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The map label for this gene is ribG

Identifier: 15672975

GI number: 15672975

Start: 1022028

End: 1023116

Strand: Direct

Name: ribG

Synonym: L0163

Alternate gene names: 15672975

Gene position: 1022028-1023116 (Clockwise)

Preceding gene: 15672974

Following gene: 15672976

Centisome position: 43.2

GC content: 37.74

Gene sequence:

>1089_bases
ATGAAAAAAGACGAATACTACATGGATTTAGCAATTGTACTTGCAAACAAAGGAGGTGGTAATGTCAACCCTAACCCTCA
AGTAGGAGCCCTTATTGTCAAAGAAGGGAGAATTATTGGTCAAGGTTATCATGAAAAATATGGGAAAGCTCACGCGGAAA
TCAATGCTTTTAAGGATTGTAACGAATCTCCCGAAGGAGCCACGCTTTATGTGACCTTAGAGCCTTGTGCGCATCAGGGA
AAACAACCCCCTTGTTTTGAAGCGATTATAAAAAATGGAATTAAGCGTGTTGTTATCGGGCATTTAGACCCCAATCCCTT
GGTTTCAGGAAAAGGAATTAAAGCAATGAGAGAAGCTGGAATTGAAGTTTCTCTCAATGTTTTAGAAAAAGAATGTGAAG
AATTAAATAAAATTTTCTTTTATTATGTTAGTCAAGGGCTTCCCTATGTCATGATGAAGTATGTAATGACTTTAGACGGA
AAAATTGCGACATCAGCAGGTCAATCAAAATGGATTACAGGTGAAATTGCAAGACAGAAAGTACATCAAGACCGTTCACG
TTTTATGGCAATTATGATTGGTGTTGAAACGCTTATTTTAGATGATCCACAACTCTCTGTCAGGTTGGAAAATGGAAAAA
ATCCGATAAGAATCATTTGTGATACTCATTTAAGAAGTCCTTTGGCTTCCAAGATTGTTTCCACAGCTACTGAAATTCCA
ACGATTATTGCTACAGCTGAGTCTGACCCCGAAAAACAAGCTCCCTTTCTTAAAGCGGGTTGTGAAATTATCTTAGTTTC
TTGCCTAGAAGGAAGATTGAATTTGAAAGAATTGACCAAAAAGTTAGGAGAAAAGGGGATTGACAGTATCATCTTGGAAG
GTGGAGGAACATTAAATGCTTCGGCATTAAAAGCAGGGATAGTCCAAAAAGTTCAAACTTATATTGCCCTTAAAATATTT
GGTGGAAAAGAAGCACCAAGTCCAGTTGAAGGACATGGAATCGAGCAACCCAATCAAGCCTATCTCCTAGAAGGGGCTCA
AATAACCTATCTAGGAGAAGATATTTTATTAGAAAGTGAGCTTCTTTAA

Upstream 100 bases:

>100_bases
TTTTTGAGCTGCTTTTTTGCTCAAAAAAAAATAGAAAATTTATCAAAAGACCCTGAAATTTTATTTTAGGGTCTTATTTT
TTATTAGAAAGGATGAATAG

Downstream 100 bases:

>100_bases
TGTTTACAGGAATAATTGAAGAATTAGGGGAAGTGAGTCGCCTGCAAAAAAGAGAAAAATCCTTCAAAATTAGTATCCGT
GCTTCCTTGATTTTAGAGGA

Product: riboflavin-specific deaminase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKKDEYYMDLAIVLANKGGGNVNPNPQVGALIVKEGRIIGQGYHEKYGKAHAEINAFKDCNESPEGATLYVTLEPCAHQG
KQPPCFEAIIKNGIKRVVIGHLDPNPLVSGKGIKAMREAGIEVSLNVLEKECEELNKIFFYYVSQGLPYVMMKYVMTLDG
KIATSAGQSKWITGEIARQKVHQDRSRFMAIMIGVETLILDDPQLSVRLENGKNPIRIICDTHLRSPLASKIVSTATEIP
TIIATAESDPEKQAPFLKAGCEIILVSCLEGRLNLKELTKKLGEKGIDSIILEGGGTLNASALKAGIVQKVQTYIALKIF
GGKEAPSPVEGHGIEQPNQAYLLEGAQITYLGEDILLESELL

Sequences:

>Translated_362_residues
MKKDEYYMDLAIVLANKGGGNVNPNPQVGALIVKEGRIIGQGYHEKYGKAHAEINAFKDCNESPEGATLYVTLEPCAHQG
KQPPCFEAIIKNGIKRVVIGHLDPNPLVSGKGIKAMREAGIEVSLNVLEKECEELNKIFFYYVSQGLPYVMMKYVMTLDG
KIATSAGQSKWITGEIARQKVHQDRSRFMAIMIGVETLILDDPQLSVRLENGKNPIRIICDTHLRSPLASKIVSTATEIP
TIIATAESDPEKQAPFLKAGCEIILVSCLEGRLNLKELTKKLGEKGIDSIILEGGGTLNASALKAGIVQKVQTYIALKIF
GGKEAPSPVEGHGIEQPNQAYLLEGAQITYLGEDILLESELL
>Mature_362_residues
MKKDEYYMDLAIVLANKGGGNVNPNPQVGALIVKEGRIIGQGYHEKYGKAHAEINAFKDCNESPEGATLYVTLEPCAHQG
KQPPCFEAIIKNGIKRVVIGHLDPNPLVSGKGIKAMREAGIEVSLNVLEKECEELNKIFFYYVSQGLPYVMMKYVMTLDG
KIATSAGQSKWITGEIARQKVHQDRSRFMAIMIGVETLILDDPQLSVRLENGKNPIRIICDTHLRSPLASKIVSTATEIP
TIIATAESDPEKQAPFLKAGCEIILVSCLEGRLNLKELTKKLGEKGIDSIILEGGGTLNASALKAGIVQKVQTYIALKIF
GGKEAPSPVEGHGIEQPNQAYLLEGAQITYLGEDILLESELL

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=369, Percent_Identity=37.3983739837398, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI145693172, Length=154, Percent_Identity=33.1168831168831, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39439; Mature: 39439

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKDEYYMDLAIVLANKGGGNVNPNPQVGALIVKEGRIIGQGYHEKYGKAHAEINAFKDC
CCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEECCEEECCCHHHHHCHHHHHHHHHHCC
NESPEGATLYVTLEPCAHQGKQPPCFEAIIKNGIKRVVIGHLDPNPLVSGKGIKAMREAG
CCCCCCCEEEEEECHHHCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHCC
IEVSLNVLEKECEELNKIFFYYVSQGLPYVMMKYVMTLDGKIATSAGQSKWITGEIARQK
CEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCEEHHHHHHHH
VHQDRSRFMAIMIGVETLILDDPQLSVRLENGKNPIRIICDTHLRSPLASKIVSTATEIP
HHHHHHHHHHHEEEHEEEEECCCCEEEEECCCCCCEEEEECCHHCCHHHHHHHHHHHHCC
TIIATAESDPEKQAPFLKAGCEIILVSCLEGRLNLKELTKKLGEKGIDSIILEGGGTLNA
EEEEECCCCCHHCCCHHHHCHHHEEEEHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCH
SALKAGIVQKVQTYIALKIFGGKEAPSPVEGHGIEQPNQAYLLEGAQITYLGEDILLESE
HHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCEEEEECCHHEECCC
LL
CC
>Mature Secondary Structure
MKKDEYYMDLAIVLANKGGGNVNPNPQVGALIVKEGRIIGQGYHEKYGKAHAEINAFKDC
CCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEECCEEECCCHHHHHCHHHHHHHHHHCC
NESPEGATLYVTLEPCAHQGKQPPCFEAIIKNGIKRVVIGHLDPNPLVSGKGIKAMREAG
CCCCCCCEEEEEECHHHCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHCC
IEVSLNVLEKECEELNKIFFYYVSQGLPYVMMKYVMTLDGKIATSAGQSKWITGEIARQK
CEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCEEHHHHHHHH
VHQDRSRFMAIMIGVETLILDDPQLSVRLENGKNPIRIICDTHLRSPLASKIVSTATEIP
HHHHHHHHHHHEEEHEEEEECCCCEEEEECCCCCCEEEEECCHHCCHHHHHHHHHHHHCC
TIIATAESDPEKQAPFLKAGCEIILVSCLEGRLNLKELTKKLGEKGIDSIILEGGGTLNA
EEEEECCCCCHHCCCHHHHCHHHEEEEHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCH
SALKAGIVQKVQTYIALKIFGGKEAPSPVEGHGIEQPNQAYLLEGAQITYLGEDILLESE
HHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCEEEEECCHHEECCC
LL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]