTAATGACAGCTAAAAATTTTATAGATATTTGGAAAGTTGCTAAAAATTTGTTATAATAACTATGTGAATTT
TAACACAAAAGGAGTAATTT

Downstream 100 bases:

>100_bases
TATTTACTTATAAGTAGTTATTAAGAATAAAAGTTACTGACGGAGTATTTGTCAGTAACTTTTTGTATTATTAAGATTGA
TTAAAGGTAAATTCTTTGAA

Product: fumarate reductase flavoprotein subunit

Products: NA

Alternate protein names: Flavocytochrome c; Flavocytochrome c3; Fcc3 [H]

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MKIWTKLGLLTLVGLSLTSCGSNTKNTKGQSSSSQKVETSAGASKSNIYADPSTLSDKYDVIIVGSGGAGMTAAIEAKDA
GMNPVILEKMPIAGGNTSKASAGLNASETSVEKAQGVADSNDKFYEETLKGGGGTNDKALLRYFVDHSAGAVDWLNTNGI
VLDNLTTTGGMSVSRTHRPHDGSAVGGYLVKGLEENITKRNIPLFVNSDVTKITEKDGKVSGVKVKIEGETKDISSKAVV
VTTGGFGANKKMIAKYRPDLKDYVTTNAAGSTGDGITMISELGGELVDMDKIQIHPTVFQKTGYLVSESIRGEGAILVNQ
KGKRFFNEMDTRDKVSAAELKQPGKYSYVIFGEGTKDKVKAVEQYISKDMVVEADSIKGLADKLDINEKALTSTIDGWNK
AVSTKKDEDFGRTTGMTTEVSGKYYAIKVAPGIHHTMAGVKINTNTQVLKKDGSPIQGLYAAGEVTGGLHGGNRIGGNAV
ADIVIFGRQAGTQSAAYAKTSN

Sequences:

>Translated_502_residues
MKIWTKLGLLTLVGLSLTSCGSNTKNTKGQSSSSQKVETSAGASKSNIYADPSTLSDKYDVIIVGSGGAGMTAAIEAKDA
GMNPVILEKMPIAGGNTSKASAGLNASETSVEKAQGVADSNDKFYEETLKGGGGTNDKALLRYFVDHSAGAVDWLNTNGI
VLDNLTTTGGMSVSRTHRPHDGSAVGGYLVKGLEENITKRNIPLFVNSDVTKITEKDGKVSGVKVKIEGETKDISSKAVV
VTTGGFGANKKMIAKYRPDLKDYVTTNAAGSTGDGITMISELGGELVDMDKIQIHPTVFQKTGYLVSESIRGEGAILVNQ
KGKRFFNEMDTRDKVSAAELKQPGKYSYVIFGEGTKDKVKAVEQYISKDMVVEADSIKGLADKLDINEKALTSTIDGWNK
AVSTKKDEDFGRTTGMTTEVSGKYYAIKVAPGIHHTMAGVKINTNTQVLKKDGSPIQGLYAAGEVTGGLHGGNRIGGNAV
ADIVIFGRQAGTQSAAYAKTSN
>Mature_502_residues
MKIWTKLGLLTLVGLSLTSCGSNTKNTKGQSSSSQKVETSAGASKSNIYADPSTLSDKYDVIIVGSGGAGMTAAIEAKDA
GMNPVILEKMPIAGGNTSKASAGLNASETSVEKAQGVADSNDKFYEETLKGGGGTNDKALLRYFVDHSAGAVDWLNTNGI
VLDNLTTTGGMSVSRTHRPHDGSAVGGYLVKGLEENITKRNIPLFVNSDVTKITEKDGKVSGVKVKIEGETKDISSKAVV
VTTGGFGANKKMIAKYRPDLKDYVTTNAAGSTGDGITMISELGGELVDMDKIQIHPTVFQKTGYLVSESIRGEGAILVNQ
KGKRFFNEMDTRDKVSAAELKQPGKYSYVIFGEGTKDKVKAVEQYISKDMVVEADSIKGLADKLDINEKALTSTIDGWNK
AVSTKKDEDFGRTTGMTTEVSGKYYAIKVAPGIHHTMAGVKINTNTQVLKKDGSPIQGLYAAGEVTGGLHGGNRIGGNAV
ADIVIFGRQAGTQSAAYAKTSN

Specific function: Catalyzes fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown, but evidence indicates that flavocytochrome c participates in electron transfer from formate to fumarate and possibly also to tr

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=437, Percent_Identity=25.858123569794, Blast_Score=116, Evalue=5e-26,
Organism=Escherichia coli, GI1790597, Length=410, Percent_Identity=29.0243902439024, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788928, Length=470, Percent_Identity=26.3829787234043, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1786942, Length=288, Percent_Identity=28.125, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71986328, Length=470, Percent_Identity=33.4042553191489, Blast_Score=244, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17505833, Length=434, Percent_Identity=25.5760368663594, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17550100, Length=492, Percent_Identity=26.4227642276423, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320788, Length=463, Percent_Identity=35.6371490280778, Blast_Score=239, Evalue=9e-64,
Organism=Saccharomyces cerevisiae, GI6322511, Length=467, Percent_Identity=34.0471092077088, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6322701, Length=457, Percent_Identity=23.6323851203501, Blast_Score=97, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6322416, Length=468, Percent_Identity=24.3589743589744, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17137288, Length=479, Percent_Identity=25.8872651356994, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655642, Length=479, Percent_Identity=25.8872651356994, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655647, Length=479, Percent_Identity=25.8872651356994, Blast_Score=104, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031
- InterPro:   IPR012286
- InterPro:   IPR007087 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 52853; Mature: 52853

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIWTKLGLLTLVGLSLTSCGSNTKNTKGQSSSSQKVETSAGASKSNIYADPSTLSDKYD
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHCCCCCCCEEECCCCCCCCCC
VIIVGSGGAGMTAAIEAKDAGMNPVILEKMPIAGGNTSKASAGLNASETSVEKAQGVADS
EEEEECCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
NDKFYEETLKGGGGTNDKALLRYFVDHSAGAVDWLNTNGIVLDNLTTTGGMSVSRTHRPH
CHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCEECCCCCCC
DGSAVGGYLVKGLEENITKRNIPLFVNSDVTKITEKDGKVSGVKVKIEGETKDISSKAVV
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHCCCCCEEEEEEEECCCCCCCCCCEEE
VTTGGFGANKKMIAKYRPDLKDYVTTNAAGSTGDGITMISELGGELVDMDKIQIHPTVFQ
EEECCCCCCCCCHHHCCCCHHHHHCCCCCCCCCCCCHHHHHCCCCEEECCEEEECCCHHH
KTGYLVSESIRGEGAILVNQKGKRFFNEMDTRDKVSAAELKQPGKYSYVIFGEGTKDKVK
HCCCEEECCCCCCCEEEECCCCHHHHHHCCCCCCCCHHHHCCCCCEEEEEEECCCHHHHH
AVEQYISKDMVVEADSIKGLADKLDINEKALTSTIDGWNKAVSTKKDEDFGRTTGMTTEV
HHHHHHCCCEEEEHHHCCCHHHHCCCCHHHHHHHHCCHHHHHCCCCCCCCCCCCCCEEEE
SGKYYAIKVAPGIHHTMAGVKINTNTQVLKKDGSPIQGLYAAGEVTGGLHGGNRIGGNAV
CCCEEEEEECCCCCHHHCCCEECCCCEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCE
ADIVIFGRQAGTQSAAYAKTSN
EEEEEEECCCCCCCCCEEECCC
>Mature Secondary Structure
MKIWTKLGLLTLVGLSLTSCGSNTKNTKGQSSSSQKVETSAGASKSNIYADPSTLSDKYD
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHCCCCCCCEEECCCCCCCCCC
VIIVGSGGAGMTAAIEAKDAGMNPVILEKMPIAGGNTSKASAGLNASETSVEKAQGVADS
EEEEECCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
NDKFYEETLKGGGGTNDKALLRYFVDHSAGAVDWLNTNGIVLDNLTTTGGMSVSRTHRPH
CHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCEECCCCCCC
DGSAVGGYLVKGLEENITKRNIPLFVNSDVTKITEKDGKVSGVKVKIEGETKDISSKAVV
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHCCCCCEEEEEEEECCCCCCCCCCEEE
VTTGGFGANKKMIAKYRPDLKDYVTTNAAGSTGDGITMISELGGELVDMDKIQIHPTVFQ
EEECCCCCCCCCHHHCCCCHHHHHCCCCCCCCCCCCHHHHHCCCCEEECCEEEECCCHHH
KTGYLVSESIRGEGAILVNQKGKRFFNEMDTRDKVSAAELKQPGKYSYVIFGEGTKDKVK
HCCCEEECCCCCCCEEEECCCCHHHHHHCCCCCCCCHHHHCCCCCEEEEEEECCCHHHHH
AVEQYISKDMVVEADSIKGLADKLDINEKALTSTIDGWNKAVSTKKDEDFGRTTGMTTEV
HHHHHHCCCEEEEHHHCCCHHHHCCCCHHHHHHHHCCHHHHHCCCCCCCCCCCCCCEEEE
SGKYYAIKVAPGIHHTMAGVKINTNTQVLKKDGSPIQGLYAAGEVTGGLHGGNRIGGNAV
CCCEEEEEECCCCCHHHCCCEECCCCEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCE
ADIVIFGRQAGTQSAAYAKTSN
EEEEEEECCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1333793 [H]