Click here to switch to the map view.

The map label for this gene is acpS

Identifier: 15672825

GI number: 15672825

Start: 861387

End: 861746

Strand: Direct

Name: acpS

Synonym: L61355

Alternate gene names: 15672825

Gene position: 861387-861746 (Clockwise)

Preceding gene: 15672824

Following gene: 15672826

Centisome position: 36.41

GC content: 36.67

Gene sequence:

>360_bases
ATGGTTTTTGGAACAGGTGTTGATAATGTAGAGCTTTCTCGAATTCAAAAAGCACTGACACGTTCTGAACGTTTTGTGGA
ACAGGTTCTTACGGCAGTGGAGTTAGAAAAATATAATAGTTTTCAATCTACAGCTCGTAAAACTGAATTTCTTGCGGGAC
GTTGGGCAGCAAAAGAAGCTTTTTCTAAAGCTTACGGTACGGGATTTGGTAAGGCTTTGGGCATGCATGACCTTGAAATC
AAAAATGATGAATTAGGAAAACCCTTTTTTACTAAACATCCTTTTGATGGACAGGTTCATTTATCTATCTCGCATAGTAA
TTTAGAAGCTGTTGCTTTTGTTGTTTTGGAAAAGAATTAA

Upstream 100 bases:

>100_bases
TATAAAATTAAAGAGTTTAGTGACTAAACTTTTAAGGGTTTAAAAATCTGGCATAATTTGCCAGATTTTAACCTTTTATT
CCATAAATAGAGGTGGAAAA

Downstream 100 bases:

>100_bases
GAAGTAATAAAAATTTTTGCTTAAACTAGAGGAAGGTTTAAAAGATGAAAACTTCTCCACATCGCAATACGTCAGCCATT
GTTGACTTAAAGGCGATTAG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MVFGTGVDNVELSRIQKALTRSERFVEQVLTAVELEKYNSFQSTARKTEFLAGRWAAKEAFSKAYGTGFGKALGMHDLEI
KNDELGKPFFTKHPFDGQVHLSISHSNLEAVAFVVLEKN

Sequences:

>Translated_119_residues
MVFGTGVDNVELSRIQKALTRSERFVEQVLTAVELEKYNSFQSTARKTEFLAGRWAAKEAFSKAYGTGFGKALGMHDLEI
KNDELGKPFFTKHPFDGQVHLSISHSNLEAVAFVVLEKN
>Mature_119_residues
MVFGTGVDNVELSRIQKALTRSERFVEQVLTAVELEKYNSFQSTARKTEFLAGRWAAKEAFSKAYGTGFGKALGMHDLEI
KNDELGKPFFTKHPFDGQVHLSISHSNLEAVAFVVLEKN

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=88, Percent_Identity=40.9090909090909, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_LACLA (Q9CH95)

Other databases:

- EMBL:   AE005176
- PIR:   C86730
- RefSeq:   NP_266999.1
- ProteinModelPortal:   Q9CH95
- SMR:   Q9CH95
- GeneID:   1114471
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L61355
- NMPDR:   fig|272623.1.peg.863
- HOGENOM:   HBG734479
- OMA:   VHVSITH
- ProtClustDB:   PRK00070
- BioCyc:   LLAC272623:L61355-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13309; Mature: 13309

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFGTGVDNVELSRIQKALTRSERFVEQVLTAVELEKYNSFQSTARKTEFLAGRWAAKEA
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSKAYGTGFGKALGMHDLEIKNDELGKPFFTKHPFDGQVHLSISHSNLEAVAFVVLEKN
HHHHHCCCCHHHCCCCCCEECCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEECC
>Mature Secondary Structure
MVFGTGVDNVELSRIQKALTRSERFVEQVLTAVELEKYNSFQSTARKTEFLAGRWAAKEA
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSKAYGTGFGKALGMHDLEIKNDELGKPFFTKHPFDGQVHLSISHSNLEAVAFVVLEKN
HHHHHCCCCHHHCCCCCCEECCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471