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The map label for this gene is trxB [C]

Identifier: 15669731

GI number: 15669731

Start: 1513796

End: 1514701

Strand: Reverse

Name: trxB [C]

Synonym: MJ1536

Alternate gene names: 15669731

Gene position: 1514701-1513796 (Counterclockwise)

Preceding gene: 15669732

Following gene: 15669728

Centisome position: 90.97

GC content: 32.45

Gene sequence:

>906_bases
ATGATTCACGACACAATAATTATTGGTGCTGGACCTGGAGGATTAACAGCTGGCATATATGCAATGAGGGGAAAGTTAAA
TGCTCTATGTATAGAAAAAGAAAATGCTGGAGGTAGGATAGCTGAAGCTGGTATTGTAGAAAACTACCCTGGATTTGAAG
AGATTAGAGGATATGAATTAGCTGAAAAATTTAAGAATCATGCTGAAAAGTTTAAATTACCTATAATCTACGATGAAGTC
ATTAAAATAGAAACTAAAGAGAGACCATTTAAAGTTATAACAAAAAATTCTGAGTATTTAACTAAAACTATAGTTATAGC
AACTGGGACAAAACCTAAAAAATTAGGTTTAAACGAAGATAAATTTATCGGAAGAGGAATTAGTTACTGTACAATGTGTG
ATGCCTTCTTCTATTTGAATAAAGAGGTTATAGTGATTGGGAGGGATACACCAGCAATCATGAGTGCTATAAATTTAAAA
GACATTGCTAAAAAAGTTATTGTAATTACTGATAAGTCAGAGTTAAAGGCTGCTGAGTCAATAATGTTAGATAAGCTTAA
AGAAGCCAACAATGTTGAAATAATATACAATGCCAAACCATTGGAAATTGTTGGAGAAGAAAGAGCTGAAGGAGTTAAAA
TATCAGTTAATGGAAAGGAAGAGATAATAAAAGCAGATGGGATATTTATAAGCTTGGGACATGTTCCAAACACTGAATTT
TTAAAGGATAGTGGTATAGAGTTAGATAAAAAGGGATTTATCAAAACAGATGAAAACTGTAGAACAAATATAGATGGAAT
TTATGCTGTAGGGGATGTTAGGGGAGGGGTTATGCAAGTAGCTAAAGCTGTAGGAGATGGGTGTGTGGCTATGGCAAATA
TTATTAAATACTTGCAAAAATTATAA

Upstream 100 bases:

>100_bases
CTTTTATTCCTAAATTCTCCGATATGTTGCAACAAAAATTGCGAAGAGTGTTTAGAAATCTTTATAAATAAAATTAAAAT
ATTAAAAATGGGGTGAAAAA

Downstream 100 bases:

>100_bases
AAATTAAAATATTTTTAGAAGAATTACTAAATTATTTTAAATTATTTTGTGTTAATGGGATGTCATAAACGATATTTCCC
ATTTTAAAATCTAATCTTAG

Product: thioredoxin reductase TrxB

Products: NA

Alternate protein names: TRXR

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MIHDTIIIGAGPGGLTAGIYAMRGKLNALCIEKENAGGRIAEAGIVENYPGFEEIRGYELAEKFKNHAEKFKLPIIYDEV
IKIETKERPFKVITKNSEYLTKTIVIATGTKPKKLGLNEDKFIGRGISYCTMCDAFFYLNKEVIVIGRDTPAIMSAINLK
DIAKKVIVITDKSELKAAESIMLDKLKEANNVEIIYNAKPLEIVGEERAEGVKISVNGKEEIIKADGIFISLGHVPNTEF
LKDSGIELDKKGFIKTDENCRTNIDGIYAVGDVRGGVMQVAKAVGDGCVAMANIIKYLQKL

Sequences:

>Translated_301_residues
MIHDTIIIGAGPGGLTAGIYAMRGKLNALCIEKENAGGRIAEAGIVENYPGFEEIRGYELAEKFKNHAEKFKLPIIYDEV
IKIETKERPFKVITKNSEYLTKTIVIATGTKPKKLGLNEDKFIGRGISYCTMCDAFFYLNKEVIVIGRDTPAIMSAINLK
DIAKKVIVITDKSELKAAESIMLDKLKEANNVEIIYNAKPLEIVGEERAEGVKISVNGKEEIIKADGIFISLGHVPNTEF
LKDSGIELDKKGFIKTDENCRTNIDGIYAVGDVRGGVMQVAKAVGDGCVAMANIIKYLQKL
>Mature_301_residues
MIHDTIIIGAGPGGLTAGIYAMRGKLNALCIEKENAGGRIAEAGIVENYPGFEEIRGYELAEKFKNHAEKFKLPIIYDEV
IKIETKERPFKVITKNSEYLTKTIVIATGTKPKKLGLNEDKFIGRGISYCTMCDAFFYLNKEVIVIGRDTPAIMSAINLK
DIAKKVIVITDKSELKAAESIMLDKLKEANNVEIIYNAKPLEIVGEERAEGVKISVNGKEEIIKADGIFISLGHVPNTEF
LKDSGIELDKKGFIKTDENCRTNIDGIYAVGDVRGGVMQVAKAVGDGCVAMANIIKYLQKL

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=34.0836012861736, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI87081763, Length=306, Percent_Identity=30.0653594771242, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786307, Length=90, Percent_Identity=35.5555555555556, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=31.25, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6321898, Length=318, Percent_Identity=30.5031446540881, Blast_Score=139, Evalue=7e-34,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRXB_METJA (Q58931)

Other databases:

- EMBL:   L77117
- PIR:   G64491
- RefSeq:   NP_248544.1
- ProteinModelPortal:   Q58931
- SMR:   Q58931
- GeneID:   1452444
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1536
- NMPDR:   fig|243232.1.peg.1581
- TIGR:   MJ1536
- HOGENOM:   HBG669726
- OMA:   FDEVKTV
- ProtClustDB:   CLSK876613
- BioCyc:   MJAN243232:MJ_1536-MONOMER
- BRENDA:   1.8.1.9
- GO:   GO:0005737
- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982
- PRINTS:   PR00368
- PRINTS:   PR00469
- TIGRFAMs:   TIGR01292

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.8.1.9

Molecular weight: Translated: 33035; Mature: 33035

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHDTIIIGAGPGGLTAGIYAMRGKLNALCIEKENAGGRIAEAGIVENYPGFEEIRGYEL
CCEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCCHHHHCCHHH
AEKFKNHAEKFKLPIIYDEVIKIETKERPFKVITKNSEYLTKTIVIATGTKPKKLGLNED
HHHHHHHHHHCCCCEEEECEEEEECCCCCEEEEECCCCEEEEEEEEEECCCCCCCCCCCC
KFIGRGISYCTMCDAFFYLNKEVIVIGRDTPAIMSAINLKDIAKKVIVITDKSELKAAES
HHHCCCCHHHHHHHHHHEECCEEEEEECCCHHHHHHCCHHHHCCEEEEEECCHHHHHHHH
IMLDKLKEANNVEIIYNAKPLEIVGEERAEGVKISVNGKEEIIKADGIFISLGHVPNTEF
HHHHHHHCCCCEEEEECCCCCEEECCCCCCCEEEEECCHHHEEEECCEEEEECCCCCCHH
LKDSGIELDKKGFIKTDENCRTNIDGIYAVGDVRGGVMQVAKAVGDGCVAMANIIKYLQK
HHCCCCEECCCCCEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHC
L
C
>Mature Secondary Structure
MIHDTIIIGAGPGGLTAGIYAMRGKLNALCIEKENAGGRIAEAGIVENYPGFEEIRGYEL
CCEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCCHHHHCCHHH
AEKFKNHAEKFKLPIIYDEVIKIETKERPFKVITKNSEYLTKTIVIATGTKPKKLGLNED
HHHHHHHHHHCCCCEEEECEEEEECCCCCEEEEECCCCEEEEEEEEEECCCCCCCCCCCC
KFIGRGISYCTMCDAFFYLNKEVIVIGRDTPAIMSAINLKDIAKKVIVITDKSELKAAES
HHHCCCCHHHHHHHHHHEECCEEEEEECCCHHHHHHCCHHHHCCEEEEEECCHHHHHHHH
IMLDKLKEANNVEIIYNAKPLEIVGEERAEGVKISVNGKEEIIKADGIFISLGHVPNTEF
HHHHHHHCCCCEEEEECCCCCEEECCCCCCCEEEEECCHHHEEEECCEEEEECCCCCCHH
LKDSGIELDKKGFIKTDENCRTNIDGIYAVGDVRGGVMQVAKAVGDGCVAMANIIKYLQK
HHCCCCEECCCCCEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087