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The map label for this gene is aroK

Identifier: 15669631

GI number: 15669631

Start: 1407283

End: 1408131

Strand: Direct

Name: aroK

Synonym: MJ1440

Alternate gene names: 15669631

Gene position: 1407283-1408131 (Clockwise)

Preceding gene: 15669630

Following gene: 15669632

Centisome position: 84.52

GC content: 30.62

Gene sequence:

>849_bases
ATGGAAGGAAAAGCCTATGCATTAGCATCTGGGACAATAATAAACGCTATAGCAACAGGTAAGGGTTCAGCTTTTGGATT
AGATTTAAAGGTTTATGCCAAAGTTAAACTTATAGATGATGGAAAAAACAAAATAGAGGGTAAAGTTTTAGATAATCCAA
ACATTAAGCCAAATTTAATAGTAAGATGTGTCAAAAATACTTTAGATTATTTTGGGCTGAATTACTCTGCCTATGTTGAA
ACAAAGACAGAAATTCCTATAAAATCTGGATTGAGTAGTAGTTCAGCCACTTCTAACGCAGTTGTTTTGGCAACATTTGA
TGCATTAGGGGAAAAAATAGATGATGAGCTAATATTAAATTTAGGGATAAAATCAAGTTTTGATGAAAAATTAACTGTTA
CTGGAGCTTATGATGATGCTACTGCATCATACTATGGGGGAATAACAATAACTGACAATATAGAAAGAAAAATTTTAAAA
AGAGATAAGATGAGAGATGATTTAAACGTCTTAATATTAATTCCAAATTTAGAAAAGAATGTTGATGTAAATAGAATGAA
GCTAATAAAGGATTATGTTGAAATTGCCTTTAATGAGGCTATAAATGGAAACTATTTCAAAGCTTTATTTTTAAATGGAA
TTCTTTATGCATCAGCTTTAAACTTTCCAACAAACATAGCAATAGACGCATTAGATGCTGGGGCAATAACAGCCGGTTTA
TCTGGAACAGGTCCAAGTTATATAGCCATGGTTGAAGATGAAAATGTTGAAAAGGTAAAAGAAAAATTAAATAGGTATGG
AAAGGTTATTTTAACTAAACCAAACAATGATGGAGCTTCTATTTACTAA

Upstream 100 bases:

>100_bases
TTATCATGAACCTTTAATAAAGGTTCATCAAAATGAGTGGGGCTTCACTTCGTTCAGCTCCACTTTATTTATAGCTACAA
AAGTAATGGAGTGATTTTTT

Downstream 100 bases:

>100_bases
TTTTAATTTTTTATTTTTTATGAAATTTATCATGATTTTTAATGACAAATTATAAATACTAAAATTGTAATAATGTAGTA
ATAAAATCTACAAAAAATTA

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MEGKAYALASGTIINAIATGKGSAFGLDLKVYAKVKLIDDGKNKIEGKVLDNPNIKPNLIVRCVKNTLDYFGLNYSAYVE
TKTEIPIKSGLSSSSATSNAVVLATFDALGEKIDDELILNLGIKSSFDEKLTVTGAYDDATASYYGGITITDNIERKILK
RDKMRDDLNVLILIPNLEKNVDVNRMKLIKDYVEIAFNEAINGNYFKALFLNGILYASALNFPTNIAIDALDAGAITAGL
SGTGPSYIAMVEDENVEKVKEKLNRYGKVILTKPNNDGASIY

Sequences:

>Translated_282_residues
MEGKAYALASGTIINAIATGKGSAFGLDLKVYAKVKLIDDGKNKIEGKVLDNPNIKPNLIVRCVKNTLDYFGLNYSAYVE
TKTEIPIKSGLSSSSATSNAVVLATFDALGEKIDDELILNLGIKSSFDEKLTVTGAYDDATASYYGGITITDNIERKILK
RDKMRDDLNVLILIPNLEKNVDVNRMKLIKDYVEIAFNEAINGNYFKALFLNGILYASALNFPTNIAIDALDAGAITAGL
SGTGPSYIAMVEDENVEKVKEKLNRYGKVILTKPNNDGASIY
>Mature_282_residues
MEGKAYALASGTIINAIATGKGSAFGLDLKVYAKVKLIDDGKNKIEGKVLDNPNIKPNLIVRCVKNTLDYFGLNYSAYVE
TKTEIPIKSGLSSSSATSNAVVLATFDALGEKIDDELILNLGIKSSFDEKLTVTGAYDDATASYYGGITITDNIERKILK
RDKMRDDLNVLILIPNLEKNVDVNRMKLIKDYVEIAFNEAINGNYFKALFLNGILYASALNFPTNIAIDALDAGAITAGL
SGTGPSYIAMVEDENVEKVKEKLNRYGKVILTKPNNDGASIY

Specific function: Unknown

COG id: COG1685

COG function: function code EH; Archaeal shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROK_METJA (Q58835)

Other databases:

- EMBL:   L77117
- PIR:   G64479
- RefSeq:   NP_248444.1
- ProteinModelPortal:   Q58835
- SMR:   Q58835
- GeneID:   1452344
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1440
- NMPDR:   fig|243232.1.peg.1481
- TIGR:   MJ1440
- HOGENOM:   HBG646614
- OMA:   AFDDACA
- ProtClustDB:   PRK01123
- BioCyc:   MJAN243232:MJ_1440-MONOMER
- BRENDA:   2.7.1.71
- GO:   GO:0005737
- HAMAP:   MF_00370
- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR010189
- Gene3D:   G3DSA:3.30.230.10
- PIRSF:   PIRSF005758
- TIGRFAMs:   TIGR01920

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =2.7.1.71

Molecular weight: Translated: 30598; Mature: 30598

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00627 GHMP_KINASES_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGKAYALASGTIINAIATGKGSAFGLDLKVYAKVKLIDDGKNKIEGKVLDNPNIKPNLI
CCCCEEEEECCCEEEEEECCCCCEEEEEEEEEEEEEEEECCCCCCCEEEECCCCCCHHHH
VRCVKNTLDYFGLNYSAYVETKTEIPIKSGLSSSSATSNAVVLATFDALGEKIDDELILN
HHHHHHHHHHHCCCEEEEEEECCCCCHHCCCCCCCCCCCEEEEEEHHHHCCCCCCEEEEE
LGIKSSFDEKLTVTGAYDDATASYYGGITITDNIERKILKRDKMRDDLNVLILIPNLEKN
ECCCCCCCCEEEEEECCCCCCHHHCCCEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCC
VDVNRMKLIKDYVEIAFNEAINGNYFKALFLNGILYASALNFPTNIAIDALDAGAITAGL
CCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHEEHHCCCCCCEEEEEECCCCEEECC
SGTGPSYIAMVEDENVEKVKEKLNRYGKVILTKPNNDGASIY
CCCCCCEEEEEECCCHHHHHHHHHHCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MEGKAYALASGTIINAIATGKGSAFGLDLKVYAKVKLIDDGKNKIEGKVLDNPNIKPNLI
CCCCEEEEECCCEEEEEECCCCCEEEEEEEEEEEEEEEECCCCCCCEEEECCCCCCHHHH
VRCVKNTLDYFGLNYSAYVETKTEIPIKSGLSSSSATSNAVVLATFDALGEKIDDELILN
HHHHHHHHHHHCCCEEEEEEECCCCCHHCCCCCCCCCCCEEEEEEHHHHCCCCCCEEEEE
LGIKSSFDEKLTVTGAYDDATASYYGGITITDNIERKILKRDKMRDDLNVLILIPNLEKN
ECCCCCCCCEEEEEECCCCCCHHHCCCEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCC
VDVNRMKLIKDYVEIAFNEAINGNYFKALFLNGILYASALNFPTNIAIDALDAGAITAGL
CCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHEEHHCCCCCCEEEEEECCCCEEECC
SGTGPSYIAMVEDENVEKVKEKLNRYGKVILTKPNNDGASIY
CCCCCCEEEEEECCCHHHHHHHHHHCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11114929