Click here to switch to the map view.

The map label for this gene is araT

Identifier: 15672039

GI number: 15672039

Start: 56584

End: 57759

Strand: Direct

Name: araT

Synonym: L56488

Alternate gene names: 15672039

Gene position: 56584-57759 (Clockwise)

Preceding gene: 15672038

Following gene: 15672040

Centisome position: 2.39

GC content: 37.07

Gene sequence:

>1176_bases
ATGGATTTATTAAAAAAATTTAACCCTAATTTAGATAAAATTGAAATTTCATTGATTCGTCAGTTTGACCAACAGGTTTC
ATCTATTCCTGATGTTATTAAGTTGACTTTGGGAGAACCTGATTTTTATACGCCTGAGCATGTTAAACAAGCAGGGATTG
TGGCGATTGAAAATAATCAAAGTCATTATACTGGAATGGCTGGTTTACTAGAACTACGTCAGGCAGCTAGTGAATTTATG
AATAAAAAATATGGTTTATCTTATGCAGCAGAAGATGAAATTTTAGTTACTGTTGGAGTAACGGAAGCCATTTCTAGTGT
TTTGTTATCAATTTTGGTTGCTGGTGATGAAGTTTTGATTCCCGCGCCTGCATATCCTGGTTATGAGCCATTAATTACGC
TTGCTGGCGGTTCTTTGGTTGAAATTGATACAAGAGCTAATGATTTTGTTCTTACGCCTGAGATGCTTGAACAAGCGATT
GTCGAGCGTGAGGGAAAAGTTAAGGCCGTTATTTTGAATTATCCAGCAAATCCTACAGGGGTAACTTATAATCGGGGGCA
AATTAAGGCTTTAGCTGAAGTTTTGAAAAAGCATGAAGTATTTGTGATTGCTGATGAAGTTTATTCTGAACTAAATTATA
CTGACCAACCGCATGTGTCAATTGCTGAATATGCACCTGAGCAAACAATCGTTCTTAATGGTTTATCAAAATCGCATGCG
ATGACTGGTTGGCGGATTGGATTAATCTTTGCAGCGCGTGAATTAGTGGCACAGATTATTAAGACTCACCAATATTTGGT
GACTTCGGCTTCAACTCAGTCACAGTTTGCAGCGATTGAAGCTTTGAAAAATGGTGCTTATGATGCTCTTCCGATGAAAA
AAGAATATCTTAAACGTCGTGATTATATTATTGAAAAGATGTCAGACCTTGGTTTCAAAATTATTGAACCAGATGGAGCT
TTCTACATTTTTGCAAAAATTCCAGCTGATTTAGAACAAGATTCATTCAAATTTGCTGTGGATTTTGCAAAAGAAAATGC
AGTTGCCATTATTCCTGGTATCGCTTTTGGTCAGTACGGTGAAGGATTTGTCCGCTTATCTTATGCGGCTTCAATGGATA
TGATTGAGCAAGCAATGGCAAGATTGACGGATTATGTGACTAAAAAACGTGGCTGA

Upstream 100 bases:

>100_bases
CTGACAGAAATCTGTCAGTAAAGTAAATAGTCTGAAAATAGTGTATAATATTGTCAAAAGATTTCTGTCAGTAGAACAGG
ATGTAAGTAGAGGATGTTTT

Downstream 100 bases:

>100_bases
GCAATCGGTCAGTAAAATTAAAAATCATTGATAACAGTTAGAAGAGTTGTCAGTGATTTTTTTGATATAATGAAATAAAA
TATCGAAAGGAGAAAATCAT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MDLLKKFNPNLDKIEISLIRQFDQQVSSIPDVIKLTLGEPDFYTPEHVKQAGIVAIENNQSHYTGMAGLLELRQAASEFM
NKKYGLSYAAEDEILVTVGVTEAISSVLLSILVAGDEVLIPAPAYPGYEPLITLAGGSLVEIDTRANDFVLTPEMLEQAI
VEREGKVKAVILNYPANPTGVTYNRGQIKALAEVLKKHEVFVIADEVYSELNYTDQPHVSIAEYAPEQTIVLNGLSKSHA
MTGWRIGLIFAARELVAQIIKTHQYLVTSASTQSQFAAIEALKNGAYDALPMKKEYLKRRDYIIEKMSDLGFKIIEPDGA
FYIFAKIPADLEQDSFKFAVDFAKENAVAIIPGIAFGQYGEGFVRLSYAASMDMIEQAMARLTDYVTKKRG

Sequences:

>Translated_391_residues
MDLLKKFNPNLDKIEISLIRQFDQQVSSIPDVIKLTLGEPDFYTPEHVKQAGIVAIENNQSHYTGMAGLLELRQAASEFM
NKKYGLSYAAEDEILVTVGVTEAISSVLLSILVAGDEVLIPAPAYPGYEPLITLAGGSLVEIDTRANDFVLTPEMLEQAI
VEREGKVKAVILNYPANPTGVTYNRGQIKALAEVLKKHEVFVIADEVYSELNYTDQPHVSIAEYAPEQTIVLNGLSKSHA
MTGWRIGLIFAARELVAQIIKTHQYLVTSASTQSQFAAIEALKNGAYDALPMKKEYLKRRDYIIEKMSDLGFKIIEPDGA
FYIFAKIPADLEQDSFKFAVDFAKENAVAIIPGIAFGQYGEGFVRLSYAASMDMIEQAMARLTDYVTKKRG
>Mature_391_residues
MDLLKKFNPNLDKIEISLIRQFDQQVSSIPDVIKLTLGEPDFYTPEHVKQAGIVAIENNQSHYTGMAGLLELRQAASEFM
NKKYGLSYAAEDEILVTVGVTEAISSVLLSILVAGDEVLIPAPAYPGYEPLITLAGGSLVEIDTRANDFVLTPEMLEQAI
VEREGKVKAVILNYPANPTGVTYNRGQIKALAEVLKKHEVFVIADEVYSELNYTDQPHVSIAEYAPEQTIVLNGLSKSHA
MTGWRIGLIFAARELVAQIIKTHQYLVTSASTQSQFAAIEALKNGAYDALPMKKEYLKRRDYIIEKMSDLGFKIIEPDGA
FYIFAKIPADLEQDSFKFAVDFAKENAVAIIPGIAFGQYGEGFVRLSYAASMDMIEQAMARLTDYVTKKRG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=383, Percent_Identity=29.7650130548303, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI56713256, Length=382, Percent_Identity=29.3193717277487, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI95147551, Length=342, Percent_Identity=26.9005847953216, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI169881279, Length=342, Percent_Identity=26.9005847953216, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI169881281, Length=232, Percent_Identity=26.7241379310345, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI187936925, Length=369, Percent_Identity=25.7452574525745, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI14211921, Length=369, Percent_Identity=25.7452574525745, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI4507369, Length=389, Percent_Identity=23.1362467866324, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI149944424, Length=372, Percent_Identity=22.5806451612903, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786816, Length=354, Percent_Identity=28.5310734463277, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI1788722, Length=354, Percent_Identity=29.9435028248588, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1788627, Length=374, Percent_Identity=27.0053475935829, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1787909, Length=382, Percent_Identity=25.6544502617801, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787710, Length=336, Percent_Identity=25.8928571428571, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=396, Percent_Identity=28.5353535353535, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71994476, Length=396, Percent_Identity=28.5353535353535, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17567369, Length=381, Percent_Identity=27.2965879265092, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=22.9946524064171, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71981209, Length=367, Percent_Identity=22.8882833787466, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=361, Percent_Identity=28.808864265928, Blast_Score=133, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6320317, Length=375, Percent_Identity=23.2, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323118, Length=347, Percent_Identity=25.3602305475504, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=28.2776349614396, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=28.2776349614396, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=28.2776349614396, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=28.2776349614396, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI18859735, Length=392, Percent_Identity=21.9387755102041, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI45551451, Length=369, Percent_Identity=24.6612466124661, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641770, Length=369, Percent_Identity=24.6612466124661, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641760, Length=369, Percent_Identity=24.6612466124661, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641768, Length=369, Percent_Identity=24.6612466124661, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641766, Length=369, Percent_Identity=24.6612466124661, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24641764, Length=369, Percent_Identity=24.6612466124661, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 43261; Mature: 43261

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLKKFNPNLDKIEISLIRQFDQQVSSIPDVIKLTLGEPDFYTPEHVKQAGIVAIENNQ
CCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCEEEEECCC
SHYTGMAGLLELRQAASEFMNKKYGLSYAAEDEILVTVGVTEAISSVLLSILVAGDEVLI
CHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECHHHHHHHHHHHHHHCCCCEEE
PAPAYPGYEPLITLAGGSLVEIDTRANDFVLTPEMLEQAIVEREGKVKAVILNYPANPTG
ECCCCCCCCCEEEECCCCEEEEECCCCCEEECHHHHHHHHHHCCCCEEEEEEECCCCCCC
VTYNRGQIKALAEVLKKHEVFVIADEVYSELNYTDQPHVSIAEYAPEQTIVLNGLSKSHA
EEECCCHHHHHHHHHHHCCEEEEEHHHHHHCCCCCCCCEEHHHHCCCCEEEEECCCCCCC
MTGWRIGLIFAARELVAQIIKTHQYLVTSASTQSQFAAIEALKNGAYDALPMKKEYLKRR
CCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHH
DYIIEKMSDLGFKIIEPDGAFYIFAKIPADLEQDSFKFAVDFAKENAVAIIPGIAFGQYG
HHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCC
EGFVRLSYAASMDMIEQAMARLTDYVTKKRG
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLLKKFNPNLDKIEISLIRQFDQQVSSIPDVIKLTLGEPDFYTPEHVKQAGIVAIENNQ
CCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCEEEEECCC
SHYTGMAGLLELRQAASEFMNKKYGLSYAAEDEILVTVGVTEAISSVLLSILVAGDEVLI
CHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECHHHHHHHHHHHHHHCCCCEEE
PAPAYPGYEPLITLAGGSLVEIDTRANDFVLTPEMLEQAIVEREGKVKAVILNYPANPTG
ECCCCCCCCCEEEECCCCEEEEECCCCCEEECHHHHHHHHHHCCCCEEEEEEECCCCCCC
VTYNRGQIKALAEVLKKHEVFVIADEVYSELNYTDQPHVSIAEYAPEQTIVLNGLSKSHA
EEECCCHHHHHHHHHHHCCEEEEEHHHHHHCCCCCCCCEEHHHHCCCCEEEEECCCCCCC
MTGWRIGLIFAARELVAQIIKTHQYLVTSASTQSQFAAIEALKNGAYDALPMKKEYLKRR
CCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHH
DYIIEKMSDLGFKIIEPDGAFYIFAKIPADLEQDSFKFAVDFAKENAVAIIPGIAFGQYG
HHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCC
EGFVRLSYAASMDMIEQAMARLTDYVTKKRG
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2104615 [H]