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The map label for this gene is fucA

Identifier: 15669609

GI number: 15669609

Start: 1381145

End: 1381690

Strand: Direct

Name: fucA

Synonym: MJ1418

Alternate gene names: 15669609

Gene position: 1381145-1381690 (Clockwise)

Preceding gene: 15669608

Following gene: 15669611

Centisome position: 82.95

GC content: 28.94

Gene sequence:

>546_bases
ATGGACAAAAAGCAATTTATTAAAATATGTAGAAAATTGTATGATAGGAAATATGTTGTAGGTAGTGGAGGCAATGTATC
AGTTAAAGAGGGGGATAAAATATATCTGACTCCAACTGGCTCTATTTTAGGGTTTTTAAAGGAAGATGATATAGCTGAAA
TGGATTTGGATGGTAATGTTATAAAAGGAAAACCTACATCAGAAAAAAATCTCCACTTAATGATTTATAGAAAAAGAAAT
GACATAAACGCAATAATCCACACTCATTCACTTATATCAACTTTTTTATCGACAATAAACAAAGAAATAGAACTTTTAAC
ACCAGAAGGAAAAATATTTTTGAAGAAAATTGGTTATGTTGATTACTATGAGGCAGGTAGTTTAAAATTAGCTGAAGAAA
CAGCAAAAAGAGATGAGGACGTTATTATATTAAAAAATCATGGAGTAGTTTGTTTAGGTAAAGATTTGATAGATGCATAT
ATAAAAGTGGAGGTTTTAGAAGAACAAGCTAAACTTACACTTTTAAACCTTCTTGTAAAGAAATAG

Upstream 100 bases:

>100_bases
TCCGCATTAATATCATAATCTTAGGGATTTTAATTGTATTTCTTTATATAACGGTTATAATCTTGATGTTGAAACTAATA
AAAATATTTTAAGTGAGATT

Downstream 100 bases:

>100_bases
TGGGGATTTTTAAATTTATTTAACTCTTTCTAATTCACTAACAATACTCCAAATTTGTGTTCTTGTGTGAAGTGGCATGT
TTGGGTCGTTGCTAATCTCA

Product: fuculose-1-phosphate aldolase FucA

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MDKKQFIKICRKLYDRKYVVGSGGNVSVKEGDKIYLTPTGSILGFLKEDDIAEMDLDGNVIKGKPTSEKNLHLMIYRKRN
DINAIIHTHSLISTFLSTINKEIELLTPEGKIFLKKIGYVDYYEAGSLKLAEETAKRDEDVIILKNHGVVCLGKDLIDAY
IKVEVLEEQAKLTLLNLLVKK

Sequences:

>Translated_181_residues
MDKKQFIKICRKLYDRKYVVGSGGNVSVKEGDKIYLTPTGSILGFLKEDDIAEMDLDGNVIKGKPTSEKNLHLMIYRKRN
DINAIIHTHSLISTFLSTINKEIELLTPEGKIFLKKIGYVDYYEAGSLKLAEETAKRDEDVIILKNHGVVCLGKDLIDAY
IKVEVLEEQAKLTLLNLLVKK
>Mature_181_residues
MDKKQFIKICRKLYDRKYVVGSGGNVSVKEGDKIYLTPTGSILGFLKEDDIAEMDLDGNVIKGKPTSEKNLHLMIYRKRN
DINAIIHTHSLISTFLSTINKEIELLTPEGKIFLKKIGYVDYYEAGSLKLAEETAKRDEDVIILKNHGVVCLGKDLIDAY
IKVEVLEEQAKLTLLNLLVKK

Specific function: Catalyzes the reversible aldol cleavage of L-fuculose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. The substrate preference order is glyceraldehyde > DL- lactaldehyde, glycolaldehyde > acrolein > formaldehyde, methylglyoxal > acet

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily

Homologues:

Organism=Escherichia coli, GI1789094, Length=182, Percent_Identity=32.967032967033, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1789164, Length=183, Percent_Identity=28.9617486338798, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FUCA_METJA (Q58813)

Other databases:

- EMBL:   L77117
- PIR:   A64477
- RefSeq:   NP_248422.1
- ProteinModelPortal:   Q58813
- GeneID:   1452322
- GenomeReviews:   L77117_GR
- KEGG:   mja:MJ_1418
- NMPDR:   fig|243232.1.peg.1459
- TIGR:   MJ1418
- HOGENOM:   HBG541069
- OMA:   IVHLHST
- ProtClustDB:   CLSK876567
- BioCyc:   MetaCyc:MONOMER-12176
- BioCyc:   MJAN243232:MJ_1418-MONOMER
- InterPro:   IPR001303
- Gene3D:   G3DSA:3.40.225.10

Pfam domain/function: PF00596 Aldolase_II; SSF53639 Aldolase_II_N

EC number: =4.1.2.17

Molecular weight: Translated: 20470; Mature: 20470

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKQFIKICRKLYDRKYVVGSGGNVSVKEGDKIYLTPTGSILGFLKEDDIAEMDLDGNV
CCHHHHHHHHHHHHCCEEEEECCCEEEEECCCEEEEEECHHHEEEECCCCCEEECCCCCE
IKGKPTSEKNLHLMIYRKRNDINAIIHTHSLISTFLSTINKEIELLTPEGKIFLKKIGYV
EECCCCCCCCEEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCE
DYYEAGSLKLAEETAKRDEDVIILKNHGVVCLGKDLIDAYIKVEVLEEQAKLTLLNLLVK
EEECCCCEEEHHHHHCCCCCEEEECCCCEEEECHHHHHHHHHHEEHHHHHHHHHHHHHHC
K
C
>Mature Secondary Structure
MDKKQFIKICRKLYDRKYVVGSGGNVSVKEGDKIYLTPTGSILGFLKEDDIAEMDLDGNV
CCHHHHHHHHHHHHCCEEEEECCCEEEEECCCEEEEEECHHHEEEECCCCCEEECCCCCE
IKGKPTSEKNLHLMIYRKRNDINAIIHTHSLISTFLSTINKEIELLTPEGKIFLKKIGYV
EECCCCCCCCEEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCE
DYYEAGSLKLAEETAKRDEDVIILKNHGVVCLGKDLIDAYIKVEVLEEQAKLTLLNLLVK
EEECCCCEEEHHHHHCCCCCEEEECCCCEEEECHHHHHHHHHHEEHHHHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087