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The map label for this gene is choS

Identifier: 15672830

GI number: 15672830

Start: 865923

End: 867425

Strand: Direct

Name: choS

Synonym: L65675

Alternate gene names: 15672830

Gene position: 865923-867425 (Clockwise)

Preceding gene: 15672829

Following gene: 30024010

Centisome position: 36.6

GC content: 34.2

Gene sequence:

>1503_bases
ATGAATCAGCTAATTTCAACTTTTCAAAGCCAGCAAGGCCAATTTTGGCAGGCGCTTTTAGAACATATCCAGATTTCATT
AATTTCAATTTTTATTGCAATTCTGATTTCGATTCCTTTAGCTTTATTGTTACGACGTCTTCCCAAAATTGCTGAACCAG
TTTTGCAAGTCACCGGAATTTTTCAAACTATACCTAGTTTGGCACTGCTAGGACTCTTGATTCCATTCATCGGAATCGGA
AGTTTACCAGCAATTGTCGCTCTTGTTGTTTATGCGATTTTCCCTATTGTTCAAAATACTTATACTGGTTTAGAGCAAAT
TGAACCTTCTTTAATCGAAGCTGCAACAGCATTTGGGATGAATCGAAGAGAACGATTGATGAAATTTGAGCTCTCATTAG
CGATGCACTTTATCATGGCAGGAATTCGGACGAGTACAGTTATGGTCATTGGTACCGCAACACTAGCTGCTTTGATTGGT
GCTGGAGGCTTAGGGAACTTTATTCTGCTCGGAATCAATATGAATGATGTTTCATTGATTTTAATTGGAGCAATTTCATC
AGCACTATTAGCGATTATTTTCAGTAGTCTTTTAAAATTTTTAGAAAAAGCCAAGATAAAAACAATTCTCATCAGTTTTT
TCATTGGCTTACTCGTTCTTGGAGGCTCTTATTATCGACCTCAAACTTCTAATCATCCACAAATTACAATTGCTGGTAAA
TTGGGAGCAGAACCTGATGTTTTGATTAACATGTATAAACTAATGATTGAAAAAGATAGTAATATTCGCGTGAACTTAAA
ATCTAATTTTGGTGATACCACTTTCTTATATAATGCTTTGAAAGCTGGAAAAATTGATTTATATCCTGAATTCACAGGAA
CCATTACTTCAACATTTTTGAAAGATCCAGTGAGTTCAACTGATCCTAATGTCGTTTGGCAAAAGGCAGAAGAAGGAATA
AAAAAACTTAATCAATTTACATATCTGTCCCCAATGAAATTTCAAGATACATATGCAATTGCCGTCAAATCTGATTTTGC
TAAAGAGCATCAGCTCACCAAAATTTCTGATTTAGCGAATGTTTCAGGTTTAACTGCAGGCTTTGACGTTGAGTTTGCTA
ATCGTTCAGATGGAAATATTGGTTTGAGAAAGCTTTATGGTCTTGATTTAAATGTCAAAACCATGCAAAATAGTTTAATT
TATAAAGCACTAAATTCTGGTGCTGTGAATGTCGCTGAGGTTTATTCTACTGATAGTCAAATCAAGCAATATAATCTGAC
TGTCCTGAAAGATGATAAAAATCTTTTCCCACCTTACCAAGCAGCACCATTGATGAAAGAAAGTTTATTAAAAAAATATC
CTGAACTCAAAAAGATTCTCAATAAACTGTCAGGAAAAATTACTGACCAAGAGATGATTGAGATGAATTATGATGTTAAT
GTCAAACAAGAAGATGCTGCGAAAGTAGCAGAAAGATATTTAAAATCTAAAGGATTGATTTAA

Upstream 100 bases:

>100_bases
CGGAAATAATTAATCGTCTTTCTGATAAGGAAGTTTTAAAATACAAGGGCAAGTCAATTTCCTCAGATGATATTATATGC
TATATCGCAGGAGGTGACAA

Downstream 100 bases:

>100_bases
AAGAAAAAGTCATTTTATAATGGCTTTTTTGCTTTAGATGATAAGAAAATCTAAAAGAGCGTGTAAAAGTGCAAGAATAT
GATGTTTTGGTGCTTTAGTG

Product: choline ABC transporter permease and substrate binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MNQLISTFQSQQGQFWQALLEHIQISLISIFIAILISIPLALLLRRLPKIAEPVLQVTGIFQTIPSLALLGLLIPFIGIG
SLPAIVALVVYAIFPIVQNTYTGLEQIEPSLIEAATAFGMNRRERLMKFELSLAMHFIMAGIRTSTVMVIGTATLAALIG
AGGLGNFILLGINMNDVSLILIGAISSALLAIIFSSLLKFLEKAKIKTILISFFIGLLVLGGSYYRPQTSNHPQITIAGK
LGAEPDVLINMYKLMIEKDSNIRVNLKSNFGDTTFLYNALKAGKIDLYPEFTGTITSTFLKDPVSSTDPNVVWQKAEEGI
KKLNQFTYLSPMKFQDTYAIAVKSDFAKEHQLTKISDLANVSGLTAGFDVEFANRSDGNIGLRKLYGLDLNVKTMQNSLI
YKALNSGAVNVAEVYSTDSQIKQYNLTVLKDDKNLFPPYQAAPLMKESLLKKYPELKKILNKLSGKITDQEMIEMNYDVN
VKQEDAAKVAERYLKSKGLI

Sequences:

>Translated_500_residues
MNQLISTFQSQQGQFWQALLEHIQISLISIFIAILISIPLALLLRRLPKIAEPVLQVTGIFQTIPSLALLGLLIPFIGIG
SLPAIVALVVYAIFPIVQNTYTGLEQIEPSLIEAATAFGMNRRERLMKFELSLAMHFIMAGIRTSTVMVIGTATLAALIG
AGGLGNFILLGINMNDVSLILIGAISSALLAIIFSSLLKFLEKAKIKTILISFFIGLLVLGGSYYRPQTSNHPQITIAGK
LGAEPDVLINMYKLMIEKDSNIRVNLKSNFGDTTFLYNALKAGKIDLYPEFTGTITSTFLKDPVSSTDPNVVWQKAEEGI
KKLNQFTYLSPMKFQDTYAIAVKSDFAKEHQLTKISDLANVSGLTAGFDVEFANRSDGNIGLRKLYGLDLNVKTMQNSLI
YKALNSGAVNVAEVYSTDSQIKQYNLTVLKDDKNLFPPYQAAPLMKESLLKKYPELKKILNKLSGKITDQEMIEMNYDVN
VKQEDAAKVAERYLKSKGLI
>Mature_500_residues
MNQLISTFQSQQGQFWQALLEHIQISLISIFIAILISIPLALLLRRLPKIAEPVLQVTGIFQTIPSLALLGLLIPFIGIG
SLPAIVALVVYAIFPIVQNTYTGLEQIEPSLIEAATAFGMNRRERLMKFELSLAMHFIMAGIRTSTVMVIGTATLAALIG
AGGLGNFILLGINMNDVSLILIGAISSALLAIIFSSLLKFLEKAKIKTILISFFIGLLVLGGSYYRPQTSNHPQITIAGK
LGAEPDVLINMYKLMIEKDSNIRVNLKSNFGDTTFLYNALKAGKIDLYPEFTGTITSTFLKDPVSSTDPNVVWQKAEEGI
KKLNQFTYLSPMKFQDTYAIAVKSDFAKEHQLTKISDLANVSGLTAGFDVEFANRSDGNIGLRKLYGLDLNVKTMQNSLI
YKALNSGAVNVAEVYSTDSQIKQYNLTVLKDDKNLFPPYQAAPLMKESLLKKYPELKKILNKLSGKITDQEMIEMNYDVN
VKQEDAAKVAERYLKSKGLI

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788452, Length=308, Percent_Identity=28.2467532467532, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788449, Length=197, Percent_Identity=38.0710659898477, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788451, Length=214, Percent_Identity=31.3084112149533, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789033, Length=171, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 55147; Mature: 55147

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLISTFQSQQGQFWQALLEHIQISLISIFIAILISIPLALLLRRLPKIAEPVLQVTGI
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQTIPSLALLGLLIPFIGIGSLPAIVALVVYAIFPIVQNTYTGLEQIEPSLIEAATAFGM
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHCC
NRRERLMKFELSLAMHFIMAGIRTSTVMVIGTATLAALIGAGGLGNFILLGINMNDVSLI
CHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
LIGAISSALLAIIFSSLLKFLEKAKIKTILISFFIGLLVLGGSYYRPQTSNHPQITIAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEC
LGAEPDVLINMYKLMIEKDSNIRVNLKSNFGDTTFLYNALKAGKIDLYPEFTGTITSTFL
CCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHH
KDPVSSTDPNVVWQKAEEGIKKLNQFTYLSPMKFQDTYAIAVKSDFAKEHQLTKISDLAN
HCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
VSGLTAGFDVEFANRSDGNIGLRKLYGLDLNVKTMQNSLIYKALNSGAVNVAEVYSTDSQ
CCCCCCCCEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCHHH
IKQYNLTVLKDDKNLFPPYQAAPLMKESLLKKYPELKKILNKLSGKITDQEMIEMNYDVN
HHHEEEEEEECCCCCCCCHHCCHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHCCCCCC
VKQEDAAKVAERYLKSKGLI
CCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNQLISTFQSQQGQFWQALLEHIQISLISIFIAILISIPLALLLRRLPKIAEPVLQVTGI
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQTIPSLALLGLLIPFIGIGSLPAIVALVVYAIFPIVQNTYTGLEQIEPSLIEAATAFGM
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHCC
NRRERLMKFELSLAMHFIMAGIRTSTVMVIGTATLAALIGAGGLGNFILLGINMNDVSLI
CHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHHHHHHHCCCCCCCEEEEEECCCCHHHH
LIGAISSALLAIIFSSLLKFLEKAKIKTILISFFIGLLVLGGSYYRPQTSNHPQITIAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEC
LGAEPDVLINMYKLMIEKDSNIRVNLKSNFGDTTFLYNALKAGKIDLYPEFTGTITSTFL
CCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEECCCCCHHHHHHHH
KDPVSSTDPNVVWQKAEEGIKKLNQFTYLSPMKFQDTYAIAVKSDFAKEHQLTKISDLAN
HCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
VSGLTAGFDVEFANRSDGNIGLRKLYGLDLNVKTMQNSLIYKALNSGAVNVAEVYSTDSQ
CCCCCCCCEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCHHH
IKQYNLTVLKDDKNLFPPYQAAPLMKESLLKKYPELKKILNKLSGKITDQEMIEMNYDVN
HHHEEEEEEECCCCCCCCHHCCHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHCCCCCC
VKQEDAAKVAERYLKSKGLI
CCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]