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The map label for this gene is ftsX

Identifier: 15672955

GI number: 15672955

Start: 1000271

End: 1001206

Strand: Direct

Name: ftsX

Synonym: L2.1N

Alternate gene names: 15672955

Gene position: 1000271-1001206 (Clockwise)

Preceding gene: 15672954

Following gene: 15672961

Centisome position: 42.28

GC content: 35.58

Gene sequence:

>936_bases
ATGATTAGAAATTTCTTCAAACACCTTTTGGAGTCGCTCAAAAACTTAAAACGTAATGGTTGGATGACAGTTGCGGCTGT
TTCATCAGTAACAATTACTTTAGTTTTAGTTGGACTTTTCCTTTCAGTTATCTTGAATACTTCAAAAATATCTAATGGGA
TTGAAAACAATGTTCGGATTGTTGCCTACATGAAATTAGATGTTCATGATCAAGAGACAAAAATTCAAGATCCAAAAGAT
AATAAAAAAACAATCAATAATCCTGACCACCTGAAGATTTACGATTCAATCAAAAAAGTTCCTAATGTAAAAACAGTTGA
ATTCTCAAGTAAAGAAGCTCAGTTGAAAGAACTGACAAAGGCCTTAGGAAATAACTGGAATCTCTTTAAAGGTGATGCCA
ATCCACTTTACGATGCTTATATTGTTGAAGCTGATAAACCAGCAAATGTAAAATCAGTCACTTCAAAAATATCAAAACTT
TCAGGAATTGAAAAAGCTACTTATGGTGGTGCAAATACTGCAAAACTTTTCCAAATTGCTCAGGGAATTCGAACTTGGGG
AACTGCAGCGGCTATTCTGTTAATTTTCGTTGCTGTCTTCTTGATTTCTAACACCATTCGAATTACTATCCTATCAAGAC
AACGTGAAATTCAAATTATGCGTCTGGTTGGGGCTAAAAATGGTTATATCCGTTGGCCTTTCTTCTTGGAAGGCGCTTGG
GTTGGACTTTTAGGTTCAATTATTCCAGGACTTATTGTTGCTTGGGCTTATCGTCTTGCTTTTGTTAGCTTGACACCAAG
TCTTCAGTCACAAAAACTTGCAATGTTTGCTCCTAAAGAGTTCATTCCTGCAATAGTTGGATTGATGGCCGTGATTGGTA
TTTTGATTGGTTCATTTGGAGCCCTCTTATCAATGCGTCGTTTCCTTAAAATTTAA

Upstream 100 bases:

>100_bases
ACCCACAATAGCCAAATCGTTAACACTTTAAAACATCGTGTTATCGCAATTGAAAACGGACGAATTGTCCGCGACCAAGA
GGAAGGAGTTTACGGCTACG

Downstream 100 bases:

>100_bases
TAAAAATAAAAGAGAAGTTAAATCTTCTCTTTTTTTGCTAAAAAAAGCTGTCAGTAAATAAGTTTTTACTTATTTACTGA
CAGACTCTTAAATTTGTTTA

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MIRNFFKHLLESLKNLKRNGWMTVAAVSSVTITLVLVGLFLSVILNTSKISNGIENNVRIVAYMKLDVHDQETKIQDPKD
NKKTINNPDHLKIYDSIKKVPNVKTVEFSSKEAQLKELTKALGNNWNLFKGDANPLYDAYIVEADKPANVKSVTSKISKL
SGIEKATYGGANTAKLFQIAQGIRTWGTAAAILLIFVAVFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFFLEGAW
VGLLGSIIPGLIVAWAYRLAFVSLTPSLQSQKLAMFAPKEFIPAIVGLMAVIGILIGSFGALLSMRRFLKI

Sequences:

>Translated_311_residues
MIRNFFKHLLESLKNLKRNGWMTVAAVSSVTITLVLVGLFLSVILNTSKISNGIENNVRIVAYMKLDVHDQETKIQDPKD
NKKTINNPDHLKIYDSIKKVPNVKTVEFSSKEAQLKELTKALGNNWNLFKGDANPLYDAYIVEADKPANVKSVTSKISKL
SGIEKATYGGANTAKLFQIAQGIRTWGTAAAILLIFVAVFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFFLEGAW
VGLLGSIIPGLIVAWAYRLAFVSLTPSLQSQKLAMFAPKEFIPAIVGLMAVIGILIGSFGALLSMRRFLKI
>Mature_311_residues
MIRNFFKHLLESLKNLKRNGWMTVAAVSSVTITLVLVGLFLSVILNTSKISNGIENNVRIVAYMKLDVHDQETKIQDPKD
NKKTINNPDHLKIYDSIKKVPNVKTVEFSSKEAQLKELTKALGNNWNLFKGDANPLYDAYIVEADKPANVKSVTSKISKL
SGIEKATYGGANTAKLFQIAQGIRTWGTAAAILLIFVAVFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFFLEGAW
VGLLGSIIPGLIVAWAYRLAFVSLTPSLQSQKLAMFAPKEFIPAIVGLMAVIGILIGSFGALLSMRRFLKI

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=245, Percent_Identity=23.265306122449, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 34493; Mature: 34493

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRNFFKHLLESLKNLKRNGWMTVAAVSSVTITLVLVGLFLSVILNTSKISNGIENNVRI
CCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VAYMKLDVHDQETKIQDPKDNKKTINNPDHLKIYDSIKKVPNVKTVEFSSKEAQLKELTK
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHH
ALGNNWNLFKGDANPLYDAYIVEADKPANVKSVTSKISKLSGIEKATYGGANTAKLFQIA
HHCCCCCEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHH
QGIRTWGTAAAILLIFVAVFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFFLEGAW
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEEECCCEECHHH
VGLLGSIIPGLIVAWAYRLAFVSLTPSLQSQKLAMFAPKEFIPAIVGLMAVIGILIGSFG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ALLSMRRFLKI
HHHHHHHHHCC
>Mature Secondary Structure
MIRNFFKHLLESLKNLKRNGWMTVAAVSSVTITLVLVGLFLSVILNTSKISNGIENNVRI
CCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VAYMKLDVHDQETKIQDPKDNKKTINNPDHLKIYDSIKKVPNVKTVEFSSKEAQLKELTK
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHH
ALGNNWNLFKGDANPLYDAYIVEADKPANVKSVTSKISKLSGIEKATYGGANTAKLFQIA
HHCCCCCEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHH
QGIRTWGTAAAILLIFVAVFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFFLEGAW
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEEECCCEECHHH
VGLLGSIIPGLIVAWAYRLAFVSLTPSLQSQKLAMFAPKEFIPAIVGLMAVIGILIGSFG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ALLSMRRFLKI
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]