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The map label for this gene is pfkC

Identifier: 15669800

GI number: 15669800

Start: 1577299

End: 1578687

Strand: Reverse

Name: pfkC

Synonym: MJ1604

Alternate gene names: 15669800

Gene position: 1578687-1577299 (Counterclockwise)

Preceding gene: 15669801

Following gene: 15669795

Centisome position: 94.82

GC content: 30.45

Gene sequence:

>1389_bases
ATGTGTGATATTATGGAAATAAAAAAATTTATTGAGACAATAAAAGGAACTAAGCTTTTCACAGCATATAATACAAATGT
AGATGCAATAAAATATTTAAAAGACGAAGATGTACAAAAATTGGTAGATGAATTTAACCATAAAGATATAATAGAAAGAA
TGGAAGAATATCCAAGAATTATTGAAGAACCGTTAGATTTCGTTGCAAGGTTAGTTCATAGTATAAAGACGGGAAAACCG
GCAGAGGTTCCAATAAAGGATGATAAAAAGTTACATGAGTGGTTTGATAGAATTAAATATGATGAGGAAAGAATGGGAGG
ACAGGCAGGGATTGTTTCTAATTTAATGGCTACCCTGCAGATAGATAAAATAATTGTTTATACTCCATTTTTATCAAAAA
AACAGGCAGAGATGTTTGTTGATTATGATAATTTGCTTTATCCATTAGTTGAAAATGGAAATCTTGTATTAAAAAAAGTT
AGAGAGGCATATAGAGATGACCCAATAAAGATAAACAGGATATTCGAATTCAAAAAAGGGTTAAAGTTTAAGTTAAATGG
AGAGGAAATAACTGCTAAGCAATCTACAAGATTTATTGTTGCCTCAAGACCTGAAGCTTTGAGGATTGAGATAAAAGATG
ATGTTAGGAAATTTCTGCCGAAGATTGGAGAGGCTGTGGATTGTGCATTTTTATCTGGTTATCAGGCAATTAAAGAGGAA
TATAGAGATGGGAAAACAGCAAAATATTACTTTGAGAGGGCTGAAGAGGATATAAAATTATTAAAAAAGAATAAAAACAT
CAAAACCCACTTGGAATTTGCCTCCATATCAAATATAGAGATTAGAAAGATGGTTGTTGATTATATTTTAAGTAACGTGG
AAAGCGTAGGAATGGATGAAACAGAGATAGCTAATGTTTTGCATATCTTGGGCTATGATGAGTTAAGCAATAATATTTTA
AAAGACAGTTTTATTGAGGATGTGATTGAAGGGGCTAAGATATTACTGGATAAATTTAAAAACTTGGAGGTTGTTCAAGT
TCATACAATATATTATATTTTGTTTGTTTGTAGGGCTGATAATCCACTATCTAAAGAAGAACTTGAAGAATGTTTAGAAT
TCTCTACTATCTTGGCATCAACAAAGGCAAAACTTGGAAATATAAGGGCAATAGATGATTTACATGAAGGTTTAAAAATC
CCTCACAATAAATATGGGGATTTATTAAAGGAGATTGCTGAGAAATTTAACGATAATAATTATAAAATAGCTTTATCTCC
ATCAAGATATGTTGAAAAACCAAAATCTACAGTAGGTTTAGGAGATACAATATCAAGTGGGGCGTTTGTTTATTATGTAT
CTCTATTAAATAAAAAAAGAATGAGCTAA

Upstream 100 bases:

>100_bases
AATCAACCAGCAGTTGAAGAGGAGAAAAAAATTTGCTGGAGATTGATTAAACAATAAATAATATTTCTAATTCTTTTTCT
TTATTAGTAGATATCTTAAA

Downstream 100 bases:

>100_bases
AAACTAATTTTTTATTTTTTAAGTGTTTTTACTCCTTTTTTAGTTCCAACTAAAACCTTATCTACCTTTGTAAAGATACC
ATTTTCAACTACTCCAGGAA

Product: ADP-specific phosphofructokinase

Products: NA

Alternate protein names: ADP-GK; ADP-GK/PFK; ADP-Pfk; ADP-dependent glucokinase; ADP-dependent phosphofructokinase

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MCDIMEIKKFIETIKGTKLFTAYNTNVDAIKYLKDEDVQKLVDEFNHKDIIERMEEYPRIIEEPLDFVARLVHSIKTGKP
AEVPIKDDKKLHEWFDRIKYDEERMGGQAGIVSNLMATLQIDKIIVYTPFLSKKQAEMFVDYDNLLYPLVENGNLVLKKV
REAYRDDPIKINRIFEFKKGLKFKLNGEEITAKQSTRFIVASRPEALRIEIKDDVRKFLPKIGEAVDCAFLSGYQAIKEE
YRDGKTAKYYFERAEEDIKLLKKNKNIKTHLEFASISNIEIRKMVVDYILSNVESVGMDETEIANVLHILGYDELSNNIL
KDSFIEDVIEGAKILLDKFKNLEVVQVHTIYYILFVCRADNPLSKEELEECLEFSTILASTKAKLGNIRAIDDLHEGLKI
PHNKYGDLLKEIAEKFNDNNYKIALSPSRYVEKPKSTVGLGDTISSGAFVYYVSLLNKKRMS

Sequences:

>Translated_462_residues
MCDIMEIKKFIETIKGTKLFTAYNTNVDAIKYLKDEDVQKLVDEFNHKDIIERMEEYPRIIEEPLDFVARLVHSIKTGKP
AEVPIKDDKKLHEWFDRIKYDEERMGGQAGIVSNLMATLQIDKIIVYTPFLSKKQAEMFVDYDNLLYPLVENGNLVLKKV
REAYRDDPIKINRIFEFKKGLKFKLNGEEITAKQSTRFIVASRPEALRIEIKDDVRKFLPKIGEAVDCAFLSGYQAIKEE
YRDGKTAKYYFERAEEDIKLLKKNKNIKTHLEFASISNIEIRKMVVDYILSNVESVGMDETEIANVLHILGYDELSNNIL
KDSFIEDVIEGAKILLDKFKNLEVVQVHTIYYILFVCRADNPLSKEELEECLEFSTILASTKAKLGNIRAIDDLHEGLKI
PHNKYGDLLKEIAEKFNDNNYKIALSPSRYVEKPKSTVGLGDTISSGAFVYYVSLLNKKRMS
>Mature_462_residues
MCDIMEIKKFIETIKGTKLFTAYNTNVDAIKYLKDEDVQKLVDEFNHKDIIERMEEYPRIIEEPLDFVARLVHSIKTGKP
AEVPIKDDKKLHEWFDRIKYDEERMGGQAGIVSNLMATLQIDKIIVYTPFLSKKQAEMFVDYDNLLYPLVENGNLVLKKV
REAYRDDPIKINRIFEFKKGLKFKLNGEEITAKQSTRFIVASRPEALRIEIKDDVRKFLPKIGEAVDCAFLSGYQAIKEE
YRDGKTAKYYFERAEEDIKLLKKNKNIKTHLEFASISNIEIRKMVVDYILSNVESVGMDETEIANVLHILGYDELSNNIL
KDSFIEDVIEGAKILLDKFKNLEVVQVHTIYYILFVCRADNPLSKEELEECLEFSTILASTKAKLGNIRAIDDLHEGLKI
PHNKYGDLLKEIAEKFNDNNYKIALSPSRYVEKPKSTVGLGDTISSGAFVYYVSLLNKKRMS

Specific function: Catalyzes the phosphorylation of fructose 6-phosphate and D-glucose to fructose 1,6-bisphosphate and D-glucose 6- phosphate, respectively, using ADP as the phosphate donor

COG id: COG4809

COG function: function code G; Archaeal ADP-dependent phosphofructokinase/glucokinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ADPK (ADP-dependent kinase) domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): K6PF_METJA (Q58999)

Other databases:

- EMBL:   L77117
- PIR:   C64500
- RefSeq:   NP_248614.1
- ProteinModelPortal:   Q58999
- SMR:   Q58999
- GeneID:   1452513
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1604
- NMPDR:   fig|243232.1.peg.1651
- TIGR:   MJ1604
- HOGENOM:   HBG645711
- OMA:   KKQAEMF
- ProtClustDB:   PRK03979
- BioCyc:   MJAN243232:MJ_1604-MONOMER
- BRENDA:   2.7.1.146
- BRENDA:   2.7.1.147
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00561
- InterPro:   IPR007666
- InterPro:   IPR015990
- InterPro:   IPR011790
- PANTHER:   PTHR21208
- PIRSF:   PIRSF015883
- TIGRFAMs:   TIGR02045

Pfam domain/function: PF04587 ADP_PFK_GK

EC number: =2.7.1.146; =2.7.1.147

Molecular weight: Translated: 53362; Mature: 53362

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS51255 ADPK

Important sites: ACT_SITE 442-442

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDIMEIKKFIETIKGTKLFTAYNTNVDAIKYLKDEDVQKLVDEFNHKDIIERMEEYPRI
CCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IEEPLDFVARLVHSIKTGKPAEVPIKDDKKLHEWFDRIKYDEERMGGQAGIVSNLMATLQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHH
IDKIIVYTPFLSKKQAEMFVDYDNLLYPLVENGNLVLKKVREAYRDDPIKINRIFEFKKG
HCEEEEECCCCCCCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEHHHHHHHCC
LKFKLNGEEITAKQSTRFIVASRPEALRIEIKDDVRKFLPKIGEAVDCAFLSGYQAIKEE
CEEEECCCEEECCCCCEEEEECCCCEEEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
YRDGKTAKYYFERAEEDIKLLKKNKNIKTHLEFASISNIEIRKMVVDYILSNVESVGMDE
HCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCH
TEIANVLHILGYDELSNNILKDSFIEDVIEGAKILLDKFKNLEVVQVHTIYYILFVCRAD
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCC
NPLSKEELEECLEFSTILASTKAKLGNIRAIDDLHEGLKIPHNKYGDLLKEIAEKFNDNN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
YKIALSPSRYVEKPKSTVGLGDTISSGAFVYYVSLLNKKRMS
EEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MCDIMEIKKFIETIKGTKLFTAYNTNVDAIKYLKDEDVQKLVDEFNHKDIIERMEEYPRI
CCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IEEPLDFVARLVHSIKTGKPAEVPIKDDKKLHEWFDRIKYDEERMGGQAGIVSNLMATLQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHH
IDKIIVYTPFLSKKQAEMFVDYDNLLYPLVENGNLVLKKVREAYRDDPIKINRIFEFKKG
HCEEEEECCCCCCCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEHHHHHHHCC
LKFKLNGEEITAKQSTRFIVASRPEALRIEIKDDVRKFLPKIGEAVDCAFLSGYQAIKEE
CEEEECCCEEECCCCCEEEEECCCCEEEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
YRDGKTAKYYFERAEEDIKLLKKNKNIKTHLEFASISNIEIRKMVVDYILSNVESVGMDE
HCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCH
TEIANVLHILGYDELSNNILKDSFIEDVIEGAKILLDKFKNLEVVQVHTIYYILFVCRAD
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCC
NPLSKEELEECLEFSTILASTKAKLGNIRAIDDLHEGLKIPHNKYGDLLKEIAEKFNDNN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
YKIALSPSRYVEKPKSTVGLGDTISSGAFVYYVSLLNKKRMS
EEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 11717273