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The map label for this gene is dnaQ

Identifier: 15672964

GI number: 15672964

Start: 1009341

End: 1010174

Strand: Direct

Name: dnaQ

Synonym: L9094

Alternate gene names: 15672964

Gene position: 1009341-1010174 (Clockwise)

Preceding gene: 15672963

Following gene: 15672965

Centisome position: 42.67

GC content: 33.09

Gene sequence:

>834_bases
ATGTCTGAGAAATATGTCGTATTTGACTTTGAAACTACAGGATTTTCTGCACAAAAAAATGAAATTATTCAAATTGGAGC
GGTAAAATATGATGAGAATAATCAAGAGCAAGCTAGATTTAATCAGTTAGTAAAAAATCAACGCTCTTATGTCTCAACTG
AAATCACTCAATTGACTGGCATAAAACCAGCTGATTTGTTAAATCAACCAACGATTGAAGAAATTTTACCTGAATTTTTA
GACTTCATCAAAGGTCATTTATTAGTGGCTCATAATGCTCCTTTTGATATTTCTTTTCTTTATCAGGCCATTATTGATTG
TGCAATTACTGATGTTGAGGCTTTTCGTGTCTATGATACTTTGGCAGAAAGTAAAAAGTTATTAACTATGTCTTCTTATG
CTCTAGAAAATTTTAAAGACCTACTAGAAATGAATGATTTACGTTCGCATGATGCGCTCAACGACTGCTTAATCACGGCA
AAACTTTATCAATATTTACAGAAAATTGAAGAAGTTGAGCTGTCAGTAGAATCAGAAGTTACTGACGAACTCGGTCAGTT
AGATTTATTTGGTGACAGCTCTGATGAAATTACTGACAGCCTTCGCAGAAAGTTAAATTTACCAATCACCAAAGCTTTAG
TCTATTATCAGCAAAATCTTGAGCGAAAATGGGAACGATTTGAAGTTCTTGGAATTTCGATTGAACGAGAGTACTCCGTA
GGTTCGAGTTTAAATATTCGTTTACATAATTCAGAGAAAGTGAAAATTCATTCTGATTTTCTAAAAGAAATGCAAAAAGC
CAATTTCGTGACGATTATGGAGGAAGAAAAATGA

Upstream 100 bases:

>100_bases
GACAGAAAGTTAAAAAACTTCCAGAAAACAAAAACTGACGAAATACCAAAATTTGGGAAATTAATTAAAACAAAAGAAAT
TATCGAGGAACTGAATAAAA

Downstream 100 bases:

>100_bases
CAGCAATTTGGAAAGAAAAAAGTTTTAATCAACTTACATTAGATGAAATGTATCAACTTTTAAGCCTGCGTACTGCTGTC
TTTGTTGTGGAGCAAAACTG

Product: DNA polymerase III, epsilon chain

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSEKYVVFDFETTGFSAQKNEIIQIGAVKYDENNQEQARFNQLVKNQRSYVSTEITQLTGIKPADLLNQPTIEEILPEFL
DFIKGHLLVAHNAPFDISFLYQAIIDCAITDVEAFRVYDTLAESKKLLTMSSYALENFKDLLEMNDLRSHDALNDCLITA
KLYQYLQKIEEVELSVESEVTDELGQLDLFGDSSDEITDSLRRKLNLPITKALVYYQQNLERKWERFEVLGISIEREYSV
GSSLNIRLHNSEKVKIHSDFLKEMQKANFVTIMEEEK

Sequences:

>Translated_277_residues
MSEKYVVFDFETTGFSAQKNEIIQIGAVKYDENNQEQARFNQLVKNQRSYVSTEITQLTGIKPADLLNQPTIEEILPEFL
DFIKGHLLVAHNAPFDISFLYQAIIDCAITDVEAFRVYDTLAESKKLLTMSSYALENFKDLLEMNDLRSHDALNDCLITA
KLYQYLQKIEEVELSVESEVTDELGQLDLFGDSSDEITDSLRRKLNLPITKALVYYQQNLERKWERFEVLGISIEREYSV
GSSLNIRLHNSEKVKIHSDFLKEMQKANFVTIMEEEK
>Mature_276_residues
SEKYVVFDFETTGFSAQKNEIIQIGAVKYDENNQEQARFNQLVKNQRSYVSTEITQLTGIKPADLLNQPTIEEILPEFLD
FIKGHLLVAHNAPFDISFLYQAIIDCAITDVEAFRVYDTLAESKKLLTMSSYALENFKDLLEMNDLRSHDALNDCLITAK
LYQYLQKIEEVELSVESEVTDELGQLDLFGDSSDEITDSLRRKLNLPITKALVYYQQNLERKWERFEVLGISIEREYSVG
SSLNIRLHNSEKVKIHSDFLKEMQKANFVTIMEEEK

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI1786409, Length=194, Percent_Identity=29.8969072164948, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR023223
- InterPro:   IPR016027
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 32046; Mature: 31914

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKYVVFDFETTGFSAQKNEIIQIGAVKYDENNQEQARFNQLVKNQRSYVSTEITQLTG
CCCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
IKPADLLNQPTIEEILPEFLDFIKGHLLVAHNAPFDISFLYQAIIDCAITDVEAFRVYDT
CCCHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAESKKLLTMSSYALENFKDLLEMNDLRSHDALNDCLITAKLYQYLQKIEEVELSVESEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDELGQLDLFGDSSDEITDSLRRKLNLPITKALVYYQQNLERKWERFEVLGISIEREYSV
HHHHCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCC
GSSLNIRLHNSEKVKIHSDFLKEMQKANFVTIMEEEK
CCEEEEEEECCCEEEEHHHHHHHHHHCCEEEEEECCC
>Mature Secondary Structure 
SEKYVVFDFETTGFSAQKNEIIQIGAVKYDENNQEQARFNQLVKNQRSYVSTEITQLTG
CCCEEEEEEECCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
IKPADLLNQPTIEEILPEFLDFIKGHLLVAHNAPFDISFLYQAIIDCAITDVEAFRVYDT
CCCHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAESKKLLTMSSYALENFKDLLEMNDLRSHDALNDCLITAKLYQYLQKIEEVELSVESEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDELGQLDLFGDSSDEITDSLRRKLNLPITKALVYYQQNLERKWERFEVLGISIEREYSV
HHHHCCEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCC
GSSLNIRLHNSEKVKIHSDFLKEMQKANFVTIMEEEK
CCEEEEEEECCCEEEEHHHHHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]