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The map label for this gene is fabF

Identifier: 15672757

GI number: 15672757

Start: 784656

End: 785885

Strand: Direct

Name: fabF

Synonym: L0186

Alternate gene names: 15672757

Gene position: 784656-785885 (Clockwise)

Preceding gene: 15672756

Following gene: 15672758

Centisome position: 33.17

GC content: 40.98

Gene sequence:

>1230_bases
ATGACAAATAGAGTTGTTATCTCTGGTTATGGTGTAGTTAGTGCAATTGGAAATAGCCCAGAAGAATTTTGGAACAATCT
TAAAGCTGGTAAAACTGGAATTGGTCCAATCACTCACTTTGATGCTGAAGCAACAGGGATTTCTGTTGCAGCAGAAGTAA
AAGAATTTCCATTTGATAAATATTTCCAGAAAAAAGATGCACGACGCATGGATACTTTCTCACTTTATGCGGTTTATGCA
GCACTTGATGCAATGGAAATGTCTGGTATTACAGAAGAAAATACTAATTTTGACCGTTTGGGCTGTATCATGGCTTCTGG
GATTGGTGGACTTGAACAATCACAAAAAAATTCACAAGCAATTGTCGCTAAAGGCCCTCGTAAAGGGGTAGCACCACTCT
ACGTTCCACTTGCTATTGCTAATATGGCAACTGGTAACGTTGCTTTACGTACAGGTGCTCGTGGGGTTTCGCGTGCTGAA
GTAACGGCTTGTGCGGCTGGTGCTAATTCAATTGGTTCAGCTTTCCGTGAAATCAAACATGGTTACGCTGATGCAATGAT
TGCTGGTGGTGCTGAAGCGGCTATTTGTGAACTTGGAATTGCAGGTTTTGCTAATTTGACTGCTTTGACTAAAGAAACTG
ACCCTGAAAAAGCATGTATTCCATTCGATAAAAATCGTTCAGGATTTGTAATGGGCGAAGGTTCTGGTGTATTGATTTTG
GAAAGCCTTGAACATGCACAAGCTCGTGGCGCTAATATCTTGGCTGAGATTGTTGGATACGGAAATACAAATGATGCTTT
CCATATGACAACTCCTTCAGGAGTGGGTGCTGAAAATGCGATTAAATTGGCTTTGGAAGAAGCTGGTGCAAGTCCAGCTG
ATGTTGATTACGTTAATGCACACGGAACTTCAACACATGCCAATGAAGAAACTGAAAGCAAAGCAATTCACAATGTAATT
GGCGATAAAGCTTATGTTTCATCTACAAAAGCATTGCACGGTCATGCACTTGGTGCAACAGGTGCAATTGAAGCAGTGGC
AACTGTTCAAGCACTTTTGAATCAATATGCACCAGTAAATGCTGGAACAACTGAACTTGATGAAGGAATGACAATTAATG
TTGTTCTTGGTGAAGGTAAACCTGCTGATATTAATCTTGCATTGTCGCAAGACTTTGGTTTCGGTGGACACAATGCTGTA
TTGGCATTCAAGAAATGGACTGGAGAGTAA

Upstream 100 bases:

>100_bases
GCTGAACAAGAATATATGACTGGACAAGTACTTACCATTGATGGTGGAGTTTCAATGTAAATTATTCATTGATAAATTTT
AAAATTAAGAGGATAAAAAT

Downstream 100 bases:

>100_bases
ATAAAAATGAACATTTCAGAAGTAAAAGATTTGATGAACCAATTCAATGGTTCTACTTTACGTGAATTTTCTTGGAAAAA
TGCTGATGGTGAATTATCAT

Product: 3-oxoacyl-[acyl-carrier-protein] synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTNRVVISGYGVVSAIGNSPEEFWNNLKAGKTGIGPITHFDAEATGISVAAEVKEFPFDKYFQKKDARRMDTFSLYAVYA
ALDAMEMSGITEENTNFDRLGCIMASGIGGLEQSQKNSQAIVAKGPRKGVAPLYVPLAIANMATGNVALRTGARGVSRAE
VTACAAGANSIGSAFREIKHGYADAMIAGGAEAAICELGIAGFANLTALTKETDPEKACIPFDKNRSGFVMGEGSGVLIL
ESLEHAQARGANILAEIVGYGNTNDAFHMTTPSGVGAENAIKLALEEAGASPADVDYVNAHGTSTHANEETESKAIHNVI
GDKAYVSSTKALHGHALGATGAIEAVATVQALLNQYAPVNAGTTELDEGMTINVVLGEGKPADINLALSQDFGFGGHNAV
LAFKKWTGE

Sequences:

>Translated_409_residues
MTNRVVISGYGVVSAIGNSPEEFWNNLKAGKTGIGPITHFDAEATGISVAAEVKEFPFDKYFQKKDARRMDTFSLYAVYA
ALDAMEMSGITEENTNFDRLGCIMASGIGGLEQSQKNSQAIVAKGPRKGVAPLYVPLAIANMATGNVALRTGARGVSRAE
VTACAAGANSIGSAFREIKHGYADAMIAGGAEAAICELGIAGFANLTALTKETDPEKACIPFDKNRSGFVMGEGSGVLIL
ESLEHAQARGANILAEIVGYGNTNDAFHMTTPSGVGAENAIKLALEEAGASPADVDYVNAHGTSTHANEETESKAIHNVI
GDKAYVSSTKALHGHALGATGAIEAVATVQALLNQYAPVNAGTTELDEGMTINVVLGEGKPADINLALSQDFGFGGHNAV
LAFKKWTGE
>Mature_408_residues
TNRVVISGYGVVSAIGNSPEEFWNNLKAGKTGIGPITHFDAEATGISVAAEVKEFPFDKYFQKKDARRMDTFSLYAVYAA
LDAMEMSGITEENTNFDRLGCIMASGIGGLEQSQKNSQAIVAKGPRKGVAPLYVPLAIANMATGNVALRTGARGVSRAEV
TACAAGANSIGSAFREIKHGYADAMIAGGAEAAICELGIAGFANLTALTKETDPEKACIPFDKNRSGFVMGEGSGVLILE
SLEHAQARGANILAEIVGYGNTNDAFHMTTPSGVGAENAIKLALEEAGASPADVDYVNAHGTSTHANEETESKAIHNVIG
DKAYVSSTKALHGHALGATGAIEAVATVQALLNQYAPVNAGTTELDEGMTINVVLGEGKPADINLALSQDFGFGGHNAVL
AFKKWTGE

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=419, Percent_Identity=38.4248210023866, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI223972627, Length=417, Percent_Identity=28.2973621103118, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI41872631, Length=361, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787337, Length=412, Percent_Identity=42.9611650485437, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1788663, Length=409, Percent_Identity=36.4303178484108, Blast_Score=205, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI71983541, Length=414, Percent_Identity=35.024154589372, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI71983535, Length=261, Percent_Identity=40.6130268199234, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI212642053, Length=363, Percent_Identity=24.2424242424242, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17550940, Length=413, Percent_Identity=24.455205811138, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320904, Length=450, Percent_Identity=37.1111111111111, Blast_Score=270, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24644341, Length=431, Percent_Identity=39.4431554524362, Blast_Score=264, Evalue=7e-71,
Organism=Drosophila melanogaster, GI221330659, Length=276, Percent_Identity=26.8115942028986, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19920632, Length=276, Percent_Identity=26.8115942028986, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42474; Mature: 42343

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRVVISGYGVVSAIGNSPEEFWNNLKAGKTGIGPITHFDAEATGISVAAEVKEFPFDK
CCCCEEEECCCCEECCCCCHHHHHHHHHCCCCCCCCCEECCCCCCCEEEEHHHHHCCCHH
YFQKKDARRMDTFSLYAVYAALDAMEMSGITEENTNFDRLGCIMASGIGGLEQSQKNSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCE
IVAKGPRKGVAPLYVPLAIANMATGNVALRTGARGVSRAEVTACAAGANSIGSAFREIKH
EEEECCCCCCCCEEHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
GYADAMIAGGAEAAICELGIAGFANLTALTKETDPEKACIPFDKNRSGFVMGEGSGVLIL
HHHHHEECCCCCHHHHHHCCCCHHHHEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEE
ESLEHAQARGANILAEIVGYGNTNDAFHMTTPSGVGAENAIKLALEEAGASPADVDYVNA
ECHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHEEEHHHCCCCCCCCEEEEC
HGTSTHANEETESKAIHNVIGDKAYVSSTKALHGHALGATGAIEAVATVQALLNQYAPVN
CCCCCCCCCHHHHHHHHHHHCCHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCC
AGTTELDEGMTINVVLGEGKPADINLALSQDFGFGGHNAVLAFKKWTGE
CCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
TNRVVISGYGVVSAIGNSPEEFWNNLKAGKTGIGPITHFDAEATGISVAAEVKEFPFDK
CCCEEEECCCCEECCCCCHHHHHHHHHCCCCCCCCCEECCCCCCCEEEEHHHHHCCCHH
YFQKKDARRMDTFSLYAVYAALDAMEMSGITEENTNFDRLGCIMASGIGGLEQSQKNSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCE
IVAKGPRKGVAPLYVPLAIANMATGNVALRTGARGVSRAEVTACAAGANSIGSAFREIKH
EEEECCCCCCCCEEHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
GYADAMIAGGAEAAICELGIAGFANLTALTKETDPEKACIPFDKNRSGFVMGEGSGVLIL
HHHHHEECCCCCHHHHHHCCCCHHHHEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEE
ESLEHAQARGANILAEIVGYGNTNDAFHMTTPSGVGAENAIKLALEEAGASPADVDYVNA
ECHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHEEEHHHCCCCCCCCEEEEC
HGTSTHANEETESKAIHNVIGDKAYVSSTKALHGHALGATGAIEAVATVQALLNQYAPVN
CCCCCCCCCHHHHHHHHHHHCCHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCC
AGTTELDEGMTINVVLGEGKPADINLALSQDFGFGGHNAVLAFKKWTGE
CCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]