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The map label for this gene is fabD

Identifier: 15672755

GI number: 15672755

Start: 782872

End: 783798

Strand: Direct

Name: fabD

Synonym: L0184

Alternate gene names: 15672755

Gene position: 782872-783798 (Clockwise)

Preceding gene: 15672754

Following gene: 15672756

Centisome position: 33.09

GC content: 37.0

Gene sequence:

>927_bases
ATGACTAAAACAGCATTTTTATTCTCAGGTCAAGGGGCACAAAAGCTTGGAATGGCACGTGACTTATATGACCAATATGA
AACAGTTAAAGCAACTTTTGATGAAGCAAGTCAAGCTTTAGGATATGATTTGCGAGCTTTGATTGATAATGATGAAGAAA
AACTAAATGAAACAAAGTACACTCAACCTGCAATTTTAACAACCTCTGTTGCTATTTTACGTTTGTTAAGTGAGAATGGG
ATTAAACCTGACCTTGTTGCTGGTCTTAGTCTTGGTGAATATTCTGCCTTGGTAGCATCAGGAATCATTGATTTTCAAGA
AGCAGTTAAGCTTGTAGCTAAACGTGGTCAATATATGACAGAAGCTGCACCGACTGGTTCTGGTAAAATGGTCGCTGTAA
TGAACACAGACCCAGCCTTGATTGAAGAAATTTGCCAGAAAGCGGCCGAATTTAAAGGCGGTATTGTGAGTCCAGCAAAT
TATAACACGCCCGCACAAATTGTTATTGGTGGTGAAGTTGAGGCGGTTGATTATGCTGTTGAGTTGCTAAAAGAAGCCGG
AGTTCGTAAACTTATTGAATTAAAAGTTTCAGGACCTTTCCATACAGCAATTTTAAAACCAGCATCTGAAAAATTGGCTT
TGGAGCTTGATAAAATTGATTTTAGACCTTTTGAATTACCATTAATCTCAAATACGAGTGCTAAAGTAATGGAAAATGAT
GAAGTCAAAGGACTTTTGACGCGTCAAGTCATGGAACCAGTTCGTTTTTATGAATCGGTTGAAACAATGCAAAAACTAGG
GGCGACTCGCTTTATTGAAGTTGGTCCTGGGAGAGTACTTTCAGGTTTCATTAAAAAAATTGATAAAAATGCAGAAATTG
CTAATGTTGAAAATTTAGCTTCATTTGAAGCTTTGATTAATCAGTAA

Upstream 100 bases:

>100_bases
CATTTTACAATACTAATAATTAACTTTATAAAAGAAAATACGAGGAATTCTAATTGACTGATTTTGAATCATTGATTCAA
AAGGTTGATTACTATATATT

Downstream 100 bases:

>100_bases
AATTGAAGAAAGGAATTGTGTTTATCCTTTTGAAATCTTAGTACTAAAGTGCTAAAACTTCTTAGGCGGGCTCATATCTT
AAATAATGGAAATTAAAAAT

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTKTAFLFSGQGAQKLGMARDLYDQYETVKATFDEASQALGYDLRALIDNDEEKLNETKYTQPAILTTSVAILRLLSENG
IKPDLVAGLSLGEYSALVASGIIDFQEAVKLVAKRGQYMTEAAPTGSGKMVAVMNTDPALIEEICQKAAEFKGGIVSPAN
YNTPAQIVIGGEVEAVDYAVELLKEAGVRKLIELKVSGPFHTAILKPASEKLALELDKIDFRPFELPLISNTSAKVMEND
EVKGLLTRQVMEPVRFYESVETMQKLGATRFIEVGPGRVLSGFIKKIDKNAEIANVENLASFEALINQ

Sequences:

>Translated_308_residues
MTKTAFLFSGQGAQKLGMARDLYDQYETVKATFDEASQALGYDLRALIDNDEEKLNETKYTQPAILTTSVAILRLLSENG
IKPDLVAGLSLGEYSALVASGIIDFQEAVKLVAKRGQYMTEAAPTGSGKMVAVMNTDPALIEEICQKAAEFKGGIVSPAN
YNTPAQIVIGGEVEAVDYAVELLKEAGVRKLIELKVSGPFHTAILKPASEKLALELDKIDFRPFELPLISNTSAKVMEND
EVKGLLTRQVMEPVRFYESVETMQKLGATRFIEVGPGRVLSGFIKKIDKNAEIANVENLASFEALINQ
>Mature_307_residues
TKTAFLFSGQGAQKLGMARDLYDQYETVKATFDEASQALGYDLRALIDNDEEKLNETKYTQPAILTTSVAILRLLSENGI
KPDLVAGLSLGEYSALVASGIIDFQEAVKLVAKRGQYMTEAAPTGSGKMVAVMNTDPALIEEICQKAAEFKGGIVSPANY
NTPAQIVIGGEVEAVDYAVELLKEAGVRKLIELKVSGPFHTAILKPASEKLALELDKIDFRPFELPLISNTSAKVMENDE
VKGLLTRQVMEPVRFYESVETMQKLGATRFIEVGPGRVLSGFIKKIDKNAEIANVENLASFEALINQ

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=309, Percent_Identity=32.0388349514563, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI41872631, Length=223, Percent_Identity=30.0448430493274, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787334, Length=290, Percent_Identity=48.2758620689655, Blast_Score=256, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71984332, Length=292, Percent_Identity=34.5890410958904, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17550940, Length=302, Percent_Identity=29.4701986754967, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24665753, Length=308, Percent_Identity=30.8441558441558, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33542; Mature: 33411

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTAFLFSGQGAQKLGMARDLYDQYETVKATFDEASQALGYDLRALIDNDEEKLNETKY
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHCC
TQPAILTTSVAILRLLSENGIKPDLVAGLSLGEYSALVASGIIDFQEAVKLVAKRGQYMT
CCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EAAPTGSGKMVAVMNTDPALIEEICQKAAEFKGGIVSPANYNTPAQIVIGGEVEAVDYAV
HCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHH
ELLKEAGVRKLIELKVSGPFHTAILKPASEKLALELDKIDFRPFELPLISNTSAKVMEND
HHHHHHCHHEEEEEEECCCCHHHHCCCCCHHHEEEEECCCCCCEECEEECCCCCHHHCCC
EVKGLLTRQVMEPVRFYESVETMQKLGATRFIEVGPGRVLSGFIKKIDKNAEIANVENLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCCHHHHH
SFEALINQ
HHHHHHCC
>Mature Secondary Structure 
TKTAFLFSGQGAQKLGMARDLYDQYETVKATFDEASQALGYDLRALIDNDEEKLNETKY
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHCC
TQPAILTTSVAILRLLSENGIKPDLVAGLSLGEYSALVASGIIDFQEAVKLVAKRGQYMT
CCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EAAPTGSGKMVAVMNTDPALIEEICQKAAEFKGGIVSPANYNTPAQIVIGGEVEAVDYAV
HCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHH
ELLKEAGVRKLIELKVSGPFHTAILKPASEKLALELDKIDFRPFELPLISNTSAKVMEND
HHHHHHCHHEEEEEEECCCCHHHHCCCCCHHHEEEEECCCCCCEECEEECCCCCHHHCCC
EVKGLLTRQVMEPVRFYESVETMQKLGATRFIEVGPGRVLSGFIKKIDKNAEIANVENLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCCHHHHH
SFEALINQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]