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The map label for this gene is ade

Identifier: 15669650

GI number: 15669650

Start: 1428276

End: 1429946

Strand: Direct

Name: ade

Synonym: MJ1459

Alternate gene names: 15669650

Gene position: 1428276-1429946 (Clockwise)

Preceding gene: 15669649

Following gene: 15669655

Centisome position: 85.78

GC content: 30.22

Gene sequence:

>1671_bases
ATGATTGTCTTCAAAAATACAAAGATTATTGATGTATATACTGGAGAGGTTGTTAAAGGAAATGTTGCAGTTGAGAGGGA
TAAAATATCCTTTGTGGATTTAAATGATGAAATTGATAAGATAATTGAAAAAATAAAGGAGGATGTTAAAGTTATTGACT
TAAAAGGAAAATATTTATCTCCAACATTTATAGATGGGCATATACATATAGAATCTTCCCATCTCATCCCATCAGAGTTT
GAGAAATTTGTATTAAAAAGCGGAGTTAGCAAAGTAGTTATAGACCCGCATGAAATAGCAAATATTGCTGGAAAAGAAGG
AATTTTGTTTATGTTGAATGATGCCAAAATTTTAGATGTCTATGTTATGCTTCCTTCCTGTGTTCCAGCTACAAACTTAG
AAACAAGTGGAGCTGAGATTACAGCAGAGAATATTGAAGAACTCATTCTTTTAGATAATGTCTTAGGTTTAGGAGAGGTT
ATGAACTATCCTGCAGTAATAAATGAAGATGAAGAGATGTTAAAAAAGATAGAAGTAGCTAAAAAATACAATAAATTGAT
AGATGGGCATTGTCCAAAATTAAAAGGTTGGGAGTTAAACAAATATATATCTCATGGAATAATGAGCGACCATGAGAGTG
TTGATGAAGATGAGGCATTAGAAAAGCTTAGATTGGGATTAAAATTAATGATTAGAGAAGGAACAGCATCAAAAAACATC
TATTTGCTTAATATATGCAAAAAGATAAAAGATTTTAGGAATATAATGTTGGTTAGTGATGACGTCTGTATTAAAGATTT
AGACGGCTACATGTTAAATATTTTAAGAAAAGCCACAAACTATGTTTCTCCAATTGAAGCTATTCAAATGGTTACAATAA
ATCCAGCAAATTATTTTGGGTTTGATGTAGGAATTAAAGCTGGAAATGAGGCAAGTTTTGTAATCTTTGAAGATTTAGAC
AATTTTAAAGTTTATAACATTGTCATAAAAGGAAGATTCTTAGATGATGTTTTAAATGAACTAAATAAAAATAAAAAAAG
AAAAATTCCCGAAAAGCTCATGAATACTTTAAAATACCAATACAAAAACGAAGGTGATTTTTTAATTAAAGGGATTGATT
ATAAGGAGAGAGATGGATTTATTAGAGTAATAAAACCATTAAAAGATTCTCTAATAACTGAAGAGCTAATATTTAGCACT
GAAGAAATAAAAATATTACTGAATGAAAATGCTATAAATAAAATCTTCGTTATAGAGAGGCATAAAAATACTGGAAATAT
TGGAAAGGGTTTAATATACAACTTCTTGGAGGAGGGAGCTTTAGCCTCTTCCTATGCTCACGATTCTCATAATGTAATAG
CCATAGGAAATAATGAGAAAGATTTAGCCTTAGCTGTAAATAAATTAAAAGATATTGGTGGAGGATTTATAGCTGCTAAG
GATGGGGAAGTTGTTGAATATCTTCCTCTACCAGTTGGAGGGATAATGGGAGATGATGGAAAATACATAGCTGAGAAGAT
TAATGCTTTGTATAAAAAAATAGAAGGTTGGAGTTCTTTTGAGAACCCATTTTTAAGTATGAGCTTTTTCTCTCTCCCTG
TGATTCCTGAGCTAAAAATAACTGATAAAGGTTTGGTTAAAGATATGCAGTTGGTTGATTTATTTATTTAG

Upstream 100 bases:

>100_bases
GCTTTGGGTTATGAAACTCCATGATTTTCATTTAATTTTTTCCTATTAATTTTCTCCTAAAAAGTTTCTTTAACATAAAT
AAGGTTAAAGGGAGAGCTCT

Downstream 100 bases:

>100_bases
CTCATCAACTTCCTTAACTTCAAACACACATTTATCTTTTCCTTGAGAAACACATTCAACCTCATTAACAACAAATTTCT
TTTTAAATATCTCTTCTAAA

Product: adenine deaminase AdeC

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MIVFKNTKIIDVYTGEVVKGNVAVERDKISFVDLNDEIDKIIEKIKEDVKVIDLKGKYLSPTFIDGHIHIESSHLIPSEF
EKFVLKSGVSKVVIDPHEIANIAGKEGILFMLNDAKILDVYVMLPSCVPATNLETSGAEITAENIEELILLDNVLGLGEV
MNYPAVINEDEEMLKKIEVAKKYNKLIDGHCPKLKGWELNKYISHGIMSDHESVDEDEALEKLRLGLKLMIREGTASKNI
YLLNICKKIKDFRNIMLVSDDVCIKDLDGYMLNILRKATNYVSPIEAIQMVTINPANYFGFDVGIKAGNEASFVIFEDLD
NFKVYNIVIKGRFLDDVLNELNKNKKRKIPEKLMNTLKYQYKNEGDFLIKGIDYKERDGFIRVIKPLKDSLITEELIFST
EEIKILLNENAINKIFVIERHKNTGNIGKGLIYNFLEEGALASSYAHDSHNVIAIGNNEKDLALAVNKLKDIGGGFIAAK
DGEVVEYLPLPVGGIMGDDGKYIAEKINALYKKIEGWSSFENPFLSMSFFSLPVIPELKITDKGLVKDMQLVDLFI

Sequences:

>Translated_556_residues
MIVFKNTKIIDVYTGEVVKGNVAVERDKISFVDLNDEIDKIIEKIKEDVKVIDLKGKYLSPTFIDGHIHIESSHLIPSEF
EKFVLKSGVSKVVIDPHEIANIAGKEGILFMLNDAKILDVYVMLPSCVPATNLETSGAEITAENIEELILLDNVLGLGEV
MNYPAVINEDEEMLKKIEVAKKYNKLIDGHCPKLKGWELNKYISHGIMSDHESVDEDEALEKLRLGLKLMIREGTASKNI
YLLNICKKIKDFRNIMLVSDDVCIKDLDGYMLNILRKATNYVSPIEAIQMVTINPANYFGFDVGIKAGNEASFVIFEDLD
NFKVYNIVIKGRFLDDVLNELNKNKKRKIPEKLMNTLKYQYKNEGDFLIKGIDYKERDGFIRVIKPLKDSLITEELIFST
EEIKILLNENAINKIFVIERHKNTGNIGKGLIYNFLEEGALASSYAHDSHNVIAIGNNEKDLALAVNKLKDIGGGFIAAK
DGEVVEYLPLPVGGIMGDDGKYIAEKINALYKKIEGWSSFENPFLSMSFFSLPVIPELKITDKGLVKDMQLVDLFI
>Mature_556_residues
MIVFKNTKIIDVYTGEVVKGNVAVERDKISFVDLNDEIDKIIEKIKEDVKVIDLKGKYLSPTFIDGHIHIESSHLIPSEF
EKFVLKSGVSKVVIDPHEIANIAGKEGILFMLNDAKILDVYVMLPSCVPATNLETSGAEITAENIEELILLDNVLGLGEV
MNYPAVINEDEEMLKKIEVAKKYNKLIDGHCPKLKGWELNKYISHGIMSDHESVDEDEALEKLRLGLKLMIREGTASKNI
YLLNICKKIKDFRNIMLVSDDVCIKDLDGYMLNILRKATNYVSPIEAIQMVTINPANYFGFDVGIKAGNEASFVIFEDLD
NFKVYNIVIKGRFLDDVLNELNKNKKRKIPEKLMNTLKYQYKNEGDFLIKGIDYKERDGFIRVIKPLKDSLITEELIFST
EEIKILLNENAINKIFVIERHKNTGNIGKGLIYNFLEEGALASSYAHDSHNVIAIGNNEKDLALAVNKLKDIGGGFIAAK
DGEVVEYLPLPVGGIMGDDGKYIAEKINALYKKIEGWSSFENPFLSMSFFSLPVIPELKITDKGLVKDMQLVDLFI

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=558, Percent_Identity=32.4372759856631, Blast_Score=273, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_METJA (Q58854)

Other databases:

- EMBL:   L77117
- PIR:   B64482
- RefSeq:   NP_248463.1
- ProteinModelPortal:   Q58854
- GeneID:   1452363
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1459
- NMPDR:   fig|243232.1.peg.1500
- TIGR:   MJ1459
- HOGENOM:   HBG725357
- OMA:   GKIITEH
- ProtClustDB:   CLSK796877
- BioCyc:   MJAN243232:MJ_1459-MONOMER
- BRENDA:   3.5.4.2
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 62624; Mature: 62624

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFKNTKIIDVYTGEVVKGNVAVERDKISFVDLNDEIDKIIEKIKEDVKVIDLKGKYLS
CEEECCCEEEEEECCCEEECCEEEEECCEEEEECCHHHHHHHHHHHCCCEEEEECCCCCC
PTFIDGHIHIESSHLIPSEFEKFVLKSGVSKVVIDPHEIANIAGKEGILFMLNDAKILDV
CEEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEECHHHHHHCCCCCCEEEEECCCEEEEE
YVMLPSCVPATNLETSGAEITAENIEELILLDNVLGLGEVMNYPAVINEDEEMLKKIEVA
EEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHH
KKYNKLIDGHCPKLKGWELNKYISHGIMSDHESVDEDEALEKLRLGLKLMIREGTASKNI
HHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCE
YLLNICKKIKDFRNIMLVSDDVCIKDLDGYMLNILRKATNYVSPIEAIQMVTINPANYFG
EEHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCE
FDVGIKAGNEASFVIFEDLDNFKVYNIVIKGRFLDDVLNELNKNKKRKIPEKLMNTLKYQ
EEEEEECCCCEEEEEEECCCCEEEEEEEEECCHHHHHHHHHCCCHHHCCHHHHHHHHHHH
YKNEGDFLIKGIDYKERDGFIRVIKPLKDSLITEELIFSTEEIKILLNENAINKIFVIER
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEE
HKNTGNIGKGLIYNFLEEGALASSYAHDSHNVIAIGNNEKDLALAVNKLKDIGGGFIAAK
CCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEC
DGEVVEYLPLPVGGIMGDDGKYIAEKINALYKKIEGWSSFENPFLSMSFFSLPVIPELKI
CCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEHCCCCCCCCEEE
TDKGLVKDMQLVDLFI
CCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIVFKNTKIIDVYTGEVVKGNVAVERDKISFVDLNDEIDKIIEKIKEDVKVIDLKGKYLS
CEEECCCEEEEEECCCEEECCEEEEECCEEEEECCHHHHHHHHHHHCCCEEEEECCCCCC
PTFIDGHIHIESSHLIPSEFEKFVLKSGVSKVVIDPHEIANIAGKEGILFMLNDAKILDV
CEEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEECHHHHHHCCCCCCEEEEECCCEEEEE
YVMLPSCVPATNLETSGAEITAENIEELILLDNVLGLGEVMNYPAVINEDEEMLKKIEVA
EEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHH
KKYNKLIDGHCPKLKGWELNKYISHGIMSDHESVDEDEALEKLRLGLKLMIREGTASKNI
HHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCE
YLLNICKKIKDFRNIMLVSDDVCIKDLDGYMLNILRKATNYVSPIEAIQMVTINPANYFG
EEHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCE
FDVGIKAGNEASFVIFEDLDNFKVYNIVIKGRFLDDVLNELNKNKKRKIPEKLMNTLKYQ
EEEEEECCCCEEEEEEECCCCEEEEEEEEECCHHHHHHHHHCCCHHHCCHHHHHHHHHHH
YKNEGDFLIKGIDYKERDGFIRVIKPLKDSLITEELIFSTEEIKILLNENAINKIFVIER
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEE
HKNTGNIGKGLIYNFLEEGALASSYAHDSHNVIAIGNNEKDLALAVNKLKDIGGGFIAAK
CCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEC
DGEVVEYLPLPVGGIMGDDGKYIAEKINALYKKIEGWSSFENPFLSMSFFSLPVIPELKI
CCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEHCCCCCCCCEEE
TDKGLVKDMQLVDLFI
CCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087