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The map label for this gene is sugE

Identifier: 15672104

GI number: 15672104

Start: 124677

End: 125030

Strand: Direct

Name: sugE

Synonym: L124677

Alternate gene names: 15672104

Gene position: 124677-125030 (Clockwise)

Preceding gene: 15672101

Following gene: 15672105

Centisome position: 5.27

GC content: 38.98

Gene sequence:

>354_bases
ATGGTCGTTCTTTTTTTAGCTGAGGAGGCAAAAATGACTTGGATTTATTTACTTATAGCGGGAACATTTGAAGTGGCTTG
GGCAACAACAATGAAGTTGAGCCACGGCTTTTCAAATTTGAAGTTTACACTACTGACAATCATCGGAATGATTGCTAGCT
TTGGTTTTCTTGCGCTAGCTCTAAAAAAATTACCTTTAGGGATTGCTTACCCAATTTGGACGGGGATCGGAGCCGTTGGC
TCAATCTTAATCGGACTTATTCTATTCAAAGATAAAATCCCACCATTAACTTGGCTTTTCATTGCCTGTTTAGTCGTGGG
TATTATTGGAATAAAAGTAACAAGCGGTCACTAA

Upstream 100 bases:

>100_bases
AAAAGTGTGATAGAATGAAGAAAATAGAATAAATACTCCACCGGGAGTTTAATCGTATGAACGATTATTTACATTTCAGT
AGGTCTGAGAAGAAATGTAG

Downstream 100 bases:

>100_bases
AGATGATACAGTCTTTTAATTTTTTAGTATATAGATTTCATGATATAATAAGAGAATTGGTAAAAAATAAAAGAAATAGC
AATAGAATAATCTATTTGCT

Product: SugE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MVVLFLAEEAKMTWIYLLIAGTFEVAWATTMKLSHGFSNLKFTLLTIIGMIASFGFLALALKKLPLGIAYPIWTGIGAVG
SILIGLILFKDKIPPLTWLFIACLVVGIIGIKVTSGH

Sequences:

>Translated_117_residues
MVVLFLAEEAKMTWIYLLIAGTFEVAWATTMKLSHGFSNLKFTLLTIIGMIASFGFLALALKKLPLGIAYPIWTGIGAVG
SILIGLILFKDKIPPLTWLFIACLVVGIIGIKVTSGH
>Mature_117_residues
MVVLFLAEEAKMTWIYLLIAGTFEVAWATTMKLSHGFSNLKFTLLTIIGMIASFGFLALALKKLPLGIAYPIWTGIGAVG
SILIGLILFKDKIPPLTWLFIACLVVGIIGIKVTSGH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=46.1538461538462, Blast_Score=98, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 12666; Mature: 12666

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVLFLAEEAKMTWIYLLIAGTFEVAWATTMKLSHGFSNLKFTLLTIIGMIASFGFLALA
CEEEEEECCCCHHEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LKKLPLGIAYPIWTGIGAVGSILIGLILFKDKIPPLTWLFIACLVVGIIGIKVTSGH
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MVVLFLAEEAKMTWIYLLIAGTFEVAWATTMKLSHGFSNLKFTLLTIIGMIASFGFLALA
CEEEEEECCCCHHEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LKKLPLGIAYPIWTGIGAVGSILIGLILFKDKIPPLTWLFIACLVVGIIGIKVTSGH
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]