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The map label for this gene is ycgM [C]

Identifier: 15669852

GI number: 15669852

Start: 1638656

End: 1639369

Strand: Direct

Name: ycgM [C]

Synonym: MJ1656

Alternate gene names: 15669852

Gene position: 1638656-1639369 (Clockwise)

Preceding gene: 15669851

Following gene: 15669853

Centisome position: 98.42

GC content: 31.37

Gene sequence:

>714_bases
ATGATTATTTCATTTGAGAAATTAGGAGAAAAATATAAAATAATTGATTTAAATTTAAATTCAATAAAGCAAAAGATTGG
TGATAGCTTGAATATAAAAGAGATTAAGCCAACAAAAATCATCTGTGTAGGTTTAAACTACATAGACCACGCAAAAGAGC
TTAATATGGAAATTCCAGAGTATCCAATAATATTCTTAAAGCCAACTTCAGCAATTATCTATAACGAAGATTACATAATA
AGACCAAGAATATCTAAGAGAGTTGATTATGAGGTTGAATTAGCCATAGTTATTGGAAAAAAATGCAAAAATATCAAAAA
AGATGAGGCAAATGACTATATAATGGGATATACAATTTTAAATGATGTAACAGCGAGAGATTTACAGCAGAAGGATGGAC
AATGGACAAGAGCTAAATCATTTGATACATTCTGCCCAATAGGACCGAGAATAGTTAAAGACATAGACCCAATGAACTTA
AATATTGAGTGTAGGGTTAATGGAGAAATAAAGCAGAAATCAAACACAAAAAATATGATTTTCGATGTTTATGAATTGGT
TGAGTTTGTCGCTTCAATAATGACACTCTATCCTGGAGATATCATTTCCACTGGTACTCCTCCAGGTGTTGGAGAGTTAA
AGGCTGGAGATGTTGTGGAGTGTGAGATTGAAGGTATTGGGATTTTAAGAAACTATGTTAAAGATGAAGAATAG

Upstream 100 bases:

>100_bases
TTATTTAAGAGATTGTTTTATAATTTTAGAGGACTATGTTGATGATTATTTAGATGAGGGTGATGAATTCAGTAGGGGAG
TTTTAGATGCATTTAGGGAG

Downstream 100 bases:

>100_bases
GTATTAAATTCTATTTGTTTATTAATTTACTTTAAAACAATTTTATGGTGATTTAATTGTTCTCTATCTCACATCCCGGA
GACTTTGAATCTTTAAAAAT

Product: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase HpcE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MIISFEKLGEKYKIIDLNLNSIKQKIGDSLNIKEIKPTKIICVGLNYIDHAKELNMEIPEYPIIFLKPTSAIIYNEDYII
RPRISKRVDYEVELAIVIGKKCKNIKKDEANDYIMGYTILNDVTARDLQQKDGQWTRAKSFDTFCPIGPRIVKDIDPMNL
NIECRVNGEIKQKSNTKNMIFDVYELVEFVASIMTLYPGDIISTGTPPGVGELKAGDVVECEIEGIGILRNYVKDEE

Sequences:

>Translated_237_residues
MIISFEKLGEKYKIIDLNLNSIKQKIGDSLNIKEIKPTKIICVGLNYIDHAKELNMEIPEYPIIFLKPTSAIIYNEDYII
RPRISKRVDYEVELAIVIGKKCKNIKKDEANDYIMGYTILNDVTARDLQQKDGQWTRAKSFDTFCPIGPRIVKDIDPMNL
NIECRVNGEIKQKSNTKNMIFDVYELVEFVASIMTLYPGDIISTGTPPGVGELKAGDVVECEIEGIGILRNYVKDEE
>Mature_237_residues
MIISFEKLGEKYKIIDLNLNSIKQKIGDSLNIKEIKPTKIICVGLNYIDHAKELNMEIPEYPIIFLKPTSAIIYNEDYII
RPRISKRVDYEVELAIVIGKKCKNIKKDEANDYIMGYTILNDVTARDLQQKDGQWTRAKSFDTFCPIGPRIVKDIDPMNL
NIECRVNGEIKQKSNTKNMIFDVYELVEFVASIMTLYPGDIISTGTPPGVGELKAGDVVECEIEGIGILRNYVKDEE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family

Homologues:

Organism=Homo sapiens, GI40786394, Length=209, Percent_Identity=51.1961722488038, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI156231349, Length=210, Percent_Identity=50.4761904761905, Blast_Score=212, Evalue=2e-55,
Organism=Homo sapiens, GI66348062, Length=193, Percent_Identity=39.8963730569948, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI215422413, Length=193, Percent_Identity=39.8963730569948, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI13654274, Length=193, Percent_Identity=39.8963730569948, Blast_Score=159, Evalue=3e-39,
Organism=Escherichia coli, GI1787428, Length=195, Percent_Identity=36.4102564102564, Blast_Score=141, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17557057, Length=189, Percent_Identity=43.9153439153439, Blast_Score=156, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6324161, Length=228, Percent_Identity=36.8421052631579, Blast_Score=138, Evalue=7e-34,
Organism=Drosophila melanogaster, GI28572127, Length=209, Percent_Identity=43.5406698564593, Blast_Score=170, Evalue=7e-43,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=39.7058823529412, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24663695, Length=208, Percent_Identity=38.9423076923077, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1656_METJA (Q59050)

Other databases:

- EMBL:   L77117
- PIR:   F64506
- RefSeq:   NP_248666.1
- ProteinModelPortal:   Q59050
- SMR:   Q59050
- GeneID:   1452565
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1656
- NMPDR:   fig|243232.1.peg.1703
- TIGR:   MJ1656
- HOGENOM:   HBG729228
- OMA:   EDYIIRP
- ProtClustDB:   CLSK2750022
- BioCyc:   MJAN243232:MJ_1656-MONOMER
- InterPro:   IPR002529
- InterPro:   IPR011234
- Gene3D:   G3DSA:3.90.850.10

Pfam domain/function: PF01557 FAA_hydrolase; SSF56529 Fumarylacetoacetase_C-rel

EC number: NA

Molecular weight: Translated: 26986; Mature: 26986

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISFEKLGEKYKIIDLNLNSIKQKIGDSLNIKEIKPTKIICVGLNYIDHAKELNMEIPE
CEEEHHHHCCEEEEEEECHHHHHHHHCCCCCEEEECCCEEEEEECCHHHHHHHCCCCCCC
YPIIFLKPTSAIIYNEDYIIRPRISKRVDYEVELAIVIGKKCKNIKKDEANDYIMGYTIL
CCEEEECCCCEEEECCCEEECCCCCCCCCEEEEEEEEECCHHCCCCCCCCCCEEEEEEEH
NDVTARDLQQKDGQWTRAKSFDTFCPIGPRIVKDIDPMNLNIECRVNGEIKQKSNTKNMI
HHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHCCCCCCEEEEEEECCCEECCCCCCHHH
FDVYELVEFVASIMTLYPGDIISTGTPPGVGELKAGDVVECEIEGIGILRNYVKDEE
HHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCC
>Mature Secondary Structure
MIISFEKLGEKYKIIDLNLNSIKQKIGDSLNIKEIKPTKIICVGLNYIDHAKELNMEIPE
CEEEHHHHCCEEEEEEECHHHHHHHHCCCCCEEEECCCEEEEEECCHHHHHHHCCCCCCC
YPIIFLKPTSAIIYNEDYIIRPRISKRVDYEVELAIVIGKKCKNIKKDEANDYIMGYTIL
CCEEEECCCCEEEECCCEEECCCCCCCCCEEEEEEEEECCHHCCCCCCCCCCEEEEEEEH
NDVTARDLQQKDGQWTRAKSFDTFCPIGPRIVKDIDPMNLNIECRVNGEIKQKSNTKNMI
HHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHCCCCCCEEEEEEECCCEECCCCCCHHH
FDVYELVEFVASIMTLYPGDIISTGTPPGVGELKAGDVVECEIEGIGILRNYVKDEE
HHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087