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The map label for this gene is dtpT

Identifier: 15672684

GI number: 15672684

Start: 704421

End: 705914

Strand: Direct

Name: dtpT

Synonym: L104437

Alternate gene names: 15672684

Gene position: 704421-705914 (Clockwise)

Preceding gene: 15672683

Following gene: 15672685

Centisome position: 29.78

GC content: 37.95

Gene sequence:

>1494_bases
ATGCAAAACTTAAACAAAACAGAAAAAACATTTTTCGGTCAACCTCGCGGCCTATTGACGCTTTTTCAGACTGAGTTCTG
GGAGCGTTTTTCTTACTATGGGATGCGTGCCATTCTGGTTTATTACCTCTATGCATTGACAACTGCTGACAACGCAGGTT
TAGGACTTCCTAAAGCTCAAGCAATGGCGATTGTAAGTATCTATGGTGCACTTGTCTATCTTTCAACAATTGTTGGAGGG
TGGGTTGCTGACCGCTTGTTGGGCGCTTCGCGCACAATCTTCCTTGGTGGAATTTTAATCACTTTGGGACACATCGCTTT
AGCAACACCATTTGGTTTATCTTCACTGTTCGTGGCATTATTCTTAATTATCTTGGGAACAGGGATGCTTAAACCGAATA
TTTCAAATATGGTTGGACATCTTTATTCTAAAGATGACTCACGTCGTGACACTGGATTCAATATCTTTGTTGTCGGAATT
AACATGGGTTCTCTGATTGCTCCATTGATTGTTGGGACAGTTGGACAAGGCGTGAATTATCACTTAGGATTCTCACTTGC
AGCTATCGGTATGATTTTTGCATTATTTGCTTATTGGTATGGACGTCTTCGTCACTTCCCAGAAATTGGACGCGAGCCTT
CAAATCCAATGGATTCAAAAGCAAGACGTAATTTTCTTATTACATTGACAATTGTTGTTATTGTCGCAATTATTGGTTTC
TTCTTACTTTATCAAGCAAGTCCAGCTAATTTCATTAATAACTTCATTAATGTTTTATCAATTATCGGTATTGTTGTTCC
AATTATTTATTTCGTAATGATGTTTACCTCTAAAAAGGTAGAATCAGATGAACGTCGTAAATTAACAGCATATATTCCTT
TGTTCCTTTCTGCTATTGTCTTTTGGGCAATTGAAGAACAAAGTTCTACAATTATTGCGGTTTGGGGAGAATCACGTTCT
AATTTGGACCCAACTTGGTTTGGAATTACTTTCCATATTGACCCTTCTTGGTATCAATTATTGAACCCGCTCTTCATCGT
TCTCTTGTCACCTATCTTTGTTCGTCTTTGGAATAAATTGGGTGAACGTCAACCTTCAACAATTGTAAAATTTGGTCTTG
GTTTGATGTTGACAGGGATTTCTTATTTGATTATGACACTTCCAGGTCTCTTGAACGGAACTTCAGGTCGTGCAAGTGCT
CTTTGGTTAGTATTGATGTTTGCTGTCCAAATGGCAGGTGAATTACTTGTTTCACCAGTTGGATTATCAGTTTCAACAAA
ATTAGCTCCAGTTGCTTTCCAATCACAAATGATGGCGATGTGGTTCTTGGCAGATTCAACTTCACAAGCAATCAATGCTC
AAATTACACCACTCTTTAAAGCAGCAACAGAAGTTCACTTCTTTGCGATTACTGGTATTATTGGTATTATCGTGGGAATT
ATCCTCCTTATTGTCAAAAAACCTATTTTGAAATTAATGGGAGATGTTCGTTAA

Upstream 100 bases:

>100_bases
TGTTATTGTCCCTCTTTTTCCCGCGTTTTTCAAAGAATCTGTATAGGCAAAATTGTTTGACAACTTGACAAGTTGTATAG
AAAACTTTATAATATAATCT

Downstream 100 bases:

>100_bases
TTAGTAATTAATAAAACCTATCTTTAATGATAGGTTTTTTGTATTTTAAAAACTATAGAAGTGTCTGAAAAGTTACACTT
GTTAAAAGTCTTTTACAAAT

Product: di-/tripeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MQNLNKTEKTFFGQPRGLLTLFQTEFWERFSYYGMRAILVYYLYALTTADNAGLGLPKAQAMAIVSIYGALVYLSTIVGG
WVADRLLGASRTIFLGGILITLGHIALATPFGLSSLFVALFLIILGTGMLKPNISNMVGHLYSKDDSRRDTGFNIFVVGI
NMGSLIAPLIVGTVGQGVNYHLGFSLAAIGMIFALFAYWYGRLRHFPEIGREPSNPMDSKARRNFLITLTIVVIVAIIGF
FLLYQASPANFINNFINVLSIIGIVVPIIYFVMMFTSKKVESDERRKLTAYIPLFLSAIVFWAIEEQSSTIIAVWGESRS
NLDPTWFGITFHIDPSWYQLLNPLFIVLLSPIFVRLWNKLGERQPSTIVKFGLGLMLTGISYLIMTLPGLLNGTSGRASA
LWLVLMFAVQMAGELLVSPVGLSVSTKLAPVAFQSQMMAMWFLADSTSQAINAQITPLFKAATEVHFFAITGIIGIIVGI
ILLIVKKPILKLMGDVR

Sequences:

>Translated_497_residues
MQNLNKTEKTFFGQPRGLLTLFQTEFWERFSYYGMRAILVYYLYALTTADNAGLGLPKAQAMAIVSIYGALVYLSTIVGG
WVADRLLGASRTIFLGGILITLGHIALATPFGLSSLFVALFLIILGTGMLKPNISNMVGHLYSKDDSRRDTGFNIFVVGI
NMGSLIAPLIVGTVGQGVNYHLGFSLAAIGMIFALFAYWYGRLRHFPEIGREPSNPMDSKARRNFLITLTIVVIVAIIGF
FLLYQASPANFINNFINVLSIIGIVVPIIYFVMMFTSKKVESDERRKLTAYIPLFLSAIVFWAIEEQSSTIIAVWGESRS
NLDPTWFGITFHIDPSWYQLLNPLFIVLLSPIFVRLWNKLGERQPSTIVKFGLGLMLTGISYLIMTLPGLLNGTSGRASA
LWLVLMFAVQMAGELLVSPVGLSVSTKLAPVAFQSQMMAMWFLADSTSQAINAQITPLFKAATEVHFFAITGIIGIIVGI
ILLIVKKPILKLMGDVR
>Mature_497_residues
MQNLNKTEKTFFGQPRGLLTLFQTEFWERFSYYGMRAILVYYLYALTTADNAGLGLPKAQAMAIVSIYGALVYLSTIVGG
WVADRLLGASRTIFLGGILITLGHIALATPFGLSSLFVALFLIILGTGMLKPNISNMVGHLYSKDDSRRDTGFNIFVVGI
NMGSLIAPLIVGTVGQGVNYHLGFSLAAIGMIFALFAYWYGRLRHFPEIGREPSNPMDSKARRNFLITLTIVVIVAIIGF
FLLYQASPANFINNFINVLSIIGIVVPIIYFVMMFTSKKVESDERRKLTAYIPLFLSAIVFWAIEEQSSTIIAVWGESRS
NLDPTWFGITFHIDPSWYQLLNPLFIVLLSPIFVRLWNKLGERQPSTIVKFGLGLMLTGISYLIMTLPGLLNGTSGRASA
LWLVLMFAVQMAGELLVSPVGLSVSTKLAPVAFQSQMMAMWFLADSTSQAINAQITPLFKAATEVHFFAITGIIGIIVGI
ILLIVKKPILKLMGDVR

Specific function: Proton-dependent uptake of di- or tri-peptides

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family

Homologues:

Organism=Homo sapiens, GI4827008, Length=219, Percent_Identity=32.8767123287671, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI226371746, Length=196, Percent_Identity=32.1428571428571, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI226371748, Length=187, Percent_Identity=30.4812834224599, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1787922, Length=456, Percent_Identity=27.1929824561404, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789911, Length=500, Percent_Identity=30.2, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1790572, Length=476, Percent_Identity=28.3613445378151, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1786927, Length=507, Percent_Identity=29.7830374753452, Blast_Score=172, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17569141, Length=369, Percent_Identity=27.10027100271, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71987453, Length=186, Percent_Identity=32.258064516129, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639581, Length=357, Percent_Identity=27.4509803921569, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24639585, Length=357, Percent_Identity=27.4509803921569, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24639583, Length=357, Percent_Identity=27.4509803921569, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28571102, Length=411, Percent_Identity=25.3041362530414, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571100, Length=411, Percent_Identity=25.3041362530414, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571098, Length=411, Percent_Identity=25.3041362530414, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTPT_LACLA (P0C2U2)

Other databases:

- EMBL:   AE005176
- PIR:   F86712
- RefSeq:   NP_266858.1
- ProteinModelPortal:   P0C2U2
- GeneID:   1114327
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L104437
- NMPDR:   fig|272623.1.peg.720
- HOGENOM:   HBG586603
- OMA:   QAINAQV
- ProtClustDB:   CLSK697360
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456
- PANTHER:   PTHR11654:SF6
- TIGRFAMs:   TIGR00924

Pfam domain/function: PF00854 PTR2; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 54845; Mature: 54845

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50850 MFS; PS01022 PTR2_1; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd1a66c4)-; HASH(0xd4b59a0)-; HASH(0xcffaef0)-; HASH(0xd84b534)-; HASH(0xb2395c8)-; HASH(0xd451b54)-; HASH(0xbf28cc4)-; HASH(0xcc3ad80)-; HASH(0xd41d4a0)-; HASH(0xd85d928)-; HASH(0xd4b2dd4)-; HASH(0xd84901c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLNKTEKTFFGQPRGLLTLFQTEFWERFSYYGMRAILVYYLYALTTADNAGLGLPKAQ
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
AMAIVSIYGALVYLSTIVGGWVADRLLGASRTIFLGGILITLGHIALATPFGLSSLFVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FLIILGTGMLKPNISNMVGHLYSKDDSRRDTGFNIFVVGINMGSLIAPLIVGTVGQGVNY
HHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCE
HLGFSLAAIGMIFALFAYWYGRLRHFPEIGREPSNPMDSKARRNFLITLTIVVIVAIIGF
EHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHH
FLLYQASPANFINNFINVLSIIGIVVPIIYFVMMFTSKKVESDERRKLTAYIPLFLSAIV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FWAIEEQSSTIIAVWGESRSNLDPTWFGITFHIDPSWYQLLNPLFIVLLSPIFVRLWNKL
HHHEECCCCEEEEEECCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
GERQPSTIVKFGLGLMLTGISYLIMTLPGLLNGTSGRASALWLVLMFAVQMAGELLVSPV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GLSVSTKLAPVAFQSQMMAMWFLADSTSQAINAQITPLFKAATEVHFFAITGIIGIIVGI
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ILLIVKKPILKLMGDVR
HHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MQNLNKTEKTFFGQPRGLLTLFQTEFWERFSYYGMRAILVYYLYALTTADNAGLGLPKAQ
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
AMAIVSIYGALVYLSTIVGGWVADRLLGASRTIFLGGILITLGHIALATPFGLSSLFVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FLIILGTGMLKPNISNMVGHLYSKDDSRRDTGFNIFVVGINMGSLIAPLIVGTVGQGVNY
HHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCE
HLGFSLAAIGMIFALFAYWYGRLRHFPEIGREPSNPMDSKARRNFLITLTIVVIVAIIGF
EHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHH
FLLYQASPANFINNFINVLSIIGIVVPIIYFVMMFTSKKVESDERRKLTAYIPLFLSAIV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FWAIEEQSSTIIAVWGESRSNLDPTWFGITFHIDPSWYQLLNPLFIVLLSPIFVRLWNKL
HHHEECCCCEEEEEECCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
GERQPSTIVKFGLGLMLTGISYLIMTLPGLLNGTSGRASALWLVLMFAVQMAGELLVSPV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GLSVSTKLAPVAFQSQMMAMWFLADSTSQAINAQITPLFKAATEVHFFAITGIIGIIVGI
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ILLIVKKPILKLMGDVR
HHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471